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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
1
Endoscopic ear surgery: A case series and first United Kingdom experience  
Hala Kanona, Jagdeep Singh Virk, Anthony Owa 
World J Clin Cases 3(3):310-317. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.310
2
Treatment of Helicobacter pylori infection: Current and future insights  
Maliheh Safavi, Reyhaneh Sabourian, Alireza Foroumadi 
World J Clin Cases 4(1):5-19. Published online Jan 16, 2016. doi: 10.12998/wjcc.v4.i1.5
3
Clinical variants of pityriasis rosea  
Francisco Urbina, Anupam Das, Emilio Sudy 
World J Clin Cases 5(6):203-211. Published online Jun 16, 2017. doi: 10.12998/wjcc.v5.i6.203
4
Gingival enlargements: Differential diagnosis and review of literature  
Amit Arvind Agrawal 
World J Clin Cases 3(9):779-788. Published online Sep 16, 2015. doi: 10.12998/wjcc.v3.i9.779
5
Clinical and radiographic features of Hutchinson-Gilford progeria syndrome: A case report  
Daniel Berretta Alves, Juliana Melo Silva, Tatiany Oliveira Menezes, Rosely Santos Cavaleiro, Fabrício Mesquita Tuji, Marcio Ajudarte Lopes, Alexandre Augusto Zaia, Ricardo Della Coletta 
World J Clin Cases 2(3):67-71. Published online Mar 16, 2014. doi: 10.12998/wjcc.v2.i3.67
6
7
Deadly case of Pasteurella multocida aortitis and mycotic aneurysm following a cat bite  
Dennis Dane Cho, Yaniv Berliner, David Carr 
World J Clin Cases 4(6):142-145. Published online Jun 16, 2016. doi: 10.12998/wjcc.v4.i6.142
8
Low expression of angiotensinogen and dipeptidyl peptidase 1 in saliva of patients with proliferative verrucous leukoplakia  
Isadora Luana Flores, Alan Roger Santos-Silva, Ricardo Della Coletta, Adriana Franco Paes Leme, Marcio Ajudarte Lopes 
World J Clin Cases 4(11):356-363. Published online Nov 16, 2016. doi: 10.12998/wjcc.v4.i11.356
9
Treatment of sepsis: What is the antibiotic choice in bacteremia due to carbapenem resistant Enterobacteriaceae?  
Fatema Alhashem, Nicolette Leonie Tiren-Verbeet, Emine Alp, Mehmet Doganay 
World J Clin Cases 5(8):324-332. Published online Aug 16, 2017. doi: 10.12998/wjcc.v5.i8.324
10
New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers  
Armel Hervé Nwabo Kamdje, Paul Faustin Seke Etet, Lorella Vecchio, Richard Simo Tagne, Jeremie Mbo Amvene, Jean-Marc Muller, Mauro Krampera, Kiven Erique Lukong 
World J Clin Cases 2(12):769-786. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.769
11
Cervical cancer screening: A never-ending developing program  
Ciro Comparetto, Franco Borruto 
World J Clin Cases 3(7):614-624. Published online Jul 16, 2015. doi: 10.12998/wjcc.v3.i7.614
12
Tick-borne encephalitis: A review of epidemiology, clinical characteristics, and management  
Petra Bogovic, Franc Strle 
World J Clin Cases 3(5):430-441. Published online May 16, 2015. doi: 10.12998/wjcc.v3.i5.430
13
From variome to phenome: Pathogenesis, diagnosis and management of ectopic mineralization disorders  
Eva YG De Vilder, Olivier M Vanakker 
World J Clin Cases 3(7):556-574. Published online Jul 16, 2015. doi: 10.12998/wjcc.v3.i7.556
14
Long-term stabilization of stage 4 colon cancer using sodium dichloroacetate therapy  
Akbar Khan, Douglas Andrews, Anneke C Blackburn 
World J Clin Cases 4(10):336-343. Published online Oct 16, 2016. doi: 10.12998/wjcc.v4.i10.336
15
Drug-targeting methodologies with applications: A review  
Clement Kleinstreuer, Yu Feng, Emily Childress 
World J Clin Cases 2(12):742-756. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.742
16
Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside  
Ming-Feng Lin, Chung-Yu Lan 
World J Clin Cases 2(12):787-814. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.787
17
Gall bladder carcinoma: Aggressive malignancy with protean loco-regional and distant spread  
Amit Nandan Dhar Dwivedi, Shivi Jain, Ruhi Dixit 
World J Clin Cases 3(3):231-244. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.231
