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Topic Highlight
Colorectal cancer disparities: Issues, controversies and solutions 
Venkata S Tammana, Adeyinka O Laiyemo 
World J Gastroenterol 20(4):869-876. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.869
Evolving treatment strategies for colorectal cancer: A critical review of current therapeutic options 
Daniel C Damin, Anderson R Lazzaron 
World J Gastroenterol 20(4):877-887. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.877
Colorectal cancer biomarkers: To be or not to be? Cautionary tales from a road well travelled 
Kim YC Fung, Edouard Nice, Ilka Priebe, Damien Belobrajdic, Aloke Phatak, Leanne Purins, Bruce Tabor, Celine Pompeia, Trevor Lockett, Timothy E Adams, Antony Burgess, Leah Cosgrove 
World J Gastroenterol 20(4):888-898. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.888
How to select the optimal treatment for first line metastatic colorectal cancer 
Alexander Stein, Carsten Bokemeyer 
World J Gastroenterol 20(4):899-907. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.899
Inflammation and colorectal cancer, when microbiota-host mutualism breaks 
Marco Candela, Silvia Turroni, Elena Biagi, Franck Carbonero, Simone Rampelli, Carla Fiorentini, Patrizia Brigidi 
World J Gastroenterol 20(4):908-922. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.908
Cancer stem cells in colorectal cancer from pathogenesis to therapy: Controversies and perspectives 
Caterina Fanali, Donatella Lucchetti, Marisa Farina, Maddalena Corbi, Valerio Cufino, Achille Cittadini, Alessandro Sgambato 
World J Gastroenterol 20(4):923-942. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.923
Genetic and epigenetic biomarkers for diagnosis, prognosis and treatment of colorectal cancer 
Fabio Coppedè, Angela Lopomo, Roberto Spisni, Lucia Migliore 
World J Gastroenterol 20(4):943-956. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.943
Circulating and stool nucleic acid analysis for colorectal cancer diagnosis 
Giulia De Maio, Claudia Rengucci, Wainer Zoli, Daniele Calistri 
World J Gastroenterol 20(4):957-967. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.957
Cysteinyl leukotrienes and their receptors: Bridging inflammation and colorectal cancer 
Sayeh Savari, Katyayni Vinnakota, Yuan Zhang, Anita Sjölander 
World J Gastroenterol 20(4):968-977. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.968
Accumulation of aberrant DNA methylation during colorectal cancer development 
Eiji Sakai, Atsushi Nakajima, Atsushi Kaneda 
World J Gastroenterol 20(4):978-987. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.978
Radiofrequency ablation as treatment for pulmonary metastasis of colorectal cancer 
Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Susumu Kanazawa 
World J Gastroenterol 20(4):988-996. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.988
Overview of single-port laparoscopic surgery for colorectal cancers: Past, present, and the future 
Say-June Kim, Byung-Jo Choi, Sang Chul Lee 
World J Gastroenterol 20(4):997-1004. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.997
Review
Neuroanatomy of lower gastrointestinal pain disorders 
Wim Vermeulen, Joris G De Man, Paul A Pelckmans, Benedicte Y De Winter 
World J Gastroenterol 20(4):1005-1020. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1005
Original Article
Portal inflow preservation during portal diversion in small-for-size syndrome 
Xian-Qiang Wang, Yue-Fang Xu, Jing-Wang Tan, Wen-Ping Lv, Zhe Liu, Jian-Ping Zeng, Jia-Hong Dong 
World J Gastroenterol 20(4):1021-1029. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1021
Novel esophageal squamous cell carcinoma bone metastatic clone isolated by scintigraphy, X ray and micro PET/CT 
Bi-Zeng Zhao, Jie Cao, Jin-Chen Shao, Yan-Bing Sun, Li-Min Fan, Chun-Yu Wu, Sheng Liang, Bao-Feng Guo, Guang Yang, Wen-Hui Xie, Qing-Cheng Yang, Shun-Fang Yang 
