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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
Clinical variants of pityriasis rosea  
Francisco Urbina, Anupam Das, Emilio Sudy 
World J Clin Cases 5(6):203-211. Published online Jun 16, 2017. doi: 10.12998/wjcc.v5.i6.203
Gangrenous cholecystitis: A silent but potential fatal disease in patients with diabetic neuropathy. A case report  
Melorin Mehrzad, Charles C Jehle, Lauren O Roussel, Raman Mehrzad 
World J Clin Cases 6(15):1007-1011. Published online Dec 6, 2018. doi: 10.12998/wjcc.v6.i15.1007
Update on global epidemiology of viral hepatitis and preventive strategies  
Meryem Jefferies, Bisma Rauff, Harunor Rashid, Thao Lam, Shafquat Rafiq 
World J Clin Cases 6(13):589-599. Published online Nov 6, 2018. doi: 10.12998/wjcc.v6.i13.589
Treatment of Helicobacter pylori infection: Current and future insights  
Maliheh Safavi, Reyhaneh Sabourian, Alireza Foroumadi 
World J Clin Cases 4(1):5-19. Published online Jan 16, 2016. doi: 10.12998/wjcc.v4.i1.5
Postpartum pubic symphysis diastasis-conservative and surgical treatment methods, incidence of complications: Two case reports and a review of the literature  
Kristina Norvilaite, Monika Kezeviciute, Diana Ramasauskaite, Audrone Arlauskiene, Daiva Bartkeviciene, Valentinas Uvarovas 
World J Clin Cases 8(1):110-119. Published online Jan 6, 2020. doi: 10.12998/wjcc.v8.i1.110
Stability and infectivity of coronaviruses in inanimate environments  
Shi-Yan Ren, Wen-Biao Wang, Ya-Guang Hao, Hao-Ran Zhang, Zhi-Chao Wang, Ye-Lin Chen, Rong-Ding Gao 
World J Clin Cases 8(8):1391-1399. Published online Apr 26, 2020. doi: 10.12998/wjcc.v8.i8.1391
Endoscopic ear surgery: A case series and first United Kingdom experience  
Hala Kanona, Jagdeep Singh Virk, Anthony Owa 
World J Clin Cases 3(3):310-317. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.310
Fear can be more harmful than the severe acute respiratory syndrome coronavirus 2 in controlling the corona virus disease 2019 epidemic  
Shi-Yan Ren, Rong-Ding Gao, Ye-Lin Chen 
World J Clin Cases 8(4):652-657. Published online Feb 26, 2020. doi: 10.12998/wjcc.v8.i4.652
High serum lactate dehydrogenase and dyspnea: Positive predictors of adverse outcome in critical COVID-19 patients in Yichang  
Xiao-Ting Lv, Yong-Ping Zhu, Ai-Guo Cheng, Yong-Xu Jin, Hai-Bo Ding, Cai-Yun Wang, Shu-Yu Zhang, Gong-Ping Chen, Qing-Quan Chen, Qi-Cai Liu 
World J Clin Cases 8(22):5535-5546. Published online Nov 26, 2020. doi: 10.12998/wjcc.v8.i22.5535
Implant biomaterials: A comprehensive review  
Monika Saini, Yashpal Singh, Pooja Arora, Vipin Arora, Krati Jain 
World J Clin Cases 3(1):52-57. Published online Jan 16, 2015. doi: 10.12998/wjcc.v3.i1.52
Long-term stabilization of stage 4 colon cancer using sodium dichloroacetate therapy  
Akbar Khan, Douglas Andrews, Anneke C Blackburn 
World J Clin Cases 4(10):336-343. Published online Oct 16, 2016. doi: 10.12998/wjcc.v4.i10.336
Tick-borne encephalitis: A review of epidemiology, clinical characteristics, and management  
Petra Bogovic, Franc Strle 
World J Clin Cases 3(5):430-441. Published online May 16, 2015. doi: 10.12998/wjcc.v3.i5.430
Evaluation and management of acute pancreatitis  
Ahmed T Chatila, Mohammad Bilal, Praveen Guturu 
World J Clin Cases 7(9):1006-1020. Published online May 6, 2019. doi: 10.12998/wjcc.v7.i9.1006
Treatment of sepsis: What is the antibiotic choice in bacteremia due to carbapenem resistant Enterobacteriaceae?  
