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Open-Access Journal
Editorial
Gastrointestinal cancers in the era of theranostics: Updates and future perspectives 
Marwan Ghosn, Hampig Raphael Kourie, Samer Tabchi 
World J Gastroenterol 21(28):8473-8477. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8473
Topic Highlight
Current and future treatments for hepatocellular carcinoma 
Alexander Schlachterman, Willie W Craft Jr, Eric Hilgenfeldt, Avir Mitra, Roniel Cabrera 
World J Gastroenterol 21(28):8478-8491. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8478
Hepatitis C virus comes for dinner: How the hepatitis C virus interferes with autophagy 
Daniela Ploen, Eberhard Hildt 
World J Gastroenterol 21(28):8492-8507. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8492
Review
Gastroesophageal reflux and congenital gastrointestinal malformations 
Lucia Marseglia, Sara Manti, Gabriella D’Angelo, Eloisa Gitto, Carmelo Salpietro, Antonio Centorrino, Gianfranco Scalfari, Giuseppe Santoro, Pietro Impellizzeri, Carmelo Romeo 
World J Gastroenterol 21(28):8508-8515. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8508
Alcohol liver disease: A review of current therapeutic approaches to achieve long-term abstinence 
María Luisa Gutiérrez García, Sara Blasco-Algora, Conrado M Fernández-Rodríguez 
World J Gastroenterol 21(28):8516-8526. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8516
Circulating RNAs as new biomarkers for detecting pancreatic cancer 
Takahiro Kishikawa, Motoyuki Otsuka, Motoko Ohno, Takeshi Yoshikawa, Akemi Takata, Kazuhiko Koike 
World J Gastroenterol 21(28):8527-8540. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8527
Benign liver tumors in pediatric patients - Review with emphasis on imaging features 
Liliana Chiorean, Xin-Wu Cui, Andrea Tannapfel, Doris Franke, Martin Stenzel, Wojciech Kosiak, Dagmar Schreiber-Dietrich, Jörg Jüngert, Jian-Min Chang, Christoph F Dietrich 
World J Gastroenterol 21(28):8541-8561. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8541
Minireviews
MicroRNA expression in hepatitis C virus-related malignancies: A brief review 
Laura Gragnani, Alessia Piluso, Elisa Fognani, Anna Linda Zignego 
World J Gastroenterol 21(28):8562-8568. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8562
Basic Study
Association of hepatocyte-derived growth factor receptor/caudal type homeobox 2 co-expression with mucosal regeneration in active ulcerative colitis 
Ferenc Sipos, Miklós Constantinovits, Gábor Valcz, Zsolt Tulassay, Györgyi Műzes 
World J Gastroenterol 21(28):8569-8579. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8569
Restraint stress induces and exacerbates intestinal inflammation in interleukin-10 deficient mice 
Seong-Joon Koh, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Joo Sung Kim 
World J Gastroenterol 21(28):8580-8587. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8580
Overexpression of chaperonin containing TCP1, subunit 3 predicts poor prognosis in hepatocellular carcinoma 
Xiao Cui, Zhi-Ping Hu, Zhao Li, Peng-Ji Gao, Ji-Ye Zhu 
World J Gastroenterol 21(28):8588-8604. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8588
Linked PNPLA3 polymorphisms confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B 
Qin Pan, Rui-Nan Zhang, Yu-Qin Wang, Rui-Dan Zheng, Yu-Qiang Mi, Wen-Bin Liu, Feng Shen, Guang-Yu Chen, Jia-Fa Lu, Chan-Yan Zhu, Shu-Yi Zhang, Yi-Ming Chen, Wan-Lu Sun, Jian-Gao Fan 
World J Gastroenterol 21(28):8605-8614. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8605
