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Open-Access Journal
Editorial
Esophagitis and its causes: Who is “guilty” when acid is found “not guilty”? 
Laurino Grossi, Antonio Francesco Ciccaglione, Leonardo Marzio 
World J Gastroenterol 23(17):3011-3016. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3011
Checkpoint inhibitors in gastrointestinal cancers: Expectations and reality 
Hampig Raphael Kourie, Samer Tabchi, Marwan Ghosn 
World J Gastroenterol 23(17):3017-3021. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3017
Frontier
BRAF inhibitor treatment of melanoma causing colonic polyps: An alternative hypothesis 
Fergal C Kelleher, Grainne Callaghan, Catriona Gallagher, Hazel O’Sullivan 
World J Gastroenterol 23(17):3022-3029. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3022
Review
Genes, emotions and gut microbiota: The next frontier for the gastroenterologist 
Arturo Panduro, Ingrid Rivera-Iñiguez, Maricruz Sepulveda-Villegas, Sonia Roman 
World J Gastroenterol 23(17):3030-3042. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3030
Macrophage inflammatory protein-2 as mediator of inflammation in acute liver injury 
Chao-Chao Qin, Yan-Ning Liu, Ying Hu, Ying Yang, Zhi Chen 
World J Gastroenterol 23(17):3043-3052. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3043
Basic Study
CXCR7/CXCL12 axis is involved in lymph node and liver metastasis of gastric carcinoma 
Qi Xin, Na Zhang, Hai-Bo Yu, Qin Zhang, Yan-Fen Cui, Chuan-Shan Zhang, Zhe Ma, Yan Yang, Wei Liu 
World J Gastroenterol 23(17):3053-3065. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3053
Low-grade slightly elevated and polypoid colorectal adenomas display differential β-catenin-TCF/LEF activity, c-Myc, and cyclin D1 expression 
Tian-Wen Yang, Yun-Han Gao, Sha-Ying Ma, Qiang Wu, Zhong-Fu Li 
World J Gastroenterol 23(17):3066-3076. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3066
Retrospective Cohort Study
Pancreaticoduodenectomy in patients ≥ 75 years of age: Are there any differences with other age ranges in oncological and surgical outcomes? Results from a tertiary referral center 
Salvatore Paiella, Matteo De Pastena, Tommaso Pollini, Giovanni Zancan, Debora Ciprani, Giulia De Marchi, Luca Landoni, Alessandro Esposito, Luca Casetti, Giuseppe Malleo, Giovanni Marchegiani, Massimiliano Tuveri, Enrico Marrano, Laura Maggino, Erica Secchettin, Deborah Bonamini, Claudio Bassi, Roberto Salvia 
World J Gastroenterol 23(17):3077-3083. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3077
Retrospective Study
New flexible endoscopic controlled stapler technique for the treatment of Zenker's diverticulum: A case series 
Johanna Wilmsen, Robert Baumbach, Dietmar Stüker, Vincens Weingart, Frank Neser, Stefan Karl Gölder, Christof Pfundstein, Ellen Claudia Nötzel, Thomas Rösch, Siegbert Faiss 
World J Gastroenterol 23(17):3084-3091. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3084
Comparison of imaging-based and pathological dimensions in pancreatic neuroendocrine tumors 
Salvatore Paiella, Harmony Impellizzeri, Elisabetta Zanolin, Giovanni Marchegiani, Marco Miotto, Anna Malpaga, Riccardo De Robertis, Mirko D'Onofrio, Borislav Rusev, Paola Capelli, Sara Cingarlini, Giovanni Butturini, Maria Vittoria Davì, Antonio Amodio, Claudio Bassi, Aldo Scarpa, Roberto Salvia, Luca Landoni 
World J Gastroenterol 23(17):3092-3098. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3092
Octogenarian liver grafts: Is their use for transplant currently justified? 
Carlos Jiménez-Romero, Felix Cambra, Oscar Caso, Alejandro Manrique, Jorge Calvo, Alejandro Marcacuzco, Paula Rioja, David Lora, Iago Justo 
World J Gastroenterol 23(17):3099-3110. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3099
Rate of local tumor progression following radiofrequency ablation of pathologically early hepatocellular carcinoma 
Yoshiteru Hao, Kazushi Numata, Tomohiro Ishii, Hiroyuki Fukuda, Shin Maeda, Masayuki Nakano, Katsuaki Tanaka 
World J Gastroenterol 23(17):3111-3121. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3111
Prognostic value of the neutrophil-to-lymphocyte ratio for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis 
Shao-Hua Li, Qiao-Xuan Wang, Zhong-Yuan Yang, Wu Jiang, Cong Li, Peng Sun, Wei Wei, Ming Shi, Rong-Ping Guo 
World J Gastroenterol 23(17):3122-3132. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3122
Clinical Trials Study
Diagnostic value of gadobenate dimeglumine-enhanced hepatocyte-phase magnetic resonance imaging in evaluating hepatic fibrosis and hepatitis 
Xiu-Mei Li, Zhu Chen, En-Hua Xiao, Quan-Liang Shang, Cong Ma 
World J Gastroenterol 23(17):3133-3141. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3133
Observational Study
Consequences of metabolic syndrome on postoperative outcomes after pancreaticoduodenectomy 
Alban Zarzavadjian Le Bian, David Fuks, Sophie Chopinet, Sébastien Gaujoux, Manuela Cesaretti, Renato Costi, Ajay P Belgaumkar, Claude Smadja, Brice Gayet 
World J Gastroenterol 23(17):3142-3149. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3142
Effect of a counseling-supported treatment with the Mediterranean diet and physical activity on the severity of the non-alcoholic fatty liver disease 
Chiara Gelli, Mirko Tarocchi, Ludovico Abenavoli, Laura Di Renzo, Andrea Galli, Antonino De Lorenzo 
World J Gastroenterol 23(17):3150-3162. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3150
Prospective Study
Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients 
Marcelo Soto, Laura Sampietro-Colom, Luis Lasalvia, Aurea Mira, Wladimiro Jiménez, Miquel Navasa 
World J Gastroenterol 23(17):3163-3173. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3163
Impact of gastroesophageal reflux control through tailored proton pump inhibition therapy or fundoplication in patients with Barrett’s esophagus 
Francisco Baldaque-Silva, Michael Vieth, Mumen Debel, Bengt Håkanson, Anders Thorell, Nuno Lunet, Huan Song, Miguel Mascarenhas-Saraiva, Gisela Pereira, Lars Lundell, Hanns-Ulrich Marschall 
World J Gastroenterol 23(17):3174-3183. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3174
Comparison of endoscopic ultrasound, computed tomography and magnetic resonance imaging in assessment of detailed structures of pancreatic cystic neoplasms 
Chen Du, Ning-Li Chai, En-Qiang Linghu, Hui-Kai Li, Li-Hua Sun, Lei Jiang, Xiang-Dong Wang, Ping Tang, Jing Yang 
World J Gastroenterol 23(17):3184-3192. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3184
Letters To The Editor
Efficacy and safety of stellate ganglion block in chronic ulcerative colitis 
Eugene Lipov, Ken Candido 
World J Gastroenterol 23(17):3193-3194. Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3193