BPG is committed to discovery and dissemination of knowledge
Open-Access Journal
Editorial
Hygiene hypothesis in inflammatory bowel disease: A critical review of the literature 
Natasha A Koloski, Laurel Bret, Graham Radford-Smith 
World J Gastroenterol 14(2):165-173. Published online Jan 14, 2008. doi: 10.3748/wjg.14.165
Observer
The spirit of Henry Norman Bethune and gastroenterology 
Hugh J Freeman 
World J Gastroenterol 14(2):174-175. Published online Jan 14, 2008. doi: 10.3748/wjg.14.174
Review
Overwhelming postsplenectomy infection syndrome in adults - A clinically preventable disease 
Takehiro Okabayashi, Kazuhiro Hanazaki 
World J Gastroenterol 14(2):176-179. Published online Jan 14, 2008. doi: 10.3748/wjg.14.176
Adenoviral gene therapy in gastric cancer: A review 
Nima Khalighinejad, Hesammodin Hariri, Omid Behnamfar, Arash Yousefi, Amir Momeni 
World J Gastroenterol 14(2):180-184. Published online Jan 14, 2008. doi: 10.3748/wjg.14.180
Topic Highlight
Non-alcoholic fatty liver disease and the metabolic syndrome: An update 
R Scott Rector, John P Thyfault, Yongzhong Wei, Jamal A Ibdah 
World J Gastroenterol 14(2):185-192. Published online Jan 14, 2008. doi: 10.3748/wjg.14.185
Nonalcoholic fatty liver disease and mitochondrial dysfunction 
Yongzhong Wei, R Scott Rector, John P Thyfault, Jamal A Ibdah 
World J Gastroenterol 14(2):193-199. Published online Jan 14, 2008. doi: 10.3748/wjg.14.193
Role of the JNK signal transduction pathway in inflammatory bowel disease 
Praveen K Roy, Farzana Rashid, Jack Bragg, Jamal A Ibdah 
World J Gastroenterol 14(2):200-202. Published online Jan 14, 2008. doi: 10.3748/wjg.14.200
Esophageal Cancer
Methylation of TIMP3 in esophageal squamous cell carcinoma 
Eric Smith, Neville J De Young, Zi-Qiang Tian, Maria Caruso, Andrew R Ruszkiewicz, Jun-Feng Liu, Glyn G Jamieson, Paul A Drew 
World J Gastroenterol 14(2):203-210. Published online Jan 14, 2008. doi: 10.3748/wjg.14.203
Colorectal Cancer
Clinical significance of type VI pit pattern subclassification in determining the depth of invasion of colorectal neoplasms 
Hiroyuki Kanao, Shinji Tanaka, Shiro Oka, Iwao Kaneko, Shigeto Yoshida, Koji Arihiro, Masaharu Yoshihara, Kazuaki Chayama 
World J Gastroenterol 14(2):211-217. Published online Jan 14, 2008. doi: 10.3748/wjg.14.211
Basic Research
Hepatic stellate cells may be potential effectors of platelet activating factor induced portal hypertension 
Yan Chen, Chun-Ping Wang, Yin-Ying Lu, Lin Zhou, Shu-Hui Su, Hong-Jun Jia, Yong-Yi Feng, Yong-Ping Yang 
World J Gastroenterol 14(2):218-223. Published online Jan 14, 2008. doi: 10.3748/wjg.14.218
Expression of thymidine kinase mediated by a novel non-viral delivery system under the control of vascular endothelial growth factor receptor 2 promoter selectively kills human umbilical vein endothelial cells 
Ying Wang, Hui-Xiong Xu, Ming-De Lu, Qing Tang 
World J Gastroenterol 14(2):224-230. Published online Jan 14, 2008. doi: 10.3748/wjg.14.224
Clinical Research
Clear cell colitis: A form of microscopic colitis in children 
Jan Józefczuk, Bogdan Marian Wozniewicz 
World J Gastroenterol 14(2):231-235. Published online Jan 14, 2008. doi: 10.3748/wjg.14.231
Rapid Communication
Elevated nitric oxide and 3’,5’ cyclic guanosine monophosphate levels in patients with alcoholic cirrhosis 
Cíntia Siqueira, Miguel Carneiro de Moura, Ana Julia Pedro, Paula Rocha 
World J Gastroenterol 14(2):236-242. Published online Jan 14, 2008. doi: 10.3748/wjg.14.236
Promoter polymorphism of transforming growth factor-β1 gene and ulcerative colitis 
B Tamizifar, KB Lankarani, S Naeimi, M Rismankar Zadeh, A Taghavi, A Ghaderi 
World J Gastroenterol 14(2):243-247. Published online Jan 14, 2008. doi: 10.3748/wjg.14.243
Prevalence and dietetic management of mild gastrointestinal disorders in milk-fed infants 
D Infante Pina, X Badia Llach, B Ariño-Armengol, V Villegas Iglesias 
World J Gastroenterol 14(2):248-254. Published online Jan 14, 2008. doi: 10.3748/wjg.14.248
Efficacy and safety of pegylated-interferon α-2a in hemodialysis patients with chronic hepatitis C 
Celal Ayaz, Mustafa Kemal Celen, Ugur Nedim Yuce, Mehmet Faruk Geyik 
World J Gastroenterol 14(2):255-259. Published online Jan 14, 2008. doi: 10.3748/wjg.14.255
Role of echo Doppler ultrasonography in the evaluation of postprandial hyperemia in cirrhotic patients 
Osman Ozdogan, Huseyin Atalay, Cagatay Cimsit, Veysel Tahan, Sena Tokay, Adnan Giral, Nese Imeryuz, Feyyaz Baltacioglu, Davut Tuney, Canan Erzen, Nurdan Tozun 
World J Gastroenterol 14(2):260-264. Published online Jan 14, 2008. doi: 10.3748/wjg.14.260
Is obesity associated with gastropharyngeal reflux disease? 
