Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2015; 3(5): 430-441
Published online May 16, 2015. doi: 10.12998/wjcc.v3.i5.430
Tick-borne encephalitis: A review of epidemiology, clinical characteristics, and management
Petra Bogovic, Franc Strle
Petra Bogovic, Franc Strle, Department of Infectious Diseases, University Medical Center Ljubljana, 1525 Ljubljana, Slovenia
Author contributions: Both authors approved the final version of the manuscript before submission.
Conflict-of-interest: The authors declare that they have no competing interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Petra Bogovic, MD, Department of Infectious Diseases, University Medical Center Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.
Telephone: +386-1-5222110 Fax: +386-1-5222456
Received: July 23, 2014
Peer-review started: July 25, 2014
First decision: August 28, 2014
Revised: September 18, 2014
Accepted: March 5, 2015
Article in press: March 9, 2015
Published online: May 16, 2015
Core Tip

Core tip: Tick-borne encephalitis (TBE) is the most common tick-borne central nervous system infection in Europe and Asia. It is caused by three subtypes of TBE virus: European, Siberian and Far-Eastern. Because of relatively severe clinical course, the absence of etiologic treatment, considerable proportion of patients with incomplete recovery after acute illness, as well as due to increasing incidence it represents a growing public health problem that could be substantially reduced with vaccination.