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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2015; 21(19): 5934-5940
Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5934
Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5934
Factors associated with early recurrence after curative surgery for gastric cancer
Wei-Ming Kang, Jian-Chun Yu, Zhi-Qiang Ma, Zhi-Tian Li, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China
Qing-Bin Meng, Department of Gastrointestinal Surgery, First Hospital of Wuhan City, Wuhan 430022, Hubei Provence, China
Author contributions: Kang WM and Meng QB contributed equally to this work both as the first author; Kang WM, Meng QB and Yu JC designed the research; Kang WM, Meng QB and Ma ZQ performed the research; Yu JC, Ma ZQ and Li ZT analyzed the data; Kang WM, Meng QB and Li ZT wrote the paper.
Supported by the Beijing Municipal Natural Science Foundation, No. 7132209; Capital Health Research and Development Special Fund, No. 2014-3-4014; Hubei Province Health and Family Planning Scientific Research Project, No. WJ2015MB137; Wuhan City Medical Research Project, No. WX15B14.
Ethics approval: The study was reviewed and approved by the Ethics Committee of Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: The authors have no conflicts of interest to declare.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jian-Chun Yu, MD, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, No. 1 Shuai Fu Yuan, Dongcheng District, Beijing 100730, China. yu-jch@163.com
Telephone: +86-10-69152213 Fax: +86-10-69152213
Received: November 2, 2014
Peer-review started: November 2, 2014
First decision: November 27, 2014
Revised: January 7, 2015
Accepted: February 5, 2015
Article in press: February 5, 2015
Published online: May 21, 2015
Peer-review started: November 2, 2014
First decision: November 27, 2014
Revised: January 7, 2015
Accepted: February 5, 2015
Article in press: February 5, 2015
Published online: May 21, 2015
Core Tip
Core tip: Few studies have assessed recurrence patterns or predictors of early recurrence after curative surgery in Chinese patients with gastric carcinoma. This study found that survival after gastric cancer recurrence was poor. Large tumor size and advanced pN stage were associated with early recurrence of tumor pT1 stage tumors. Age, pT stage, pN stage, Lauren histotype, lymphovascular invasion, intraoperative chemotherapy, and postoperative chemotherapy were independent predictors of early recurrence of pT2-4a stage tumors.