Proteomic and metabolic prediction of response to therapy in gastric cancer

Table 1 Potential biomarkers for therapy response prediction in gastric cancer

Ref.	Biomarker	Sample	Patients	Chemotherapy
Huang et al[25], 2013	AMBP	Serum	17 GC patients	paclitaxel, capecitabine
Sekikawa et al[26], 2013	REG Iα	Tissue	70 GC patients	S-1, Cisplatin
Okada et al[27], 2013	FOXM1	Tissue	81 GC patients	docetaxel, 5-FU, cisplatin/5-FU, cisplatin
Sugita et al[28], 2010	BNIP3	Tissue	80 GC patients	5-FU, irinotecan/docetaxel/cisplatin
	DAPK
Mitani et al[29], 2007	REG4	Serum	36 GC patients	5-FU, cisplatin

AMBP: Alpha-1 microglobulin/bikunin precursor; REG Iα: Regenerating gene Iα; FoxM1: Forkhead box M1 transcription factor; BNIP3: Bcl-2/adenovirus E1B 19 kDa-interacting protein 3; DAPK: Death associated protein kinase; REG IV: Regenerating gene IV; GC: Gastric cancer; 5-FU: 5-fluorouracil.