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Open-Access Journal
Editorial
Metastatic gastric cancer treatment: Second line and beyond 
Marwan Ghosn, Samer Tabchi, Hampig Raphael Kourie, Mustapha Tehfe 
World J Gastroenterol 22(11):3069-3077. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3069
Review
Comparison of pediatric and adult antibiotic-associated diarrhea and Clostridium difficile infections 
Lynne Vernice McFarland, Metehan Ozen, Ener Cagri Dinleyici, Shan Goh 
World J Gastroenterol 22(11):3078-3104. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3078
Multidisciplinary management of nonfunctional neuroendocrine tumor of the pancreas 
Ian W Folkert, Paul Hernandez, Robert E Roses 
World J Gastroenterol 22(11):3105-3116. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3105
Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer 
Jonathan Landy, Emma Ronde, Nick English, Sue K Clark, Ailsa L Hart, Stella C Knight, Paul J Ciclitira, Hafid Omar Al-Hassi 
World J Gastroenterol 22(11):3117-3126. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3117
Evidence-based medical oncology and interventional radiology paradigms for liver-dominant colorectal cancer metastases 
Alan Alper Sag, Fatih Selcukbiricik, Nil Molinas Mandel 
World J Gastroenterol 22(11):3127-3149. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3127
Minireviews
Effective treatment of gastrointestinal bleeding with thalidomide - Chances and limitations 
Juergen Bauditz 
World J Gastroenterol 22(11):3158-3164. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3158
Basic Study
Hepatitis B and D viruses replication interference: Influence of hepatitis B genotype 
Antonio Madejón, Míriam Romero, Ángela Hernández, Araceli García-Sánchez, Marta Sánchez-Carrillo, Antonio Olveira, Javier García-Samaniego 
World J Gastroenterol 22(11):3165-3174. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3165
Astragalus polysaccharide attenuates rat experimental colitis by inducing regulatory T cells in intestinal Peyer’s patches 
Hai-Mei Zhao, Yan Wang, Xiao-Ying Huang, Min-Fang Huang, Rong Xu, Hai-Yang Yue, Bu-Gao Zhou, Hong-Yan Huang, Qi-Meng Sun, Duan-Yong Liu 
World J Gastroenterol 22(11):3175-3185. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3175
Melittin induces human gastric cancer cell apoptosis via activation of mitochondrial pathway 
Gui-Mei Kong, Wen-Hua Tao, Ya-Li Diao, Peng-Hua Fang, Ji-Jun Wang, Ping Bo, Feng Qian 
World J Gastroenterol 22(11):3186-3195. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3186
Retrospective Cohort Study
Predictors of re-bleeding after endoscopic hemostasis for delayed post-endoscopic sphincterotomy bleeding 
Mu-Hsien Lee, Yung-Kuan Tsou, Cheng-Hui Lin, Ching-Song Lee, Nai-Jen Liu, Kai-Feng Sung, Hao-Tsai Cheng 
World J Gastroenterol 22(11):3196-3201. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3196
Retrospective Study
Epithelial turnover in duodenal familial adenomatous polyposis: A possible role for estrogen receptors? 
Alfredo Di Leo, Gabriella Nesi, Mariabeatrice Principi, Domenico Piscitelli, Bruna Girardi, Maria Pricci, Giuseppe Losurdo, Andrea Iannone, Enzo Ierardi, Francesco Tonelli 
World J Gastroenterol 22(11):3202-3211. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3202
Comparison of hepatic venous pressure gradient and endoscopic grading of esophageal varices 
EunJi Lee, Yong Jae Kim, Dong Erk Goo, Seung Boo Yang, Hyun-Joo Kim, Jae Young Jang, Soung Won Jeong 
World J Gastroenterol 22(11):3212-3219. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3212
Is forceps more useful than visualization for measurement of colon polyp size? 
Jae Hyun Kim, Seun Ja Park, Jong Hoon Lee, Tae Oh Kim, Hyun Jin Kim, Hyung Wook Kim, Sang Heon Lee, Dong Hoon Baek, Busan Ulsan Gyeongnam Intestinal Study Group Society (BIGS) 
World J Gastroenterol 22(11):3220-3226. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3220
Association of Fusobacterium nucleatum infection with colorectal cancer in Chinese patients 
Yu-Yuan Li, Quan-Xing Ge, Jie Cao, Yong-Jian Zhou, Yan-Lei Du, Bo Shen, Yu-Jui Yvonne Wan, Yu-Qiang Nie 
World J Gastroenterol 22(11):3227-3233. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3227
Negative short-term impact of intraoperative biliary lavage in patients with hepatolithiasis 
Ou Jiang, Rong-Xing Zhou, Ke Yang, Chun-Xian Cai, Yu Liu, Nan-Sheng Cheng 
World J Gastroenterol 22(11):3234-3241. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3234
Application of gemstone spectral imaging for efficacy evaluation in hepatocellular carcinoma after transarterial chemoembolization 
Qi-Yu Liu, Chuan-Dong He, Ying Zhou, Dan Huang, Hua Lin, Zhong Wang, Dong Wang, Jin-Qiu Wang, Li-Ping Liao 
World J Gastroenterol 22(11):3242-3251. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3242
Observational Study
Constipation, hard stools, fecal urgency, and incomplete evacuation, but not diarrhea is associated with diabetes and its related factors 
Noriko Ihana-Sugiyama, Naoyoshi Nagata, Ritsuko Yamamoto-Honda, Eiko Izawa, Hiroshi Kajio, Takuro Shimbo, Masafumi Kakei, Naomi Uemura, Junichi Akiyama, Mitsuhiko Noda 
World J Gastroenterol 22(11):3252-3260. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3252
Clinical features, endoscopic polypectomy and STK11 gene mutation in a nine-month-old Peutz-Jeghers syndrome Chinese infant 
Zhi-Heng Huang, Zai Song, Ping Zhang, Jie Wu, Ying Huang 
World J Gastroenterol 22(11):3261-3267. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3261
Mutations in pre-core and basic core promoter regions of hepatitis B virus in chronic hepatitis B patients 
Xiao-Ling Wang, Jian-Ping Ren, Xue-Qing Wang, Xiao-Hong Wang, Shao-Fang Yang, Yi Xiong 
World J Gastroenterol 22(11):3268-3274. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3268
Prospective Study
Dual-sugar tests of small intestinal permeability are poor predictors of bacterial infections and mortality in cirrhosis: A prospective study 
Anika Vogt, Philipp A Reuken, Sven Stengel, Andreas Stallmach, Tony Bruns 
World J Gastroenterol 22(11):3275-3284. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3275
Case Report
Contained colonic perforation due to cecal retroflexion 
Zhuo Geng, Deepak Agrawal, Amit G Singal, Stephen Kircher, Samir Gupta 
World J Gastroenterol 22(11):3285-3288. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3285
Delayed diagnosis of alpha-1-antitrypsin deficiency following post-hepatectomy liver failure: A case report 
Benjamin Norton, Jemimah Denson, Christopher Briggs, Matthew Bowles, David Stell, Somaiah Aroori 
World J Gastroenterol 22(11):3289-3295. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3289
Primary advanced esophago-gastric melanoma: A rare case 
Lin Wang, Liang Zong, Hidetsugu Nakazato, Wen-Yue Wang, Chao-Feng Li, Yan-Fen Shi, Guo-Chao Zhang, Tao Tang 
World J Gastroenterol 22(11):3296-3301. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3296
Letters To The Editor
Liuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism? 
Kuo Du, Hartmut Jaeschke 
World J Gastroenterol 22(11):3302-3304. Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3302