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Topic Highlight
Medical management of gastric cancer: A 2014 update 
Elena Elimova, Hironori Shiozaki, Roopma Wadhwa, Kazuki Sudo, Qiongrong Chen, Jeannelyn S Estrella, Mariela A Blum, Brian Badgwell, Prajnan Das, Shumei Song, Jaffer A Ajani 
World J Gastroenterol 20(38):13637-13647. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13637
Proteomic and metabolic prediction of response to therapy in gastric cancer 
Michaela Aichler, Birgit Luber, Florian Lordick, Axel Walch 
World J Gastroenterol 20(38):13648-13657. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13648
MicroRNAs: Promising chemoresistance biomarkers in gastric cancer with diagnostic and therapeutic potential 
Christiane Matuszcak, Joerg Haier, Richard Hummel, Kirsten Lindner 
World J Gastroenterol 20(38):13658-13666. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13658
Subtotal gastrectomy for gastric cancer 
Roberto Santoro, Giuseppe Maria Ettorre, Eugenio Santoro 
World J Gastroenterol 20(38):13667-13680. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13667
Screening for and surveillance of gastric cancer 
Debora Compare, Alba Rocco, Gerardo Nardone 
World J Gastroenterol 20(38):13681-13691. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13681
Improving the outcomes in gastric cancer surgery 
Juul JW Tegels, Michiel FG De Maat, Karel WE Hulsewé, Anton GM Hoofwijk, Jan HMB Stoot 
World J Gastroenterol 20(38):13692-13704. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13692
Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells 
Oleksandr H Minchenko, Katsuya Tsuchihara, Dmytro O Minchenko, Andreas Bikfalvi, Hiroyasu Esumi 
World J Gastroenterol 20(38):13705-13717. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13705
Adjuvant therapy for gastric cancer: Current and future directions 
Marcus Foo, Trevor Leong 
World J Gastroenterol 20(38):13718-13727. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13718
Clinical significance of molecular diagnosis for gastric cancer lymph node micrometastasis 
Hiromichi Sonoda, Tohru Tani 
World J Gastroenterol 20(38):13728-13733. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13728
Gastric cancer arising from the remnant stomach after distal gastrectomy: A review 
Shinsuke Takeno, Tatsuya Hashimoto, Kenji Maki, Ryosuke Shibata, Hironari Shiwaku, Ippei Yamana, Risako Yamashita, Yuichi Yamashita 
World J Gastroenterol 20(38):13734-13740. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13734
Molecular targeting to treat gastric cancer 
Keishiro Aoyagi, Kikuo Kouhuji, Junya Kizaki, Taro Isobe, Kousuke Hashimoto, Kazuo Shirouzu 
World J Gastroenterol 20(38):13741-13755. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13741
Rho/ROCK signaling in motility and metastasis of gastric cancer 
Tasuku Matsuoka, Masakazu Yashiro 
World J Gastroenterol 20(38):13756-13766. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13756
Current issues and future perspectives of gastric cancer screening 
Chisato Hamashima 
World J Gastroenterol 20(38):13767-13774. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13767
Is endoscopic ultrasonography still the modality of choice in preoperative staging of gastric cancer? 