18
Cytopathologic diagnosis of fine needle aspiration biopsies of thyroid nodules  
Evangelos P Misiakos, Niki Margari, Christos Meristoudis, Nickolas Machairas, Dimitrios Schizas, Konstantinos Petropoulos, Aris Spathis, Petros Karakitsos, Anastasios Machairas 
World J Clin Cases 4(2):38-48. Published online Feb 16, 2016. doi: 10.12998/wjcc.v4.i2.38
19
Highlights in pathogenesis of vitiligo  
Ghada F Mohammed, Amal HA Gomaa, Mohammed Saleh Al-Dhubaibi 
World J Clin Cases 3(3):221-230. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.221
20
Combined surgical-orthodontic rehabilitation of cleidocranial dysplasia: 5 years follow-up  
Emre Çimen, Ömür Dereci, Ayşegül Mine Tüzüner-Öncül, Duygu Yazıcıoğlu, Erhan Özdiler, Aslı Şenol, Nejat Bora Sayan 
World J Clin Cases 3(8):751-756. Published online Aug 16, 2015. doi: 10.12998/wjcc.v3.i8.751
21
Clinical and diagnostic aspects of gluten related disorders  
Francesco Tovoli, Chiara Masi, Elena Guidetti, Giulia Negrini, Paola Paterini, Luigi Bolondi 
World J Clin Cases 3(3):275-284. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.275
22
Enamel microabrasion: An overview of clinical and scientific considerations  
Núbia Inocencya Pavesi Pini, Daniel Sundfeld-Neto, Flavio Henrique Baggio Aguiar, Renato Herman Sundfeld, Luis Roberto Marcondes Martins, José Roberto Lovadino, Débora Alves Nunes Leite Lima 
World J Clin Cases 3(1):34-41. Published online Jan 16, 2015. doi: 10.12998/wjcc.v3.i1.34
23
Recent advances in the HER2 targeted therapy of gastric cancer  
Tasuku Matsuoka, Masakazu Yashiro 
World J Clin Cases 3(1):42-51. Published online Jan 16, 2015. doi: 10.12998/wjcc.v3.i1.42
24
Precancerous lesions of oral mucosa  
Gurkan Yardimci, Zekayi Kutlubay, Burhan Engin, Yalcin Tuzun 
World J Clin Cases 2(12):866-872. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.866
25
Evolution, current status and advances in application of platelet concentrate in periodontics and implantology  
Amit Arvind Agrawal 
World J Clin Cases 5(5):159-171. Published online May 16, 2017. doi: 10.12998/wjcc.v5.i5.159
26
Giant cell arteritis: Current treatment and management  
Cristina Ponte, Ana Filipa Rodrigues, Lorraine O’Neill, Raashid Ahmed Luqmani 
World J Clin Cases 3(6):484-494. Published online Jun 16, 2015. doi: 10.12998/wjcc.v3.i6.484
27
28
Posterior partially edentulous jaws, planning a rehabilitation with dental implants  
Douglas R Monteiro, Emily V F Silva, Eduardo P Pellizzer, Osvaldo Magro Filho, Marcelo C Goiato 
World J Clin Cases 3(1):65-76. Published online Jan 16, 2015. doi: 10.12998/wjcc.v3.i1.65
29
Epilepsy associated tumors: Review article  
Marco Giulioni, Gianluca Marucci, Matteo Martinoni, Anna Federica Marliani, Francesco Toni, Fiorina Bartiromo, Lilia Volpi, Patrizia Riguzzi, Francesca Bisulli, Ilaria Naldi, Roberto Michelucci, Agostino Baruzzi, Paolo Tinuper, Guido Rubboli 
World J Clin Cases 2(11):623-641. Published online Nov 16, 2014. doi: 10.12998/wjcc.v2.i11.623
30
Review and update on the molecular basis of Leber congenital amaurosis  
Oscar Francisco Chacon-Camacho, Juan Carlos Zenteno 
World J Clin Cases 3(2):112-124. Published online Feb 16, 2015. doi: 10.12998/wjcc.v3.i2.112
31
Multidetector computed tomography of temporomandibular joint: A road less travelled  
Shivani Pahwa, Ashu Seith Bhalla, Ajoy Roychaudhary, Ongkila Bhutia 
World J Clin Cases 3(5):442-449. Published online May 16, 2015. doi: 10.12998/wjcc.v3.i5.442
32
Fluoroscopy guided percutaneous renal access in prone position  
Gyanendra R Sharma, Pankaj N Maheshwari, Anshu G Sharma, Reeta P Maheshwari, Ritwik S Heda, Sakshi P Maheshwari 
World J Clin Cases 3(3):245-264. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.245
33
Multilevel oblique corpectomies as an effective surgical option to treat cervical chordoma in a young girl  
Roberto Delfini, Daniele Marruzzo, Roberto Tarantino, Nicola Marotta, Alessandro Landi 