World J Gastroenterol 20(4):1030-1037. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1030
Brief Article
Fecal immunochemical test accuracy in average-risk colorectal cancer screening 
Vicent Hernandez, Joaquin Cubiella, M Carmen Gonzalez-Mao, Felipe Iglesias, Concepción Rivera, M Begoña Iglesias, Lucía Cid, Ines Castro, Luisa de Castro, Pablo Vega, Jose Antonio Hermo, Ramiro Macenlle, Alfonso Martínez-Turnes, David Martínez-Ares, Pamela Estevez, Estela Cid, M Carmen Vidal, Angeles López-Martínez, Elisabeth Hijona, Marta Herreros-Villanueva, Luis Bujanda, Jose Ignacio Rodriguez-Prada; the COLONPREV study investigators 
World J Gastroenterol 20(4):1038-1047. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1038
Biopsy-driven diagnosis in infants with cholestatic jaundice in Iran 
Elham Talachian, Ali Bidari, Mitra Mehrazma, Nahid Nick-khah 
World J Gastroenterol 20(4):1048-1053. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1048
Intra-gastric triacetin alters upper gastrointestinal motility in conscious dogs 
Kazumasa Oosaka, Masaaki Tokuda, Naohiro Furukawa 
World J Gastroenterol 20(4):1054-1060. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1054
Long-term pretreatment with proton pump inhibitor and Helicobacter pylori eradication rates 
Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi 
World J Gastroenterol 20(4):1061-1066. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1061
Phase I study of postoperative radiotherapy combined with capecitabine for gastric cancer 
Xin Wang, Jing Jin, Ye-Xiong Li, Hua Ren, Hui Fang, Shu-Lian Wang, Yue-Ping Liu, Wei-Hu Wang, Zi-Hao Yu, Yong-Wen Song, Xin-Fan Liu 
World J Gastroenterol 20(4):1067-1073. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1067
Expression of granulocyte colony-stimulating factor receptor in rectal cancer 
Xiao-Dong Yang, Ping Huang, Feng Wang, Ze-Kuan Xu 
World J Gastroenterol 20(4):1074-1078. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1074
Role of hydrogen sulfide in portal hypertension and esophagogastric junction vascular disease 
Chao Wang, Juan Han, Liang Xiao, Chang-E Jin, Dong-Jian Li, Zhen Yang 
World J Gastroenterol 20(4):1079-1087. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1079
Diagnostic value of contrast enhanced ultrasound for splenic artery complications following acute pancreatitis 
Di-Ming Cai, Shyam Sundar Parajuly, Wen-Wu Ling, Yong-Zhong Li, Yan Luo 
World J Gastroenterol 20(4):1088-1094. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1088
Meta-Analysis
Combination of chemotherapy and immunotherapy for colon cancer in China: A meta-analysis 
Zheng-Xu Wang, Jun-Xia Cao, Zhi-Ping Liu, Yu-Xin Cui, Chun-Yun Li, Duo Li, Xiao-Yan Zhang, Jin-Long Liu, Jun-Li Li 
World J Gastroenterol 20(4):1095-1106. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1095
Meta-analysis of immunohistochemical expression of hypoxia inducible factor-1α as a prognostic role in gastric cancer 
Shuang Lin, Rui Ma, Xue-Yong Zheng, Hong Yu, Xiao Liang, Hui Lin, Xiu-Jun Cai 
World J Gastroenterol 20(4):1107-1113. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1107
Case Report
Family case of achalasia cardia: Case report and review of literature 
Yulia Viktorovna Evsyutina, Alexander Sergeevich Trukhmanov, Vladimir Trophimovich Ivashkin 
World J Gastroenterol 20(4):1114-1118. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1114
Endoscopic transgastric drainage of a gastric wall abscess after endoscopic submucosal dissection 
Osamu Dohi, Moyu Dohi, Ken Inoue, Yasuyuki Gen, Masayasu Jo, Kazuhiko Tokita 
World J Gastroenterol 20(4):1119-1122. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1119
Laparoscopic partial cystectomy with mucosal stripping of extraluminal duodenal duplication cysts 
Jeik Byun, Hyoung-Min Oh, Soo-Hong Kim, Hyun-Young Kim, Sung-Eun Jung, Kwi-Won Park, Woo-Sun Kim 
World J Gastroenterol 20(4):1123-1126. Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1123