Fatema Alhashem, Nicolette Leonie Tiren-Verbeet, Emine Alp, Mehmet Doganay 
World J Clin Cases 5(8):324-332. Published online Aug 16, 2017. doi: 10.12998/wjcc.v5.i8.324
Immune checkpoint inhibitor-induced colitis: A comprehensive review  
Aniruddh Som, Rohan Mandaliya, Dana Alsaadi, Maham Farshidpour, Aline Charabaty, Nidhi Malhotra, Mark C Mattar 
World J Clin Cases 7(4):405-418. Published online Feb 26, 2019. doi: 10.12998/wjcc.v7.i4.405
Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside  
Ming-Feng Lin, Chung-Yu Lan 
World J Clin Cases 2(12):787-814. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.787
Unexplained elevation of erythrocyte sedimentation rate in a patient recovering from COVID-19: A case report  
Sheng-Lan Pu, Xiang-Yan Zhang, Dai-Shun Liu, Ba-Ning Ye, Jian-Quan Li 
World J Clin Cases 9(6):1394-1401. Published online Feb 26, 2021. doi: 10.12998/wjcc.v9.i6.1394
Clinical and diagnostic aspects of gluten related disorders  
Francesco Tovoli, Chiara Masi, Elena Guidetti, Giulia Negrini, Paola Paterini, Luigi Bolondi 
World J Clin Cases 3(3):275-284. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.275
Helicobacter pylori may be an initiating factor in newly diagnosed ulcerative colitis patients: A pilot study  
Loai Mansour, Ferial El-Kalla, Abdelrahman Kobtan, Sherief Abd-Elsalam, Mohamed Yousef, Samah Soliman, Lobna Abo Ali, Walaa Elkhalawany, Ibrahim Amer, Heba Harras, Maha M Hagras, Mohamed Elhendawy 
World J Clin Cases 6(13):641-649. Published online Nov 6, 2018. doi: 10.12998/wjcc.v6.i13.641
Deadly case of Pasteurella multocida aortitis and mycotic aneurysm following a cat bite  
Dennis Dane Cho, Yaniv Berliner, David Carr 
World J Clin Cases 4(6):142-145. Published online Jun 16, 2016. doi: 10.12998/wjcc.v4.i6.142
Intracranial pressure monitoring: Gold standard and recent innovations  
Deb Sanjay Nag, Seelora Sahu, Amlan Swain, Shashi Kant 
World J Clin Cases 7(13):1535-1553. Published online Jul 6, 2019. doi: 10.12998/wjcc.v7.i13.1535
Cytopathologic diagnosis of fine needle aspiration biopsies of thyroid nodules  
Evangelos P Misiakos, Niki Margari, Christos Meristoudis, Nickolas Machairas, Dimitrios Schizas, Konstantinos Petropoulos, Aris Spathis, Petros Karakitsos, Anastasios Machairas 
World J Clin Cases 4(2):38-48. Published online Feb 16, 2016. doi: 10.12998/wjcc.v4.i2.38
Diabetes mellitus and electrolyte disorders  
George Liamis, Evangelos Liberopoulos, Fotios Barkas, Moses Elisaf 
World J Clin Cases 2(10):488-496. Published online Oct 16, 2014. doi: 10.12998/wjcc.v2.i10.488
From variome to phenome: Pathogenesis, diagnosis and management of ectopic mineralization disorders  
Eva YG De Vilder, Olivier M Vanakker 
World J Clin Cases 3(7):556-574. Published online Jul 16, 2015. doi: 10.12998/wjcc.v3.i7.556
Nutrition management in acute pancreatitis: Clinical practice consideration  
Narisorn Lakananurak, Leah Gramlich 
World J Clin Cases 8(9):1561-1573. Published online May 6, 2020. doi: 10.12998/wjcc.v8.i9.1561
Low expression of angiotensinogen and dipeptidyl peptidase 1 in saliva of patients with proliferative verrucous leukoplakia  
Isadora Luana Flores, Alan Roger Santos-Silva, Ricardo Della Coletta, Adriana Franco Paes Leme, Marcio Ajudarte Lopes 
World J Clin Cases 4(11):356-363. Published online Nov 16, 2016. doi: 10.12998/wjcc.v4.i11.356
Enamel microabrasion: An overview of clinical and scientific considerations  
Núbia Inocencya Pavesi Pini, Daniel Sundfeld-Neto, Flavio Henrique Baggio Aguiar, Renato Herman Sundfeld, Luis Roberto Marcondes Martins, José Roberto Lovadino, Débora Alves Nunes Leite Lima 
World J Clin Cases 3(1):34-41. Published online Jan 16, 2015. doi: 10.12998/wjcc.v3.i1.34
Giant cell arteritis: Current treatment and management  
Cristina Ponte, Ana Filipa Rodrigues, Lorraine O’Neill, Raashid Ahmed Luqmani 
World J Clin Cases 3(6):484-494. Published online Jun 16, 2015. doi: 10.12998/wjcc.v3.i6.484
Clinical and radiographic features of Hutchinson-Gilford progeria syndrome: A case report  
Daniel Berretta Alves, Juliana Melo Silva, Tatiany Oliveira Menezes, Rosely Santos Cavaleiro, Fabrício Mesquita Tuji, Marcio Ajudarte Lopes, Alexandre Augusto Zaia, Ricardo Della Coletta 
World J Clin Cases 2(3):67-71. Published online Mar 16, 2014. doi: 10.12998/wjcc.v2.i3.67
New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers  
