Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3773
Peer-review started: September 3, 2014
First decision: October 29, 2014
Revised: November 18, 2014
Accepted: December 14, 2014
Article in press: December 16, 2014
Published online: April 7, 2015
Core tip: The association between Helicobacter pylori (H. pylori) and gastric mucosa-associated lymphoid tissue lymphoma has a long history and H. pylori eradication is the standard of care in these cases. In recent years, it has been shown that high-grade, early-stage gastric lymphoma may be dependent on H. pylori and eradication of this microorganism may be curative in some of the cases with gastric diffuse large B cell lymphoma. However, chemotherapy is a standard approach in cases unresponsive to H. pylori eradication.