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Open-Access Journal
Editorial
Sphincter of Oddi dysfunction Type III: New studies suggest new approaches are needed 
C Mel Wilcox 
World J Gastroenterol 21(19):5755-5761. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5755
Changes in the esophageal mucosa of patients with non erosive reflux disease: How far have we gone? 
Christos Triantos, Nikolaos Koukias, Georgios Karamanolis, Konstantinos Thomopoulos 
World J Gastroenterol 21(19):5762-5767. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5762
Hepatitis C: New challenges in liver transplantation 
Tajana Filipec Kanizaj, Nino Kunac 
World J Gastroenterol 21(19):5768-5777. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5768
Review
Gastric cancer and the epoch of immunotherapy approaches 
Elena Niccolai, Antonio Taddei, Domenico Prisco, Amedeo Amedei 
World J Gastroenterol 21(19):5778-5793. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5778
Incidence and treatment of brain metastasis in patients with esophageal carcinoma 
Wei Feng, Peng Zhang, Xiao Zheng, Ming Chen, Wei-Min Mao 
World J Gastroenterol 21(19):5805-5812. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5805
Minireviews
Liver involvement in pediatric celiac disease 
Caterina Anania, Ester De Luca, Giovanna De Castro, Claudio Chiesa, Lucia Pacifico 
World J Gastroenterol 21(19):5813-5822. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5813
Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease 
Cristina-Sorina Cătană, Ioana Berindan-Neagoe, Vasile Cozma, Cristian Magdaş, Flaviu Tăbăran, Dan Lucian Dumitraşcu 
World J Gastroenterol 21(19):5823-5830. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5823
Basic Study
Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA 
Hye Rim Cho, Youkyung Lee, Philip Doble, David Bishop, Dominic Hare, Young-Jae Kim, Kwang Gi Kim, Hye Seung Jung, Kyong Soo Park, Seung Hong Choi, Woo Kyung Moon 
World J Gastroenterol 21(19):5831-5842. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5831
Expression profile of microRNAs in gastrointestinal stromal tumors revealed by high throughput quantitative RT-PCR microarray 
Han-Xing Tong, Yu-Hong Zhou, Ying-Yong Hou, Yong Zhang, Yuan Huang, Bin Xie, Jiong-Yuan Wang, Quan Jiang, Jun-Yi He, Ye-Bo Shao, Wu-Mei Han, Ruo-Ying Tan, Jun Zhu, Wei-Qi Lu 
World J Gastroenterol 21(19):5843-5855. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5843
Hepatocyte nuclear factor 4α induces a tendency of differentiation and activation of rat hepatic stellate cells 
Kai Liu, Ming-Gao Guo, Xiao-Li Lou, Xiao-Ya Li, Yang Xu, Wei-Dan Ji, Xuan-Dong Huang, Jia-He Yang, Ji-Cheng Duan 
World J Gastroenterol 21(19):5856-5866. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5856
MiR-451 inhibits proliferation of esophageal carcinoma cell line EC9706 by targeting CDKN2D and MAP3K1 
Wen-Qiao Zang, Xuan Yang, Tao Wang, Yuan-Yuan Wang, Yu-Wen Du, Xiao-Nan Chen, Min Li, Guo-Qiang Zhao 
World J Gastroenterol 21(19):5867-5876. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5867
Effect of nuclear factor-κB and angiotensin II receptor type 1 on the pathogenesis of rat non-alcoholic fatty liver disease 
Dao-Yu Tan, Hai-Yan Shi, Chang-Ping Li, Xiao-Ling Zhong, Ming Kang 
World J Gastroenterol 21(19):5877-5883. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5877
Effect of microRNA-1 on hepatocellular carcinoma tumor endothelial cells 
Chao Hu, Shi-Qiang Shen, Zhong-Hui Cui, Zu-Bing Chen, Wei Li 
World J Gastroenterol 21(19):5884-5892. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5884
Retrospective Cohort Study
Validation of aspartate aminotransferase to platelet ratio for diagnosis of liver fibrosis and prediction of postoperative prognosis in infants with biliary atresia 
Li-Yuan Yang, Jie Fu, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Zheng-Rong Chen, Li-Juan He, Zhe Wen, Hui Wang, Le Li, Feng-Hua Wang, Jia-Kang Yu, Yi Xu, Si-Tang Gong, Hui-Min Xia, Hai-Ying Liu 