Armel Hervé Nwabo Kamdje, Paul Faustin Seke Etet, Lorella Vecchio, Richard Simo Tagne, Jeremie Mbo Amvene, Jean-Marc Muller, Mauro Krampera, Kiven Erique Lukong 
World J Clin Cases 2(12):769-786. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.769
Evolution, current status and advances in application of platelet concentrate in periodontics and implantology  
Amit Arvind Agrawal 
World J Clin Cases 5(5):159-171. Published online May 16, 2017. doi: 10.12998/wjcc.v5.i5.159
Cervical cancer screening: A never-ending developing program  
Ciro Comparetto, Franco Borruto 
World J Clin Cases 3(7):614-624. Published online Jul 16, 2015. doi: 10.12998/wjcc.v3.i7.614
Gall bladder carcinoma: Aggressive malignancy with protean loco-regional and distant spread  
Amit Nandan Dhar Dwivedi, Shivi Jain, Ruhi Dixit 
World J Clin Cases 3(3):231-244. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.231
Atypical presentation of SARS-CoV-2 infection: A case report  
Rui-Lin Li, Shu-Guang Chu, Yu Luo, Zhen-Hao Huang, Ying Hao, Cheng-Hui Fan 
World J Clin Cases 8(7):1265-1270. Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1265
Highlights in pathogenesis of vitiligo  
Ghada F Mohammed, Amal HA Gomaa, Mohammed Saleh Al-Dhubaibi 
World J Clin Cases 3(3):221-230. Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.221
Drug-targeting methodologies with applications: A review  
Clement Kleinstreuer, Yu Feng, Emily Childress 
World J Clin Cases 2(12):742-756. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.742
Precancerous lesions of oral mucosa  
Gurkan Yardimci, Zekayi Kutlubay, Burhan Engin, Yalcin Tuzun 
World J Clin Cases 2(12):866-872. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.866
Extranodal natural killer/T-cell lymphoma (nasal type) presenting as a perianal abscess: A case report  
Yan-Ni Liu, Yong Zhu, Jia-Jun Tan, Guang-Shu Shen, Shu-Liang Huang, Chun-Gen Zhou, Shao-Hua Huangfu, Rui Zhang, Xiao-Bo Huang, Ling Wang, Qi Zhang, Bin Jiang 
World J Clin Cases 7(8):992-1000. Published online Apr 26, 2019. doi: 10.12998/wjcc.v7.i8.992
Hair regrowth following fecal microbiota transplantation in an elderly patient with alopecia areata: A case report and review of the literature  
Wen-Rui Xie, Xiao-Ya Yang, Harry Hua-Xiang Xia, Li-Hao Wu, Xing-Xiang He 
World J Clin Cases 7(19):3074-3081. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3074
Endodontic management of the maxillary first molars with two root canals: A case report and review of the literature  
Jie Liu, Ke-Hua Que, Zuo-Hui Xiao, Wen Wen 
World J Clin Cases 7(1):79-88. Published online Jan 6, 2019. doi: 10.12998/wjcc.v7.i1.79
Comparison of the clinical efficacy of two different types of post systems which were restored with composite restorations  
Buket Ayna, Emrah Ayna, Sema Çelenk, Emine Göncü Başaran, Berivan Dündar Yılmaz, İbrahim Halil Tacir, Mehmet Cudi Tuncer 
World J Clin Cases 6(3):27-34. Published online Mar 16, 2018. doi: 10.12998/wjcc.v6.i3.27
Review and update on the molecular basis of Leber congenital amaurosis  
Oscar Francisco Chacon-Camacho, Juan Carlos Zenteno 
World J Clin Cases 3(2):112-124. Published online Feb 16, 2015. doi: 10.12998/wjcc.v3.i2.112
Relational coordination and healthcare management in lung cancer  
José Antonio Vinagre Romero, Juan Del Llano Señarís, Carmen De Pablos Heredero, Mark Nuijten 
World J Clin Cases 2(12):757-768. Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.757
Combined surgical-orthodontic rehabilitation of cleidocranial dysplasia: 5 years follow-up  
Emre Çimen, Ömür Dereci, Ayşegül Mine Tüzüner-Öncül, Duygu Yazıcıoğlu, Erhan Özdiler, Aslı Şenol, Nejat Bora Sayan 
World J Clin Cases 3(8):751-756. Published online Aug 16, 2015. doi: 10.12998/wjcc.v3.i8.751
Treatment of laryngopharyngeal reflux disease: A systematic review  
Jerome R Lechien, Francois Mouawad, Maria R Barillari, Andrea Nacci, Seyyedeh Maryam Khoddami, Necati Enver, Sampath Kumar Raghunandhan, Christian Calvo-Henriquez, Young-Gyu Eun, Sven Saussez 
World J Clin Cases 7(19):2995-3011. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2995
Synovial sarcoma in the plantar region: A case report and literature review  
Jie Gao, Yu-Song Yuan, Ting Liu, Hao-Run Lv, Hai-Lin Xu 
World Journal of Clinical Cases 7(17):2549-2555. Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2549