Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 7, 2015; 21(13): 3801-3812
Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3801
Gastrointestinal Behçet's disease: A review
Wasseem Skef, Matthew J Hamilton, Thurayya Arayssi
Wasseem Skef, Department of Medicine, St. Elizabeth’s Medical Center, Boston, MA 02135, United States
Matthew J Hamilton, Division of Gastroenterology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, United States
Thurayya Arayssi, Weill Cornell Medical College in Qatar, Doha 24144, Qatar
Author contributions: Skef W performed the literature review and wrote the paper; Hamilton MJ and Arayssi T provided expertise and critical revision of the manuscript.
Conflict-of-interest: The authors report no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Dr. Thurayya Arayssi, Weill Cornell Medical College in Qatar, Doha 24144, Qatar.
Telephone: +974-44-928329 Fax: +974-44-928377
Received: November 15, 2014
Peer-review started: November 17, 2014
First decision: December 26, 2014
Revised: January 14, 2015
Accepted: January 30, 2015
Article in press: January 30, 2015
Published online: April 7, 2015
Core Tip

Core tip: Behçet’s disease is an uncommon subtype of inflammatory bowel disease. It can present with a wide array of clinical manifestations that may mimic other diseases including Crohn’s disease. Establishing the diagnosis remains a challenge and clinicians must be aware of the relevant clinical manifestations and diagnostic considerations. The optimal medical management is limited by the lack of rigorous clinical trial data.