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Open-Access Journal
Editorial
Diet and nutritional factors in inflammatory bowel diseases 
Danuta Owczarek, Tomasz Rodacki, Renata Domagała-Rodacka, Dorota Cibor, Tomasz Mach 
World J Gastroenterol 22(3):895-905. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.895
Frontier
Bisphosphonates as potential adjuvants for patients with cancers of the digestive system 
Celina Ang, Erin Doyle, Andrea Branch 
World J Gastroenterol 22(3):906-916. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.906
Topic Highlight
Inflammatory bowel disease imaging: Current practice and future directions 
Aoife Kilcoyne, Jess L Kaplan, Michael S Gee 
World J Gastroenterol 22(3):917-932. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.917
Protective links between vitamin D, inflammatory bowel disease and colon cancer 
Stacey Meeker, Audrey Seamons, Lillian Maggio-Price, Jisun Paik 
World J Gastroenterol 22(3):933-948. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.933
Application of computational methods in genetic study of inflammatory bowel disease 
Jin Li, Zhi Wei, Hakon Hakonarson 
World J Gastroenterol 22(3):949-960. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.949
Inflammatory bowel disease associated neoplasia: A surgeon’s perspective 
Azah A Althumairi, Mark G Lazarev, Susan L Gearhart 
World J Gastroenterol 22(3):961-973. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.961
Disrupted regulatory T cell homeostasis in inflammatory bowel diseases 
Christophe Pedros, Fanny Duguet, Abdelhadi Saoudi, Marianne Chabod 
World J Gastroenterol 22(3):974-995. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.974
Diagnostic imaging advances in murine models of colitis 
Markus Brückner, Philipp Lenz, Marcus M Mücke, Faekah Gohar, Peter Willeke, Dirk Domagk, Dominik Bettenworth 
World J Gastroenterol 22(3):996-1007. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.996
Assessment of stricturing Crohn's disease: Current clinical practice and future avenues 
Dominik Bettenworth, Tobias M Nowacki, Friederike Cordes, Boris Buerke, Frank Lenze 
World J Gastroenterol 22(3):1008-1016. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1008
How to predict clinical relapse in inflammatory bowel disease patients 
Elisa Liverani, Eleonora Scaioli, Richard John Digby, Matteo Bellanova, Andrea Belluzzi 
World J Gastroenterol 22(3):1017-1033. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1017
Protein tyrosine phosphatase non-receptor type 2 and inflammatory bowel disease 
Marianne R Spalinger, Declan F McCole, Gerhard Rogler, Michael Scharl 
World J Gastroenterol 22(3):1034-1044. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1034
Advances in nutritional therapy in inflammatory bowel diseases: Review 
Andrzej Wędrychowicz, Andrzej Zając, Przemysław Tomasik 
World J Gastroenterol 22(3):1045-1066. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1045
Endothelial dysfunction in inflammatory bowel diseases: Pathogenesis, assessment and implications 
Dorota Cibor, Renata Domagala-Rodacka, Tomasz Rodacki, Artur Jurczyszyn, Tomasz Mach, Danuta Owczarek 
World J Gastroenterol 22(3):1067-1077. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1067
Role of antibiotics for treatment of inflammatory bowel disease 
Orna Nitzan, Mazen Elias, Avi Peretz, Walid Saliba 
World J Gastroenterol 22(3):1078-1087. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1078
Influence of environmental factors on the onset and course of inflammatory bowel disease 
Amit Kumar Dutta, Ashok Chacko 
World J Gastroenterol 22(3):1088-1100. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1088
Quality of life: A critical outcome for all surgical treatments of gastric cancer 
Michael D McCall, Peter J Graham, Oliver F Bathe 
World J Gastroenterol 22(3):1101-1113. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1101
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer 
Ramakrishnan Ayloor Seshadri, Olivier Glehen 
World J Gastroenterol 22(3):1114-1130. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1114
Adjuvant radiochemotherapy for gastric cancer: Should we use prognostic factors to select patients? 
