Rho/ROCK signaling in motility and metastasis of gastric cancer

doi:10.3748/wjg.v20.i38.13756

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 20, Issue 38

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (13349)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-3) series, Tables (1-1) series.

Item

Count

PDF

1037

WORD

366

HTML

9370

Figures (1-3)

356

Tables (1-1)

119

Sum=11248

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1124

Download

977

Sum=2101

Oct 14, 2014 (publication date) through Apr 22, 2024

Times Cited of This Article

Times Cited (70)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Gastroenterol. Oct 14, 2014; 20(38): 13756-13766
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13756

Rho/ROCK signaling in motility and metastasis of gastric cancer

Tasuku Matsuoka, Masakazu Yashiro

Tasuku Matsuoka, Masakazu Yashiro, Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan

Author contributions: Matsuoka T and Yashiro M designed this review; Matsuoka T wrote manuscript and Yashiro M edited manuscript.

Supported by KAKENHI Grant-in-Aid for Scientific Research, No. 23390329; and the National Cancer Center Research and Development Fund, No. 23-A-9

Correspondence to: Masakazu Yashiro, MD, Department of Surgical Oncology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. m9312510@med.osaka-cu.ac.jp

Telephone: +81-6-66453838 Fax: +81-6-66466450

Received: October 28, 2013
Revised: April 21, 2014
Accepted: June 12, 2014
Published online: October 14, 2014

Core Tip

Core tip: Gastric cancer is one of the main causes of cancer-associated death in the worldwide. The poor prognosis associated with gastric cancer is mainly related to metastasis and cell motility is vital for several steps involved in the metastasis. Rho GTPases could affect cancer progression including cytoskeletal dynamics. This study aimed at gaining further insight into the mechanism of Rho/Rho-associated protein kinases pathway mediated gastric cancer metastasis, particularly with regard to cell movement.