Cheol Woong Choi, Gwang Ha Kim, Chul Soo Song, Soo Geun Wang, Byung Joo Lee, Hoseok I, Dae Hwan Kang, Geun Am Song 
World J Gastroenterol 14(2):265-271. Published online Jan 14, 2008. doi: 10.3748/wjg.14.265
Referral for anorectal function evaluation is indicated in 65% and beneficial in 92% of patients 
Maria M Szojda, Erik Tanis, Chris JJ Mulder, Richelle JF Felt-Bersma 
World J Gastroenterol 14(2):272-277. Published online Jan 14, 2008. doi: 10.3748/wjg.14.272
Changing spectrum of Budd-Chiari syndrome in India with special reference to non-surgical treatment 
Deepak N Amarapurkar, Sundeep J Punamiya, Nikhil D Patel 
World J Gastroenterol 14(2):278-285. Published online Jan 14, 2008. doi: 10.3748/wjg.14.278
Child-Pugh-Turcott versus Meld score for predicting survival in a retrospective cohort of black African cirrhotic patients 
KA Attia, KC Ackoundou-N’guessan, AT N’dri-yoman, AK Mahassadi, E Messou, YF Bathaix, YH Kissi 
World J Gastroenterol 14(2):286-291. Published online Jan 14, 2008. doi: 10.3748/wjg.14.286
Expression of pituitary homeobox 1 gene in human gastric carcinogenesis and its clinicopathological significance 
Ya-Nan Chen, Hong Chen, Yan Xu, Xue Zhang, Yang Luo 
World J Gastroenterol 14(2):292-297. Published online Jan 14, 2008. doi: 10.3748/wjg.14.292
Detection of hMSH2 and hMLH1 mutations in Chinese hereditary non-polyposis colorectal cancer kindreds 
Chang-Hua Zhang, Yu-Long He, Fang-Jin Wang, Wu Song, Xi-Yu Yuan, Dong-Jie Yang, Chuang-Qi Chen, Shi-Rong Cai, Wen-Hua Zhan 
World J Gastroenterol 14(2):298-302. Published online Jan 14, 2008. doi: 10.3748/wjg.14.298
Assessment of duodenal circular drainage in treatment of superior mesenteric artery syndrome 
Wei-Liang Yang, Xin-Chen Zhang 
World J Gastroenterol 14(2):303-306. Published online Jan 14, 2008. doi: 10.3748/wjg.14.303
Association between the presence of H pylori in the liver and hepatocellular carcinoma: A meta-analysis 
Shi-Ying Xuan, Yong-Ning Xin, An-Jin Chen, Quan-Jiang Dong, Xin Qiang, Ning Li, Ming-Hua Zheng, Hua-Shi Guan 
World J Gastroenterol 14(2):307-312. Published online Jan 14, 2008. doi: 10.3748/wjg.14.307
Small intestinal bacteria overgrowth decreases small intestinal motility in the NASH rats 
Wan-Chun Wu, Wei Zhao, Sheng Li 
World J Gastroenterol 14(2):313-317. Published online Jan 14, 2008. doi: 10.3748/wjg.14.313
Case Report
Acute inflammatory demyelinating polyneuropathy associated with pegylated interferon α 2a therapy for chronic hepatitis C virus infection 
Vijay Khiani, Thomas Kelly, Adeel Shibli, Donald Jensen, Smruti R Mohanty 
World J Gastroenterol 14(2):318-321. Published online Jan 14, 2008. doi: 10.3748/wjg.14.318
Letters To The Editor
Clinical guidelines: Involvement of peers increases physician adherence 
Pascal Vignally, Jean Charles Grimaud, Roland Sambuc, Stéphanie Gentile 
World J Gastroenterol 14(2):322-323. Published online Jan 14, 2008. doi: 10.3748/wjg.14.322