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Open-Access Journal
Review
Diverticular disease of the colon: New perspectives in symptom development and treatment 
Antonio Colecchia, Lorenza Sandri, Simona Capodicasa, Amanda Vestito, Giuseppe Mazzella, Tommaso Staniscia, Enrico Roda, Davide Festi 
World J Gastroenterol 9(7):1385-1389. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1385
Esophageal Cancer
NQO1 C609T polymorphism associated with esophageal cancer and gastric cardiac carcinoma in North China 
Jian-Hui Zhang, Yan Li, Rui Wang, Helen Geddert, Wei Guo, Deng-Gui Wen, Zhi-Feng Chen, Li-Zhen Wei, Gang Kuang, Ming He, Li-Wei Zhang, Ming-Li Wu, Shi-Jie Wang 
World J Gastroenterol 9(7):1390-1393. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1390
CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: Study of population from a high- incidence area in north China 
Li-Dong Wang, Shu Zheng, Bin Liu, Jian-Xiang Zhou, Yan-Jie Li, Ji-Xue Li 
World J Gastroenterol 9(7):1394-1397. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1394
Gastric Cancer
Carbonic anhydrase isozymes IX and XII in gastric tumors 
Mari Leppilampi, Juha Saarnio, Tuomo J. Karttunen, Jyrki Kivelä, Silvia Pastoreková, Jaromir Pastorek, Abdul Waheed, William S. Sly, Seppo Parkkila 
World J Gastroenterol 9(7):1398-1403. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1398
Spiral CT in gastric carcinoma: Comparison with barium study, fiberoptic gastroscopy and histopathology 
Feng Chen, Yi-Cheng Ni, Kai-Er Zheng, Sheng-Hong Ju, Jun Sun, Xi-Long Ou, Man-Hua Xu, Hao Zhang, Guy Marchal 
World J Gastroenterol 9(7):1404-1408. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1404
Association of VCAM-1 overexpression with oncogenesis, tumor angiogenesis and metastasis of gastric carcinoma 
Yong-Bin Ding, Guo-Yu Chen, Jian-Guo Xia, Xi-Wei Zang, Hong-Yu Yang, Li Yang 
World J Gastroenterol 9(7):1409-1414. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1409
Expression of Fas ligand and Caspase-3 contributes to formation of immune escape in gastric cancer 
Hua-Chuan Zheng, Jin-Min Sun, Zheng-Li Wei, Xue-Fei Yang, Yin-Chang Zhang, Yan Xin 
World J Gastroenterol 9(7):1415-1420. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1415
Prognostic significance of expression of cyclooxygenase-2 and vascular endothelial growth factor in human gastric carcinoma 
Hai Shi, Jian-Ming Xu, Nai-Zhong Hu, Hui-Jun Xie 
World J Gastroenterol 9(7):1421-1426. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1421
Preventive effect of hydrotalcite on gastric mucosal injury in rats induced by taurocholate 
Bao-Ping Yu, Jun Sun, Mu-Qi Li, He-Sheng Luo, Jie-Ping Yu 
World J Gastroenterol 9(7):1427-1430. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1427
Expression of NGF family and their receptors in gastric carcinoma: A cDNA microarray study 
Jian-Jun Du, Ke-Feng Dou, Shu-You Peng, Bing-Zhi Qian, Hua-Sheng Xiao, Feng Liu, Wei-Zhong Wang, Wen-Xian Guan, Zhi-Qing Gao, Ying-Bin Liu, Ze-Guang Han 
World J Gastroenterol 9(7):1431-1434. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1431
Expression of survivin in human gastric carcinoma and gastric carcinoma model of rats 
Xiao-Dong Zhu, Geng-Jin Lin, Li-Ping Qian, Zhong-Qing Chen 
World J Gastroenterol 9(7):1435-1438. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1435
cDNA suppression subtraction library for screening down-regulated genes in gastric carcinoma 
Jian-Jun Du, Ke-Feng Dou, Shu-You Peng, Hua-Sheng Xiao, Wei-Zhong Wang, Wen-Xian Guan, Zhong-Hua Wang, Zhi-Qing Gao, Ying-Bin Liu 
World J Gastroenterol 9(7):1439-1443. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1439
Liver Cancer
Observation of DNA damage of human hepatoma cells irradiated by heavy ions using comet assay 
Li-Mei Qiu, Wen-Jian Li, Xin-Yue Pang, Qing-Xiang Gao, Yan Feng, Li-Bin Zhou, Gao-Hua Zhang 
World J Gastroenterol 9(7):1450-1454. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1450
