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Open-Access Journal
Editorial
Intragastric injection of botulinum toxin for the treatment of obesity. Where are we? 
Diego Garcia-Compean, Hector Maldonado Garza 
World J Gastroenterol 14(12):1805-1809. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1805
Observer
Colorectal cancer risk in Crohn’s disease 
Hugh James Freeman 
World J Gastroenterol 14(12):1810-1811. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1810
Review
Role of chemotherapy and novel biological agents in the treatment of elderly patients with colorectal cancer 
Gerardo Rosati, Domenico Bilancia 
World J Gastroenterol 14(12):1812-1822. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1812
Crosstalk between tumor cells and microenvironment via Wnt pathway in colorectal cancer dissemination 
Dan Huang, Xiang Du 
World J Gastroenterol 14(12):1823-1827. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1823
Esophageal Cancer
Comparative genomic hybridization analysis of genetic aberrations associated with development of esophageal squamous cell carcinoma in Henan, China 
Yan-Ru Qin, Li-Dong Wang, Zong-Min Fan, Dora Kwong, Xin-Yuan Guan 
World J Gastroenterol 14(12):1828-1835. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1828
Viral Hepatitis
Effects of two novel nucleoside analogues on different hepatitis B virus promoters 
Xing-Xing He, Ju-Sheng Lin, Ying Chang, Ying-Hui Zhang, Yan Li, Xiao-Yan Wang, Dong Xu, Xiao-Ming Cheng 
World J Gastroenterol 14(12):1836-1841. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1836
Basic Research
Immune-mediated anti-neoplastic effect of intratumoral RSV envelope glycoprotein expression is related to apoptotic death of tumor cells but not to the size of syncytia 
Dennis Hoffmann, Thomas Grunwald, Wibke Bayer, Oliver Wildner 
World J Gastroenterol 14(12):1842-1850. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1842
Effect of JIANPI HUOXUE decoction on inflammatory cytokine secretion pathway in rat liver with lipopolysaccharide challenge 
Jing-Hua Peng, Yi-Yang Hu, Yang Cheng, Chong Han, Li-Li Xu, Qin Feng, Shao-Dong Chen, Qing Tao, Hong-Shan Li, Xue-Mei Li 
World J Gastroenterol 14(12):1851-1857. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1851
Over-expressed and truncated midkines promote proliferation of BGC823 cells in vitro and tumor growth in vivo 
Qing-Ling Wang, Hui Wang, Shu-Li Zhao, Ya-Hong Huang, Ya-Yi Hou 
World J Gastroenterol 14(12):1858-1865. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1858
Clinical Research
Clinical and endoscopic features of Chinese reflux esophagitis patients 
Wei Li, Shu-Tian Zhang, Zhong-Lin Yu 
World J Gastroenterol 14(12):1866-1871. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1866
Cost-effectiveness analysis of early veno-venous hemofiltration for severe acute pancreatitis in China 
Kun Jiang, Xin-Zu Chen, Qing Xia, Wen-Fu Tang, Lei Wang 
World J Gastroenterol 14(12):1872-1877. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1872
Rapid Communication
Factors influencing a low rate of hepatitis C viral RNA clearance in heroin users from Southern China 
Rebecca J Garten, Sheng-Han Lai, Jin-Bing Zhang, Wei Liu, Jie Chen, Xiao-Fang Yu 
World J Gastroenterol 14(12):1878-1884. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1878
Effect of infliximab on small bowel stenoses in patients with Crohn’s disease 
Nadia Pallotta, Fausto Barberani, Naima Abdulkadir Hassan, Danila Guagnozzi, Giuseppina Vincoli, Enrico Corazziari 
World J Gastroenterol 14(12):1885-1890. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1885
KIT exon 11 codon 557/558 deletion/insertion mutations define a subset of gastrointestinal stromal tumors with malignant potential 
Katerina Kontogianni-Katsarou, Euthimios Dimitriadis, Constantina Lariou, Evi Kairi-Vassilatou, Nikolaos Pandis, Agatha Kondi-Paphiti 
World J Gastroenterol 14(12):1891-1897. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1891
Portal hemodynamics as predictors of high risk esophageal varices in cirrhotic patients 
Mohammad K Tarzamni, Mohammad H Somi, Sara Farhang, Morteza Jalilvand 
World J Gastroenterol 14(12):1898-1902. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1898
