Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 7, 2015; 21(13): 3936-3943
Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3936
Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3936
Eradication rate and histological changes after Helicobacter pylori eradication treatment in gastric cancer patients following subtotal gastrectomy
Jae Jin Hwang, Dong Ho Lee, Kyu Keun Kang, Ae-Ra Lee, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do 463-707, South Korea
Author contributions: Hwang JJ, Lee DH and Kang KK were responsible for the study conception and design, data analysis and interpretation, and manuscript drafting; Lee AR, Yoon H, Shin CM, Park YS and Kim N critically revised the article for important intellectual content; all the authors reviewed and approved the final version to be published.
Ethics approval: The study was reviewed and approved by the Seoul National University Bundang Hospital Institutional Review Board.
Informed consent: All patients gave informed written consent prior to being enrolled in the study.
Conflict-of-interest: No potential conflicts of interest relevant to this article were reported.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dong Ho Lee, MD, Department of Internal Medicine, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam, Gyeonggi-do 463-707, South Korea. dhljohn@yahoo.co.kr
Telephone: +82-31-7877006 Fax: +82-31-7874051
Received: November 3, 2014
Peer-review started: November 4, 2014
First decision: November 26, 2014
Revised: December 7, 2014
Accepted: January 8, 2015
Article in press: January 8, 2015
Published online: April 7, 2015
Peer-review started: November 4, 2014
First decision: November 26, 2014
Revised: December 7, 2014
Accepted: January 8, 2015
Article in press: January 8, 2015
Published online: April 7, 2015
Core Tip
Core tip: This is the first study to investigate the eradication rate and histological changes after Helicobacter pylori (H. pylori) eradication treatment in patients following subtotal gastrectomy for gastric cancer. The patients with H. pylori infection who had undergone a subtotal gastrectomy for gastric cancer had a similar eradication rate to patients with an intact stomach. H. pylori eradication in gastric cancer patients following subtotal gastrectomy resulted in histological improvement, especially in the Billroth II group.