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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 7, 2015; 21(13): 4014-4019
Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4014
Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4014
Endoscopic ultrasound elastography strain histograms in the evaluation of patients with pancreatic masses
Dalibor Opačić, Zvonimir Ostojić, Clinical Hospital Center Zagreb, 10000 Zagreb, Croatia
Nadan Rustemović, Mirjana Kalauz, Pave Markoš, Matea Majerović, Milorad Opačić, Division of Gastroenterology, Clinical Hospital Center Zagreb, 10000 Zagreb, Croatia
Iva Ledinsky, Clinic for Tumors, Clinical Hospital Center “Sisters of Mercy”, 10000 Zagreb, Croatia
Ana Višnjić, Juraj Krznarić, Medical Faculty University of Zagreb, 10000 Zagreb, Croatia
Milorad Opačić, Department of Internal Medicine, Division of Gastroenterology, University Hospital Center Zagreb, 10000 Zagreb, Croatia
Author contributions: Opačić D, Rustemović N and Kalauz M designed the research and supervised realization of the manuscript; Markoš P, Ostojić Z and Majerović M wrote the paper; Ledinsky I, Višnjić A and Krznarić J collected and analyzed data and contributed to technical support; Opačić M critically revised the manuscript for important intellectual content; all the authors gave their approval to the final version to be published.
Supported by Croatian Ministry of Science, project number 0214214.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Milorad Opačić, MD, Assistant Professor, Department of Internal Medicine, Division of Gastroenterology, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia. opacic.m@gmail.com
Telephone: +385-1-2388041 Fax: +385-1-2376027
Received: August 7, 2014
Peer-review started: August 8, 2014
First decision: August 27, 2014
Revised: October 2, 2014
Accepted: November 18, 2014
Article in press: November 19, 2014
Published online: April 7, 2015
Peer-review started: August 8, 2014
First decision: August 27, 2014
Revised: October 2, 2014
Accepted: November 18, 2014
Article in press: November 19, 2014
Published online: April 7, 2015
Core Tip
Core tip: Endoscopic ultrasound quantitative elastography strain histograms (SHs) are a recently developed method for non-invasive differentiation of pancreatic masses. In a prospective single center study, 105 patients with pancreatic masses and 44 controls were evaluated. For SH measurements, Hitachi software was used and applied for the first time in a clinical study as far as we know. We determined the accuracy of the method and a cut-off value between malignant pancreatic tumors and mass-forming pancreatitis. A new variable, the SH ratio, is calculated in an attempt to improve the sensitivity, specificity and accuracy of the method.