Importance of the surrounding colonic mucosa in distinguishing between hyperplastic and adenomatous polyps during acetic acid chromoendoscopy 
Jeong Hwan Kim, Sun-Young Lee, Byung Kook Kim, Won Hyeok Choe, So Young Kwon, In-Kyung Sung, Hyung-Seok Park, Choon-Jo Jin 
World J Gastroenterol 14(12):1903-1907. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1903
Hemodynamic effects of propranolol with spironolactone in patients with variceal bleeds: A randomized controlled trial 
Binay K De, Deep Dutta, Rimi Som, Pranab K Biswas, Subrata K Pal, Anirban Biswas 
World J Gastroenterol 14(12):1908-1913. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1908
Effect of H pylori infection and its eradication on hyperammo-nemia and hepatic encephalopathy in cirrhotic patients 
Shu-Jie Chen, Liang-Jing Wang, Qin Zhu, Jian-Ting Cai, Tao Chen, Jian-Min Si 
World J Gastroenterol 14(12):1914-1918. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1914
Changes of ghrelin following oral glucose tolerance test in obese children with insulin resistance 
Xiu-Min Wang, You-Jun Jiang, Li Liang, Li-Zhong Du 
World J Gastroenterol 14(12):1919-1924. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1919
Comparative analysis of common CFTR polymorphisms poly-T, TG-repeats and M470V in a healthy Chinese population 
Qin Huang, Wei Ding, Mu-Xin Wei 
World J Gastroenterol 14(12):1925-1930. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1925
Prognostic significance of S100A4 and vascular endothelial growth factor expression in pancreatic cancer 
Kai-Xing Ai, Lin-Yuan Lu, Xin-Yu Huang, Wei Chen, Hui-Zhen Zhang 
World J Gastroenterol 14(12):1931-1935. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1931
Double-balloon enteroscopy reliably directs surgical intervention for patients with small intestinal bleeding 
Mou-Bin Lin, Lu Yin, Jian-Wen Li, Wei-Guo Hu, Qian-Jian Qian 
World J Gastroenterol 14(12):1936-1940. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1936
Comparison of esomeprazole enteric-coated capsules vs esomeprazole magnesium in the treatment of active duodenal ulcer: A randomized, double-blind, controlled study 
Xiao-Yan Liang, Qing Gao, Neng-Ping Gong, Li-Ping Tang, Pi-Long Wang, Xiao-Hong Tao 
World J Gastroenterol 14(12):1941-1945. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1941
Case Report
Investigation of the excluded stomach after Roux-en-Y gastric bypass: The role of percutaneous endoscopy 
Kanwar RS Gill, J Mark McKinney, Mark E Stark, Ernest P Bouras 
World J Gastroenterol 14(12):1946-1948. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1946
Conservative management of perforated duodenal diverticulum: A case report and review of the literature 
David Martínez-Cecilia, Alvaro Arjona-Sánchez, Manuel Gómez-Álvarez, Eva Torres-Tordera, Antonio Luque-Molina, Victor Valentí-Azcárate, Javier Briceño-Delgado, Francisco-Javier Padillo, Pedro López-Cillero, Sebastián Rufián-Peña 
World J Gastroenterol 14(12):1949-1951. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1949
Paraneoplastic hyperinsulinism and secondary hypoglycaemia in a patient with advanced colon cancer: A rare association 
Roberto Díaz, Jorge Aparicio, Andrea Mendizábal, Marisa Faus, Tania Fleitas, Francisco Aparisi, Maria Martín 
World J Gastroenterol 14(12):1952-1954. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1952
Extraction and clipping repair of a chicken bone penetrating the gastric wall 
Jin-Soo Kim, Hyung-Keun Kim, Young-Seok Cho, Hiun-Suk Chae, Chang-Whan Kim, Byung-Wook Kim, Sok-Won Han, Kyu-Yong Choi 
World J Gastroenterol 14(12):1955-1957. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1955
Growth process of small pancreatic carcinoma: A case report with imaging observation for 22 months 
Takeshi Hisa, Hiroki Ohkubo, Satoshi Shiozawa, Hiroki Ishigame, Masato Takamatsu, Masayuki Furutake, Bunsei Nobukawa, Koichi Suda 
World J Gastroenterol 14(12):1958-1960. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1958
Peliosis and gummatous syphilis of the liver: A case report 
Jun-Fa Chen, Wei-Xia Chen, Hong-Ying Zhang, Wen-Yan Zhang 
World J Gastroenterol 14(12):1961-1963. Published online Mar 28, 2008. doi: 10.3748/wjg.14.1961