Sung Wook Hwang, Dong Ho Lee 
World J Gastroenterol 20(38):13775-13782. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13775
New approaches to gastric cancer staging: Beyond endoscopic ultrasound, computed tomography and positron emission tomography 
Hyuk Yoon, Dong Ho Lee 
World J Gastroenterol 20(38):13783-13790. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13783
Potential prognostic, diagnostic and therapeutic markers for human gastric cancer 
Ming-Ming Tsai, Chia-Siu Wang, Chung-Ying Tsai, Hsiang-Cheng Chi, Yi-Hsin Tseng, Kwang-Huei Lin 
World J Gastroenterol 20(38):13791-13803. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13791
Virtual gastrointestinal colonoscopy in combination with large bowel endoscopy: Clinical application 
Qing He, Ting Rao, Yong-Song Guan 
World J Gastroenterol 20(38):13820-13832. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13820
Pathology of pancreatic ductal adenocarcinoma: Facts, challenges and future developments 
Irene Esposito, Björn Konukiewitz, Anna Melissa Schlitter, Günter Klöppel 
World J Gastroenterol 20(38):13833-13841. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13833
Gastric cancer: Prevention, screening and early diagnosis 
Victor Pasechnikov, Sergej Chukov, Evgeny Fedorov, Ilze Kikuste, Marcis Leja 
World J Gastroenterol 20(38):13842-13862. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13842
Inflammatory bowel disease and thromboembolism 
Petros Zezos, Georgios Kouklakis, Fred Saibil 
World J Gastroenterol 20(38):13863-13878. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13863
Update on surgical treatment of pancreatic neuroendocrine neoplasms 
Jan G D’Haese, Chiara Tosolini, Güralp O Ceyhan, Bo Kong, Irene Esposito, Christoph W Michalski, Jörg Kleeff 
World J Gastroenterol 20(38):13893-13898. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13893
Epithelial cysts of the spleen: A minireview 
Sachin B Ingle, Chitra R Hinge (Ingle), Swapna Patrike 
World J Gastroenterol 20(38):13899-13903. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13899
Gastric leaks post sleeve gastrectomy: Review of its prevention and management 
Antoine Abou Rached, Melkart Basile, Hicham El Masri 
World J Gastroenterol 20(38):13904-13910. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13904
Original Article
Distribution of the P2X2 receptor and chemical coding in ileal enteric neurons of obese male mice (ob/ob
Márcia Sanae Mizuno, Amanda Rabello Crisma, Primavera Borelli, Bárbara Tavares Schäfer, Mariana Póvoa Silveira, Patricia Castelucci 
World J Gastroenterol 20(38):13911-13919. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13911
Real time shear wave elastography in chronic liver diseases: Accuracy for predicting liver fibrosis, in comparison with serum markers 
Jae Yoon Jeong, Tae Yeob Kim, Joo Hyun Sohn, Yongsoo Kim, Woo Kyoung Jeong, Young-Ha Oh, Kyo-Sang Yoo 
World J Gastroenterol 20(38):13920-13929. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13920
Retrospective Cohort Study
Acute bacterial infection negatively impacts cancer specific survival of colorectal cancer patients 
Regina Attiê, Ludmilla Thomé Domingos Chinen, Eliane Muta Yoshioka, Michele Cristina F Silva, Vladmir Cláudio Cordeiro de Lima 
World J Gastroenterol 20(38):13930-13935. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13930
Retrospective Study
Endoscopic stenting for recurrence-related colorectal anastomotic site obstruction: Preliminary experience 
Jung Ho Kim, Jong Joon Lee, Jae Hee Cho, Kyoung Oh Kim, Jun-Won Chung, Yoon Jae Kim, Kwang An Kwon, Dong Kyun Park, Ju Hyun Kim 
World J Gastroenterol 20(38):13936-13941. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13936
Stratified computed tomography findings improve diagnostic accuracy for appendicitis 
Geon Park, Sang Chul Lee, Byung-Jo Choi, Say-June Kim 
World J Gastroenterol 20(38):13942-13949. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13942
Enhanced recovery after surgery vs conventional care in emergency colorectal surgery 
Varut Lohsiriwat 
World J Gastroenterol 20(38):13950-13955. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13950
Characteristics and clinical outcome of nonsteroidal anti-inflammatory drug-induced acute hepato-nephrotoxicity among Chinese patients 
Ya-Li Cao, Zhi-Gang Tian, Fang Wang, Wen-Ge Li, Dan-Ying Cheng, Yan-Fang Yang, Hong-Mei Gao 
World J Gastroenterol 20(38):13956-13965. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13956
Laparoscopic spleen-preserving distal pancreatectomy for pancreatic neoplasms: A retrospective study 
Jia-Fei Yan, Xiao-Wu Xu, Wei-Wei Jin, Chao-Jie Huang, Ke Chen, Ren-Chao Zhang, Ajoodhea Harsha, Yi-Ping Mou 
World J Gastroenterol 20(38):13966-13972. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13966