Preparation and characterization of polyclonal antibodies against ARL-1 protein 
Jun-Fei Jin, Liu-Di Yuan, Li Liu, Zhu-Jiang Zhao, Wei Xie 
World J Gastroenterol 9(7):1455-1459. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1455
Characteristics and application of established luciferase hepatoma cell line that responds to dioxin-like chemicals 
Zhi-Ren Zhang, Shun-Qing Xu, Xi Sun, Yong-Jun Xu, Xiao-Kun Cai, Zhi-Wei Liu, Xiang-Lin Tan, Yi-Kai Zhou, Jun-Yue Zhang, Hong Yan 
World J Gastroenterol 9(7):1460-1464. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1460
Construction and expression of recombined human AFP eukaryotic expression vector 
Li-Wang Zhang, Jun Ren, Liang Zhang, Hong-Mei Zhang, Bin Jin, Bo-Rong Pan, Xiao-Ming Si, Yan-Jun Zhang, Zhong-Hua Wang, Yang-Lin Pan, Stephen M Festein 
World J Gastroenterol 9(7):1465-1468. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1465
Mast cells and human hepatocellular carcinoma 
Fabio Grizzi, Barbara Franceschini, Maurizio Chiriva-Internati, Young Liu, Paul L. Hermonat, Nicola Dioguardi 
World J Gastroenterol 9(7):1469-1473. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1469
Antitumor and immunomodulatory activity of resveratrol on experimentally implanted tumor of H22 in Balb/c mice 
Hong-Shan Liu, Cheng-En Pan, Wei Yang, Xue-Min Liu 
World J Gastroenterol 9(7):1474-1476. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1474
Colorectal Cancer
Laparoscopic total mesorectal excision of low rectal cancer with preservation of anal sphincter: A report of 82 cases 
Zong-Guang Zhou, Zhao Wang, Yong-Yang Yu, Ye Shu, Zhong Cheng, Li Li, Wen-Zhang Lei, Tian-Cai Wang 
World J Gastroenterol 9(7):1477-1481. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1477
Expression of proliferating cell nuclear antigen and CD44 variant exon 6 in primary tumors and corresponding lymph node metastases of colorectal carcinoma with Dukes' stage C or D 
Ji-Cheng Zhang, Zuo-Ren Wang, Yan-Juan Cheng, Ding-Zhong Yang, Jing-Sen Shi, Ai-Lin Liang, Ning-Na Liu, Xiao-Min Wang 
World J Gastroenterol 9(7):1482-1486. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1482
Viral Hepatitis
Gastric autoimmune disorders in patients with chronic hepatitis C before, during and after interferon-alpha therapy 
Carlo Fabbri, M. Francesca Jaboli, Silvia Giovanelli, Francesco Azzaroli, Alessandro Pezzoli, Esterita Accogli, Stefania Liva, Giovanni Nigro, Anna Miracolo, Davide Festi, Antonio Colecchia, Marco Montagnani, Enrico Roda, Giuseppe Mazzella 
World J Gastroenterol 9(7):1487-1490. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1487
Long-term alpha interferon and lamivudine combination therapy in non-responder patients with anti-HBe-positive chronic hepatitis B: Results of an open, controlled trial 
M. Francesca Jaboli, Carlo Fabbri, Stefania Liva, Francesco Azzaroli, Giovanni Nigro, Silvia Giovanelli, Francesco Ferrara, Anna Miracolo, Sabrina Marchetto, Marco Montagnani, Antonio Colecchia, Davide Festi, Letizia Bacchi Reggiani, Enrico Roda, Giuseppe Mazzella 
World J Gastroenterol 9(7):1491-1495. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1491
Acute hepatitis C in a chronically HIV-infected patient: Evolution of different viral genomic regions 
Diego Flichman, Veronica Kott, Silvia Sookoian, Rodolfo Campos 
World J Gastroenterol 9(7):1496-1500. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1496
Interruption of HBV intrauterine transmission: A clinical study 
Xiao-Mao Li, Yue-Bo Yang, Hong-Ying Hou, Zhong-Jie Shi, Hui-Min Shen, Ben-Qi Teng, Ai-Min Li, Min-Feng Shi, Ling Zou 
World J Gastroenterol 9(7):1501-1503. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1501
Inhibition of HBV targeted ribonuclease enhanced by introduction of linker 
Wei-Dong Gong, Jun Liu, Jin Ding, Ya Zhao, Ying-Hui Li, Cai-Fang Xue 
World J Gastroenterol 9(7):1504-1507. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1504
Detection of anti-HAV antibody with dot immunogold filtration assay 
