Published online May 16, 2015. doi: 10.12998/wjcc.v3.i5.430
Peer-review started: July 25, 2014
First decision: August 28, 2014
Revised: September 18, 2014
Accepted: March 5, 2015
Article in press: March 9, 2015
Published online: May 16, 2015
Core tip: Tick-borne encephalitis (TBE) is the most common tick-borne central nervous system infection in Europe and Asia. It is caused by three subtypes of TBE virus: European, Siberian and Far-Eastern. Because of relatively severe clinical course, the absence of etiologic treatment, considerable proportion of patients with incomplete recovery after acute illness, as well as due to increasing incidence it represents a growing public health problem that could be substantially reduced with vaccination.