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Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 7, 2015; 21(21): 6499-6517
Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6499
Role of dietary polyphenols in the management of peptic ulcer
Mohammad Hosein Farzaei, Mohammad Abdollahi, Roja Rahimi
Mohammad Hosein Farzaei, Mohammad Abdollahi, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran 1417614411, Iran
Mohammad Hosein Farzaei, Roja Rahimi, Department of Traditional Pharmacy, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran 1114733114, Iran
Mohammad Hosein Farzaei, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah 6734667149, Iran
Author contributions: Farzaei MH contributed to study design, data collection, and drafting the manuscript; Abdollahi M contributed to study design, editing the manuscript, and English language editing; Rahimi R reviewed data collection and supervised the entire study.
Supported by National Elites Foundation of Iran (partly).
Conflict-of-interest: The authors have no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Roja Rahimi, PhD, Department of Traditional Pharmacy, School of Traditional Medicine, Tehran University of Medical Sciences, Amir Abad, Keshavarz Boulevard, Tehran 1114733114, Iran. rojarahimi@gmail.com
Telephone: +98-215-5693523 Fax: +98-215-5693523
Received: November 26, 2014
Peer-review started: November 26, 2014
First decision: February 10, 2015
Revised: February 22, 2015
Accepted: April 3, 2015
Article in press: April 3, 2015
Published online: June 7, 2015
Core Tip

Core tip: Polyphenols ubiquitously present in vegetables and fruits are progressively viewed as natural dietary ingredients vital for a balanced diet. An accumulating body of evidence indicates that dietary polyphenols with multiple biological mechanisms of action play a pivotal part in the management of gastric and duodenal ulcers. Administration of a sufficient amount of dietary polyphenols in the human diet or as part of dietary supplementation along with conventional treatment can result in perfect prevention and treatment of peptic ulcer.