Zhong-Jun Shao, De-Zhong Xu, Yong-Ping Yan, Jing-Hua Li, Jing-Xia Zhang, Zhi-Ying Zhang, Bo-Rong Pan 
World J Gastroenterol 9(7):1508-1511. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1508
Generation of cytotoxic T cell against HBcAg using retrovirally transduced dendritic cells 
Chuan-Lin Ding, Kun Yao, Tian-Tai Zhang, Feng Zhou, Lin Xu, Jiang-Ying Xu 
World J Gastroenterol 9(7):1512-1515. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1512
A novel stop codon mutation in HBsAg gene identified in a hepatitis B virus strain associated with cryptogenic cirrhosis 
Xu Yang, Xiao-Peng Tang, Jian-Hua Lei, Hong-Yu Luo, Yong-Hong Zhang 
World J Gastroenterol 9(7):1516-1520. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1516
Aggregate formation of hepatitis B virus X protein affects cell cycle and apoptosis 
Chang-Zheng Song, Zeng-Liang Bai, Chang-Cheng Song, Qing-Wei Wang 
World J Gastroenterol 9(7):1521-1524. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1521
Anti-HBV effect of TAT- HBV targeted ribonuclease 
Jin Ding, Jun Liu, Cai-Fang Xue, Wei-Dong Gong, Ying-Hui Li, Ya Zhao 
World J Gastroenterol 9(7):1525-1528. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1525
H. Pylori
Construction of hpaA gene from a clinical isolate of Helicobacter pylori and identification of fusion protein 
Ya-Fei Mao, Jie Yan, Li-Wei Li, Shu-Ping Li 
World J Gastroenterol 9(7):1529-1536. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1529
Density of Helicobacter pylori may affect the efficacy of eradication therapy and ulcer healing in patients with active duodenal ulcers 
Yung-Chih Lai, Teh-Hong Wang, Shih-Hung Huang, Sien-Sing Yang, Chi-Hwa Wu, Tzen-Kwan Chen, Chia-Long Lee 
World J Gastroenterol 9(7):1537-1540. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1537
Basic Research
Polymorphism in transmembrane region of MICA gene and cholelithiasis 
Shou-Chuan Shih, Yann-Jinn Lee, Hsin-Fu Liu, Ching-Wen Dang, Shih-Chuan Chang, Shee-Chan Lin, Chin-Roa Kao 
World J Gastroenterol 9(7):1541-1544. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1541
Improvements of postburn renal function by early enteral feeding and their possible mechanisms in rats 
Li Zhu, Zong-Cheng Yang, De-Chang Chen 
World J Gastroenterol 9(7):1545-1549. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1545
Application of modified two-cuff technique and multiglycosides tripterygium wilfordii in hamster-to-rat liver xenotransplant model 
Hua Guo, Yi-Jun Wu, Shu-Sen Zheng, Wei-Lin Wang, Jun Yu 
World J Gastroenterol 9(7):1550-1553. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1550
Expression of metallothionein gene at different time in testicular interstitial cells and liver of rats treated with cadmium 
Xu-Yi Ren, Yong Zhou, Jian-Peng Zhang, Wei-Hua Feng, Bing-Hua Jiao 
World J Gastroenterol 9(7):1554-1558. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1554
Effect of compound rhodiola sachalinensis A Bor on CCl4-induced liver fibrosis in rats and its probable molecular mechanisms 
Xiao-Ling Wu, Wei-Zheng Zeng, Pi-Long Wang, Chun-Tao Lei, Ming-De Jiang, Xiao-Bin Chen, Yong Zhang, Hui Xu, Zhao Wang 
World J Gastroenterol 9(7):1559-1562. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1559
Effect of tetramethylpyrazine on P-selectin and hepatic/renal ischemia and reperfusion injury in rats 
Jin-Lian Chen, Tong Zhou, Wei-Xiong Chen, Jin-Shui Zhu, Ni-Wei Chen, Ming-Jun Zhang, Yun-Lin Wu 
World J Gastroenterol 9(7):1563-1566. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1563
Role of NF-κB and cytokine in experimental cancer cachexia 
Wei Zhou, Zhi-Wei Jiang, Jie Tian, Jun Jiang, Ning Li, Jie-Shou Li 
World J Gastroenterol 9(7):1567-1570. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1567
Maxizyme-mediated specific inhibition on mutant-type p53 in vitro 
Xin-Juan Kong, Yu-Hu Song, Ju-Sheng Lin, Huan-Jun Huang, Nan-Xia Wang, Nan-Zhi Liu, Bin Li, You-Xin Jin 
World J Gastroenterol 9(7):1571-1575. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1571