Linda Agolli, Riccardo Maurizi Enrici, Mattia Falchetto Osti 
World J Gastroenterol 22(3):1131-1138. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1131
Advanced gastric cancer: What we know and what we still have to learn 
Federico Coccolini, Giulia Montori, Marco Ceresoli, Simona Cima, Maria Carla Valli, Gabriela E Nita, Arianna Heyer, Fausto Catena, Luca Ansaloni 
World J Gastroenterol 22(3):1139-1159. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1139
Personalized medicine in gastric cancer: Where are we and where are we going? 
Alexandre A Jácome, Anelisa K Coutinho, Enaldo M Lima, Aline C Andrade, José Sebastião dos Santos 
World J Gastroenterol 22(3):1160-1171. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1160
Important considerations when contemplating endoscopic resection of undifferentiated-type early gastric cancer 
Jie-Hyun Kim 
World J Gastroenterol 22(3):1172-1178. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1172
Changing strategies for target therapy in gastric cancer 
Suk-young Lee, Sang Cheul Oh 
World J Gastroenterol 22(3):1179-1189. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1179
Genomic and epigenomic heterogeneity in molecular subtypes of gastric cancer 
Byungho Lim, Jong-Hwan Kim, Mirang Kim, Seon-Young Kim 
World J Gastroenterol 22(3):1190-1201. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1190
New blood markers detection technology: A leap in the diagnosis of gastric cancer 
Maneesh K Beeharry, Wen-Tao Liu, Min Yan, Zheng-Gang Zhu 
World J Gastroenterol 22(3):1202-1212. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1202
Emerging roles of non-coding RNAs in gastric cancer: Pathogenesis and clinical implications 
Shan-Shan Xie, Juan Jin, Xiao Xu, Wei Zhuo, Tian-Hua Zhou 
World J Gastroenterol 22(3):1213-1223. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1213
Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer 
Yang-Guang Shao, Ke Ning, Feng Li 
World J Gastroenterol 22(3):1224-1235. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1224
Review
Advanced gastrointestinal endoscopic imaging for inflammatory bowel diseases 
Gian Eugenio Tontini, Timo Rath, Helmut Neumann 
World J Gastroenterol 22(3):1246-1259. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1246
Pharmacokinetic drug interactions in liver disease: An update 
Pietro Palatini, Sara De Martin 
World J Gastroenterol 22(3):1260-1278. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1260
Emerging role of Hippo pathway in gastric and other gastrointestinal cancers 
Wei Kang, Alfred SL Cheng, Jun Yu, Ka Fai To 
World J Gastroenterol 22(3):1279-1288. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1279
Minireviews
Recent advances in photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid 
Noriaki Koizumi, Yoshinori Harada, Takeo Minamikawa, Hideo Tanaka, Eigo Otsuji, Tetsuro Takamatsu 
World J Gastroenterol 22(3):1289-1296. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1289
Endoscopic ultrasonography-guided biliary drainage: Who, when, which, and how? 
Kazuo Hara, Kenji Yamao, Nobumasa Mizuno, Susumu Hijioka, Hiroshi Imaoka, Masahiro Tajika, Tutomu Tanaka, Makoto Ishihara, Nozomi Okuno, Nobuhiro Hieda, Tukasa Yoshida, Yasumasa Niwa 
World J Gastroenterol 22(3):1297-1303. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1297
Antibody markers in the diagnosis of inflammatory bowel disease 
Keiichi Mitsuyama, Mikio Niwa, Hidetoshi Takedatsu, Hiroshi Yamasaki, Kotaro Kuwaki, Shinichiro Yoshioka, Ryosuke Yamauchi, Shuhei Fukunaga, Takuji Torimura 
World J Gastroenterol 22(3):1304-1310. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1304
Helicobacter pylori associated gastric intestinal metaplasia: Treatment and surveillance 
Kevin Sze-Hang Liu, Irene Oi-Ling Wong, Wai K Leung 
World J Gastroenterol 22(3):1311-1320. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1311
Systematic Reviews
Cytomegalovirus in inflammatory bowel disease: A systematic review 
Tessa EH Römkens, Geert J Bulte, Loes HC Nissen, Joost PH Drenth 
World J Gastroenterol 22(3):1321-1330. Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1321