World J Clin Cases 2(3):57-61. Published online Mar 16, 2014. doi: 10.12998/wjcc.v2.i3.57
34
Adenoid cystic carcinoma of breast: Recent advances  
Kosuke Miyai, Mary R Schwartz, Mukul K Divatia, Rose C Anton, Yong Wook Park, Alberto G Ayala, Jae Y Ro 
World J Clin Cases 2(12):732-741. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.732
35
Targeting chronic lymphocytic leukemia cells in the tumor microenviroment: A review of the in vitro and clinical trials to date  
Kyle Crassini, Stephen P Mulligan, O Giles Best 
World J Clin Cases 3(8):694-704. Published online Aug 16, 2015. doi: 10.12998/wjcc.v3.i8.694
36
Coumadin ridge: An incidental finding of a left atrial pseudotumor on transthoracic echocardiography  
Aadil Mubeen Lodhi, Tin Nguyen, Christopher Bianco, Assad Movahed 
World J Clin Cases 3(9):831-834. Published online Sep 16, 2015. doi: 10.12998/wjcc.v3.i9.831
37
Facial nerve paralysis in children  
Andrea Ciorba, Virginia Corazzi, Veronica Conz, Chiara Bianchini, Claudia Aimoni 
World J Clin Cases 3(12):973-979. Published online Dec 16, 2015. doi: 10.12998/wjcc.v3.i12.973
38
39
Renal cell carcinoma: Evolving and emerging subtypes  
Suzanne M Crumley, Mukul Divatia, Luan Truong, Steven Shen, Alberto G Ayala, Jae Y Ro 
World J Clin Cases 1(9):262-275. Published online Dec 16, 2013. doi: 10.12998/wjcc.v1.i9.262
40
Spinal pedicle subtraction osteotomy for fixed sagittal imbalance patients  
Seung-Jae Hyun, Yongjung J Kim, Seung-Chul Rhim 
World J Clin Cases 1(8):242-248. Published online Nov 16, 2013. doi: 10.12998/wjcc.v1.i8.242
41
Implant biomaterials: A comprehensive review  
Monika Saini, Yashpal Singh, Pooja Arora, Vipin Arora, Krati Jain 
World J Clin Cases 3(1):52-57. Published online Jan 16, 2015. doi: 10.12998/wjcc.v3.i1.52
42
Successful recanalization with multimodality endovascular interventional therapy in acute ischemic stroke  
Amorn Jongsathapongpan, Anuchit Raumthanthong, Sombat Muengtaweepongsa 
World J Clin Cases 2(3):78-85. Published online Mar 16, 2014. doi: 10.12998/wjcc.v2.i3.78
43
Robotic single-site supracervical hysterectomy with manual morcellation: Preliminary experience  
Dah-Ching Ding, Mun-Kun Hong, Tang-Yuan Chu, Yu-Hsun Chang, Hwan-Wun Liu 
World J Clin Cases 5(5):172-177. Published online May 16, 2017. doi: 10.12998/wjcc.v5.i5.172
44
Promising new treatment targets in patients with fibrosing lung disorders  
Martina Sterclova, Martina Vasakova 
World J Clin Cases 2(11):668-675. Published online Nov 16, 2014. doi: 10.12998/wjcc.v2.i11.668
45
Diabetes mellitus and electrolyte disorders  
George Liamis, Evangelos Liberopoulos, Fotios Barkas, Moses Elisaf 
World J Clin Cases 2(10):488-496. Published online Oct 16, 2014. doi: 10.12998/wjcc.v2.i10.488
46
Breath-based meditation: A mechanism to restore the physiological and cognitive reserves for optimal human performance  
Kirtigandha Salwe Carter, Robert Carter III 
World J Clin Cases 4(4):99-102. Published online Apr 16, 2016. doi: 10.12998/wjcc.v4.i4.99
47
State-of-the-Art management of knee osteoarthritis  
Kenton H Fibel, Howard J Hillstrom, Brian C Halpern 
World J Clin Cases 3(2):89-101. Published online Feb 16, 2015. doi: 10.12998/wjcc.v3.i2.89
48
Horseshoe thrombus in a patient with mechanical prosthetic mitral valve: A case report and review of literature  
Sanjay Mehra, Assad Movahed, Carlos Espinoza, Constantin B Marcu 
World J Clin Cases 3(9):838-842. Published online Sep 16, 2015. doi: 10.12998/wjcc.v3.i9.838
49
Focal epithelial hyperplasia in a human immuno-deficiency virus patient treated with laser surgery  
Alexandros Galanakis, Gaspare Palaia, Gianluca Tenore, Alessandro Del Vecchio, Umberto Romeo 
World J Clin Cases 2(7):293-296. Published online Jul 16, 2014. doi: 10.12998/wjcc.v2.i7.293
50
Pathways of fear and anxiety in dentistry: A review  
Ava Elizabeth Carter, Geoff Carter, Mark Boschen, Emad AlShwaimi, Roy George 
World J Clin Cases 2(11):642-653. Published online Nov 16, 2014. doi: 10.12998/wjcc.v2.i11.642