Clinical Research
High level of deoxycholic acid in human bile does not promote cholesterol gallstone formation 
Ulf Gustafsson, Staffan Sahlin, Curt Einarsson 
World J Gastroenterol 9(7):1576-1579. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1576
Association of CagA and VacA presence with ulcer and non-ulcer dyspepsia in a Turkish population 
Kantarceken Bulent, Aladag Murat, Atik Esin, Koksal Fatih, Harputluoglu MMMurat, Harputluoglu Hakan, Karincaoglu Melih, Ates Mehmet, Yildirim Bulent, Hilmioglu Fatih 
World J Gastroenterol 9(7):1580-1583. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1580
Expression of local renin and angiotensinogen mRNA in cirrhotic portal hypertensive patient 
Li Zhang, Zhen Yang, Bao-Min Shi, Da-Peng Li, Chong-Yun Fang, Fa-Zu Qiu 
World J Gastroenterol 9(7):1584-1588. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1584
Brief Reports
Biliary carcinoembryonic antigen levels in diagnosis of occult hepatic metastases from colorectal carcinoma 
Jaques Waisberg, Rogério T. Palma, Luís Contim Neto, Lourdes C. Martins, Maurício S. L. Oliveira, Carlos A. Nagashima, Antonio C. Godoy, Fabio S. Goffi 
World J Gastroenterol 9(7):1589-1593. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1589
Effects of carbon dioxide and nitrogen on adhesive growth and expressions of E-cadherin and VEGF of human colon cancer cell CCL-228 
Kai-Lin Cai, Guo-Bing Wang, Li-Juan Xiong 
World J Gastroenterol 9(7):1594-1597. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1594
Meta analysis of risk factors for colorectal cancer 
Kun Chen, Jiong-Liang Qiu, Yang Zhang, Yu-Wan Zhao 
World J Gastroenterol 9(7):1598-1600. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1598
Expressions of PCNA, p53, p21WAF-1 and cell proliferation in fetal esophageal epithelia: Comparative study with adult esophageal lesions from subjects at high-incidence area for esophageal cancer in Henan, North China 
Ying Xing, Yu Ning, Li-Qiang Ru, Li-Dong Wang 
World J Gastroenterol 9(7):1601-1603. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1601
Vascular endothelial growth factor and microvascular density in esophageal and gastric carcinomas 
Jin-Rong Du, Ying Jiang, Yan-Mei Zhang, Hong Fu 
World J Gastroenterol 9(7):1604-1606. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1604
Effect of P-selectin monoclonal antibody on metastasis of gastric cancer and immune function 
Jin-Lian Chen, Wei-Xiong Chen, Jin-Shui Zhu, Ni-Wei Chen, Tong Zhou, Ming Yao, Dong-Qing Zhang, Yun-Lin Wu 
World J Gastroenterol 9(7):1607-1610. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1607
Effects of heparin on liver fibrosis in patients with chronic hepatitis B 
Jun Shi, Jing-Hua Hao, Wan-Hua Ren, Ju-Ren Zhu 
World J Gastroenterol 9(7):1611-1614. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1611
Effect of Sea buckthorn on liver fibrosis: A clinical study 
Ze-Li Gao, Xiao-Hong Gu, Feng-Tao Cheng, Fo-Hu Jiang 
World J Gastroenterol 9(7):1615-1617. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1615
Fatty metamorphosis of the liver in patients with breast cancer: Possible associated factors 
Cheng-Hsin Chu, Shee-Chan Lin, Shou-Chuan Shih, Chin-Roa Kao, Sun-Yen Chou 
World J Gastroenterol 9(7):1618-1620. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1618
Diarrhea and acaroid mites: A clinical study 
Chao-Pin Li, Yu-Bao Cui, Jian Wang, Qing-Gui Yang, Ye Tian 
World J Gastroenterol 9(7):1621-1624. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1621
Modified technique for combined liver-small bowel transplantation in pigs 
Zhen-Yu Yin, Xiao-Dong Ni, Feng Jiang, Ning Li, You-Sheng Li, Jie-Shou Li 
World J Gastroenterol 9(7):1625-1628. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1625
In vitro assay for HCV serine proteinase expressed in insect cells 
Li-Hua Hou, Gui-Xin Du, Rong-Bin Guan, Yi-Gang Tong, Hai-Tao Wang 
World J Gastroenterol 9(7):1629-1632. Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1629