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World J Gastroenterol. Jan 28, 2014; 20(4): 1074-1078
Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1074
Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1074
Expression of granulocyte colony-stimulating factor receptor in rectal cancer
Xiao-Dong Yang, Ping Huang, Feng Wang, Ze-Kuan Xu, Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
Author contributions: Yang XD and Huang P designed the research; Yang XD, Huang P and Xu ZK performed experiments and interpreted the data; Yang XD and Wang F wrote the paper.
Correspondence to: Ping Huang, MD, Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Road, Nanjing 210029, Jiangsu Province, China. huangpingdoctor@163.com
Telephone: +86-25-83718836 Fax: +86-25-83718836
Received: August 5, 2013
Revised: October 25, 2013
Accepted: November 12, 2013
Published online: January 28, 2014
Revised: October 25, 2013
Accepted: November 12, 2013
Published online: January 28, 2014
Core Tip
Core tip: It is unknown whether the expression of granulocyte colony-stimulating factor receptor (G-CSFR) can predict tumor response or sphincter preservation in patients with rectal cancer receiving preoperative radiotherapy. This study found that the expression of G-CSFR before preoperative irradiation may predict the radiosensitivity of rectal cancer.