World J Gastroenterol 21(19):5893-5900. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5893
Retrospective Study
Prognostic value and clinical correlations of 18-fluorodeoxyglucose metabolism quantifiers in gastric cancer 
Kinga Grabinska, Maciej Pelak, Jerzy Wydmanski, Andrzej Tukiendorf, Andrea d’Amico 
World J Gastroenterol 21(19):5901-5909. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5901
Risk factors causing structural sequelae after anastomotic leakage in mid to low rectal cancer 
Woong Bae Ji, Jung Myun Kwak, Jin Kim, Jun Won Um, Seon Hahn Kim 
World J Gastroenterol 21(19):5910-5917. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5910
Needle-knife fistulotomy vs double-guidewire technique in patients with repetitive unintentional pancreatic cannulations 
Su Jin Kim, Dae Hwan Kang, Hyung Wook Kim, Cheol Woong Choi, Su Bum Park, Byeong Jun Song, Young Mi Hong 
World J Gastroenterol 21(19):5918-5925. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5918
Risk scoring system and predictor for clinically relevant pancreatic fistula after pancreaticoduodenectomy 
Ji-Ye Chen, Jian Feng, Xian-Qiang Wang, Shou-Wang Cai, Jia-Hong Dong, Yong-Liang Chen 
World J Gastroenterol 21(19):5926-5933. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5926
Factors associated with early recurrence after curative surgery for gastric cancer 
Wei-Ming Kang, Qing-Bin Meng, Jian-Chun Yu, Zhi-Qiang Ma, Zhi-Tian Li 
World J Gastroenterol 21(19):5934-5940. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5934
Laparoscopic vs computerized tomography-guided radiofrequency ablation for large hepatic hemangiomas abutting the diaphragm 
Jun Gao, Jian Kong, Xue-Mei Ding, Shan Ke, Hai-Gang Niu, Zong-Hai Xin, Chun-Min Ning, Shi-Gang Guo, Xiao-Long Li, Long Zhang, Yong-Hong Dong, Wen-Bing Sun 
World J Gastroenterol 21(19):5941-5949. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5941
Endoscopic treatment for pancreatic diseases: Needle-knife-guided cannulation via the minor papilla 
Wei Wang, Biao Gong, Wei-Song Jiang, Lei Liu, Kouken Bielike, Bin Xv, Yun-Lin Wu 
World J Gastroenterol 21(19):5950-5960. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5950
Novel immunological and nutritional-based prognostic index for gastric cancer 
Kai-Yu Sun, Jian-Bo Xu, Shu-Ling Chen, Yu-Jie Yuan, Hui Wu, Jian-Jun Peng, Chuang-Qi Chen, Pi Guo, Yuan-Tao Hao, Yu-Long He 
World J Gastroenterol 21(19):5961-5971. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5961
Clinicopathologic features of remnant gastric cancer over time following distal gastrectomy 
De-Wei Zhang, Biao Dong, Zhen Li, Dong-Qiu Dai 
World J Gastroenterol 21(19):5972-5978. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5972
Clinical Trials Study
Phase I trial of combination chemotherapy with gemcitabine, cisplatin, and S-1 in patients with advanced biliary tract cancer 
Akinori Watanabe, Mitsuhiro Kida, Shiro Miyazawa, Tomohisa Iwai, Kosuke Okuwaki, Toru Kaneko, Hiroshi Yamauchi, Miyoko Takezawa, Hiroshi Imaizumi, Wasaburo Koizumi 
World J Gastroenterol 21(19):5979-5984. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5979
Randomized Clinical Trial
Effectiveness of probiotic therapy for the prevention of relapse in patients with inactive ulcerative colitis 
Yasushi Yoshimatsu, Akihiro Yamada, Ryuichi Furukawa, Koji Sono, Aisaku Osamura, Kentaro Nakamura, Hiroshi Aoki, Yukiko Tsuda, Nobuo Hosoe, Nobuo Takada, Yasuo Suzuki 
World J Gastroenterol 21(19):5985-5994. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5985
Efficacy and safety of a patient-positioning device (EZ-FIX) for endoscopic retrograde cholangiopancreatography 
Seungho Lee, Joung-Ho Han, Hee Seung Lee, Ki Bae Kim, In-kwang Lee, Eun-Jong Cha, Young Duck Shin, Namgyu Park, Seon Mee Park 
World J Gastroenterol 21(19):5995-6000. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5995
Prospective Study
