Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Mar 28, 2008; 14(12): 1805-1809
Published online Mar 28, 2008. doi: 10.3748/wjg.14.1805
Table 1 Description of the results of 6 studies in which intragastric injection of Botulinum Toxin type A was administered to obese patients for treatment of obesity
ReferencenDesignDose (UI)Follow-up (wk)Results
Garcia-Compean[23]12Pilot10012Reduction of body weight: No
antrumGastric emptying: Negative
Albani[24]8Pilot10016Reduction of body weight: No
Cardoso[25]12Pilot200/30012Early satiety: Yes
antrumReduction of body weight: No
Gastric emptying: Negative
Gui[26]14RCT1133/2008Early satiety: Yes
vs salineReduction of body weight: No
antrumGastric emptying: Negative
Foschi[27]24RCT1200 vs8Early satiety: Yes
salineReduction of weight: Yes
antrum + fundusGastric emptying: Positive
Max. gastric capacity for liquids: Positive
Mittermaier[28]10RCT200 vs24Early satiety: No
saline /antrumReduction of weight: No