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World J Gastroenterol. May 7, 2017; 23(17): 3133-3141
Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3133
Diagnostic value of gadobenate dimeglumine-enhanced hepatocyte-phase magnetic resonance imaging in evaluating hepatic fibrosis and hepatitis
Xiu-Mei Li, Zhu Chen, En-Hua Xiao, Quan-Liang Shang, Cong Ma
Xiu-Mei Li, Zhu Chen, En-Hua Xiao, Quan-Liang Shang, Cong Ma, Department of Radiology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China
Xiu-Mei Li, Department of Radiology, The First Affiliate Hospital of Fujian Medical University, Fuzhou 350005, Fujian Province, China
Author contributions: Li XM, Chen Z and Xiao EH designed the research; Li XM, Chen Z and Ma C performed the research; Li XM and Shang QL analyzed the data; Li XM wrote the paper.
Supported by National Natural Science Foundation of China, Nos. 81571784 and 81601471; Scientific and Technological Support Project for Social Development of Hunan Province, No. 2015SF2020-4; Project of Development and Reform Commission of Hunan Province, No. Xiang Cai Enterprise Means [2015]83.
Conflict-of-interest statement: We declare that we have no financial and personal relationships with other people or organization that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled, "Diagnostic value of Gd-BOPTA-enhanced magnetic resonance imaging hepatocyte phase in evaluating hepatic fibrosis and hepatitis".
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: En-Hua Xiao, MD, Professor, Department of Radiology, The Second Xiangya Hospital of Central South University, No.139 Ren Min Zhong Lu, Fu Rong District, Changsha 410011, Hunan Province, China. cjr.xiaoenhua@vip.163.com
Telephone: +86-731-85292116
Received: September 22, 2016
Peer-review started: September 23, 2016
First decision: December 19, 2016
Revised: January 16, 2017
Accepted: March 15, 2017
Article in press: March 15, 2017
Published online: May 7, 2017
Core Tip

Core tip: A crucial issue in the prognosis and management of chronic liver diseases is the extent and the progression of hepatic fibrosis. The percutaneous liver biopsy is a widely adopted classical method to diagnose hepatic fibrosis, but it is invasive. We use the degree enhancement in the hepatocyte phase of Gd-BOPTA-enhanced magnetic resonance imaging to evaluate the liver condition of patients with chronic liver diseases. This method is recommended because of advantages such as no injury to the patient and possibility to assess the stage of hepatic fibrosis, the degree of hepatitis and the liver function.