Simultaneous modulated accelerated radiation therapy for esophageal cancer: A feasibility study 
Wu-Zhe Zhang, Jian-Zhou Chen, De-Rui Li, Zhi-Jian Chen, Hong Guo, Ting-Ting Zhuang, Dong-Sheng Li, Ming-Zhen Zhou, Chuang-Zhen Chen 
World J Gastroenterol 20(38):13973-13980. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13973
Endoscopic full-thickness resection for gastric submucosal tumors arising from the muscularis propria layer 
Liu-Ye Huang, Jun Cui, Shu-Juan Lin, Bo Zhang, Cheng-Rong Wu 
World J Gastroenterol 20(38):13981-13986. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13981
Clinical Trials Study
S-1 plus gemcitabine chemotherapy followed by concurrent radiotherapy and maintenance therapy with S-1 for unresectable pancreatic cancer 
Qing-Hua Ke, Shi-Qiong Zhou, Ji-Yuan Yang, Wei Du, Gai Liang, Yong Lei, Fei Luo 
World J Gastroenterol 20(38):13987-13992. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13987
Observational Study
Epistaxis in end stage liver disease masquerading as severe upper gastrointestinal hemorrhage 
Marine Camus, Dennis M Jensen, Jason D Matthews, Gordon V Ohning, Thomas O Kovacs, Rome Jutabha, Kevin A Ghassemi, Gustavo A Machicado, Gareth S Dulai 
World J Gastroenterol 20(38):13993-13998. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13993
Small intestinal bacterial overgrowth in inactive Crohn’s disease: Influence of thiopurine and biological treatment 
Cristina Sánchez-Montes, Vicente Ortiz, Guillermo Bastida, Ester Rodríguez, María Yago, Belén Beltrán, Mariam Aguas, Marisa Iborra, Vicente Garrigues, Julio Ponce, Pilar Nos 
World J Gastroenterol 20(38):13999-14003. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13999
Magnetic resonance enterography in refractory iron deficiency anemia: A pictorial overview 
Ismet Cengic, Derya Tureli, Hilal Aydin, Onur Bugdayci, Nese Imeryuz, Davut Tuney 
World J Gastroenterol 20(38):14004-14009. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14004
Prospective Study
Apolipoprotein C3 (-455T>C) polymorphism confers susceptibility to nonalcoholic fatty liver disease in the Southern Han Chinese population 
Min-Rui Li, Sheng-Hong Zhang, Kang Chao, Xian-Hua Liao, Jia-Yan Yao, Min-Hu Chen, Bi-Hui Zhong 
World J Gastroenterol 20(38):14010-14017. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14010
Systematic Reviews
Cytoreductive surgery and intraperitoneal chemotherapy for colorectal peritoneal metastases 
Reza Mirnezami, Brendan J Moran, Kate Harvey, Tom Cecil, Kandiah Chandrakumaran, Norman Carr, Faheez Mohamed, Alexander H Mirnezami 
World J Gastroenterol 20(38):14018-14032. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14018
Biliary stenting with or without sphincterotomy for malignant biliary obstruction: A meta-analysis 
Pei-Jing Cui, Jing Yao, Yi-Jun Zhao, Hua-Zhong Han, Jun Yang 
World J Gastroenterol 20(38):14033-14039. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14033
Accuracy of early detection of colorectal tumours by stool methylation markers: A meta-analysis 
Hu Zhang, Jian Qi, Ya-Qiong Wu, Ping Zhang, Jun Jiang, Qi-Xian Wang, You-Qing Zhu 
World J Gastroenterol 20(38):14040-14050. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14040
Bone marrow-derived mesenchymal stem cell therapy for decompensated liver cirrhosis: A meta-analysis 
Xing-Nan Pan, Lian-Qiu Zheng, Xiao-Huan Lai 
World J Gastroenterol 20(38):14051-14057. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14051
Case Report
Intestinal ascariasis at pediatric emergency room in a developed country 
Shuichiro Umetsu, Tsuyoshi Sogo, Kentaro Iwasawa, Takeo Kondo, Tomoyuki Tsunoda, Manari Oikawa-Kawamoto, Haruki Komatsu, Ayano Inui, Tomoo Fujisawa 
World J Gastroenterol 20(38):14058-14062. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14058
Intramedullary spinal cord metastasis from pancreatic neuroendocrine tumor 
Jung Ho Kim, Chang Lim Hyun, Sang Hoon Han 
World J Gastroenterol 20(38):14063-14067. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14063
Complete body-neck torsion of the gallbladder: A case report 
Ta-Wei Pu, Chun-Yu Fu, Huai-En Lu, Wei-Tung Cheng 
World J Gastroenterol 20(38):14068-14072. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14068
Successful treatment of refractory gastric antral vascular ectasia by distal gastrectomy: A case report 
Ting Jin, Bao-Ying Fei, Wei-Hua Zheng, Yong-Xiang Wang 
World J Gastroenterol 20(38):14073-14075. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14073
Small intestinal vascular malformation bleeding: A case report with imaging findings 
Jun Cui, Liu-Ye Huang, Shu-Juan Lin, Long-Zhi Yi, Cheng-Rong Wu, Bo Zhang 
World J Gastroenterol 20(38):14076-14078. Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14076