Assessment of disease specific knowledge and health-related quality of life among United States military veterans with inflammatory bowel disease 
Jason K Hou, Joshua A Turkeltaub, Thomas R McCarty III, Hashem B El-Serag 
World J Gastroenterol 21(19):6001-6007. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6001
Risk of venous congestion in live donors of extended right liver graft 
Arnold Radtke, George Sgourakis, Ernesto P Molmenti, Susanne Beckebaum, Vito R Cicinnati, Hartmut Schmidt, Heinz-Otto Peitgen, Christoph E Broelsch, Massimo Malagó, Tobias Schroeder 
World J Gastroenterol 21(19):6008-6017. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6008
Vascular endothelial growth factor and tryptase changes after chemoembolization in hepatocarcinoma patients 
Girolamo Ranieri, Michele Ammendola, Ilaria Marech, Annamaria Laterza, Ines Abbate, Caroline Oakley, Angelo Vacca, Rosario Sacco, Cosmo Damiano Gadaleta 
World J Gastroenterol 21(19):6018-6025. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6018
Meta-Analysis
Association of type 2 diabetes mellitus and the risk of colorectal cancer: A meta-analysis and systematic review 
Salman Yousuf Guraya 
World J Gastroenterol 21(19):6026-6031. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6026
Endoscopic submucosal dissection for early gastric cancer with undifferentiated-type histology: A meta-analysis 
Chang Seok Bang, Gwang Ho Baik, In Soo Shin, Jing Bong Kim, Ki Tae Suk, Jai Hoon Yoon, Yeon Soo Kim, Dong Joon Kim, Woon Geon Shin, Kyung Ho Kim, Hak Yang Kim, Hyun Lim, Ho Seok Kang, Jong Hyeok Kim, Jin Bae Kim, Sung Won Jung, Sea Hyub Kae, Hyun Joo Jang, Min Ho Choi 
World J Gastroenterol 21(19):6032-6043. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6032
Infliximab is superior to other biological agents for treatment of active ulcerative colitis: A meta-analysis 
Wei-Qun Mei, Hui-Zhen Hu, Ying Liu, Zhi-Chen Li, Wei-Guo Wang 
World J Gastroenterol 21(19):6044-6051. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6044
Associations between CD24 gene polymorphisms and inflammatory bowel disease: A meta-analysis 
Xiao-Li Huang, Dong-Hua Xu, Guo-Pin Wang, Shu Zhang, Cheng-Gong Yu 
World J Gastroenterol 21(19):6052-6059. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6052
Case Report
Fulminant ulcerative colitis in a healthy pregnant woman 
Rossana Orabona, Adriana Valcamonico, Marianna Salemme, Stefania Manenti, Guido AM Tiberio, Tiziana Frusca 
World J Gastroenterol 21(19):6060-6064. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6060
Fecal stream diversion and mucosal cytokine levels in collagenous colitis: A case report 
Niki Daferera, Ashok Kumar Kumawat, Elisabeth Hultgren-Hörnquist, Simone Ignatova, Magnus Ström, Andreas Münch 
World J Gastroenterol 21(19):6065-6071. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6065
Epstein Barr virus-positive mucocutaneous ulcer of the colon associated Hodgkin lymphoma in Crohn’s disease 
Neil R Moran, Bradley Webster, Kenneth M Lee, Judith Trotman, Yiu-Lam Kwan, John Napoli, Rupert W Leong 
World J Gastroenterol 21(19):6072-6076. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6072
Surgical repair of intractable chylous ascites following laparoscopic anterior resection 
Gi Won Ha, Min Ro Lee 
World J Gastroenterol 21(19):6077-6081. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6077
Severe Henoch-Schönlein purpura with infliximab for ulcerative colitis 
Yang Song, Yan-Hong Shi, Chong He, Chang-Qin Liu, Jun-Shan Wang, Yu-Jie Zhao, Yan-Min Guo, Rui-Jin Wu, Xiao-Yue Feng, Zhan-Ju Liu 
World J Gastroenterol 21(19):6082-6087. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6082
Primary hepatic angiosarcoma: A report of two cases and literature review 
Yi-Ping Zhu, Yan-Min Chen, Erik Matro, Ren-Biao Chen, Zhi-Nong Jiang, Yi-Ping Mou, Hong-Jie Hu, Chao-Jie Huang, Guan-Yu Wang 
World J Gastroenterol 21(19):6088-6096. Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.6088