TLR4 upregulates CBS expression through NF-κB activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity 
Bo Yuan, Wei-Hong Tang, Li-Juan Lu, Yuan Zhou, Hong-Yan Zhu, You-Lang Zhou, Hong-Hong Zhang, Chuang-Ying Hu, Guang-Yin Xu 
World J Gastroenterol 21(28):8615-8628. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8615
Newly designed “pieced” stent in a rabbit model of benign esophageal stricture 
Jin Liu, Liang Shang, Ji-Yong Liu, Cheng-Yong Qin 
World J Gastroenterol 21(28):8629-8635. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8629
Retrospective Study
Clinical characteristics of Helicobacter pylori-negative drug-negative peptic ulcer bleeding 
Woo Chul Chung, Eun Jung Jeon, Dae Bum Kim, Hea Jung Sung, Yeon-Ji Kim, Eun Sun Lim, Min-ah Kim, Jung Hwan Oh 
World J Gastroenterol 21(28):8636-8643. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8636
Aggressive surgical resection does not improve survival in operable esophageal squamous cell carcinoma with N2-3 status 
Yu-Zhen Zheng, Wei Zhao, Yi Hu, Xiao-Xiao Ding-Lin, Jing Wen, Hong Yang, Qian-Wen Liu, Kong-Jia Luo, Qing-Yuan Huang, Jun-Ying Chen, Jian-Hua Fu 
World J Gastroenterol 21(28):8644-8652. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8644
Hepatitis B surface antigen levels of cessation of nucleos(t)ide analogs associated with virological relapse in hepatitis B surface antigen-negative chronic hepatitis B patients 
Guo-Hong Ge, Yun Ye, Xin-Bei Zhou, Li Chen, Cong He, Dan-Feng Wen, You-Wen Tan 
World J Gastroenterol 21(28):8653-8659. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8653
Prospective Study
Boceprevir early-access for advanced-fibrosis/cirrhosis in Asia-pacific hepatitis C virus genotype 1 non-responders/relapsers 
Wattana Sukeepaisarnjaroen, Tri Pham, Tewesak Tanwandee, Saroja Nazareth, Sam Galhenage, Lindsay Mollison, Leanne Totten, Alan Wigg, Rosalie Altus, Anton Colman, Brenda Morales, Sue Mason, Tracey Jones, Nadine Leembruggen, Vince Fragomelli, Cheryl Sendall, Richard Guan, Dede Sutedja, Soek Siam Tan, Yock Young Dan, Yin Mei Lee, Widjaja Luman, Eng Kiong Teo, Yin Min Than, Teerha Piratvisuth, Seng Gee Lim 
World J Gastroenterol 21(28):8660-8669. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8660
Systematic Reviews
Current state of laparoscopic parastomal hernia repair: A meta-analysis 
Francis J DeAsis, Brittany Lapin, Matthew E Gitelis, Michael B Ujiki 
World J Gastroenterol 21(28):8670-8677. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8670
Screening for pancreatic cancer in familial high-risk individuals: A systematic review 
Chao Lu, Cheng-Fu Xu, Xing-Yong Wan, Hua-Tuo Zhu, Chao-Hui Yu, You-Ming Li 
World J Gastroenterol 21(28):8678-8686. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8678
Meta-Analysis
Correlation of human epidermal growth factor receptor protein expression and colorectal cancer 
Wen-Juan Yang, Xing-Jie Shen, Xiao-Xia Ma, Zhi-Gang Tan, Yan Song, Yi-Tong Guo, Mei Yuan 
World J Gastroenterol 21(28):8687-8696. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8687
Autologous bone marrow transplantation in decompensated liver: Systematic review and meta-analysis 
Prasoon Pankaj, Qi Zhang, Xue-Li Bai, Ting-Bo Liang 
World J Gastroenterol 21(28):8697-8710. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8697
Interleukin-18 genetic polymorphisms contribute differentially to the susceptibility to Crohn’s disease 
Su-Jun Gao, Li Zhang, Wei Lu, Lu Wang, Lei Chen, Zhen Zhu, Hai-Hang Zhu 
World J Gastroenterol 21(28):8711-8722. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8711
Case Report
Conservative reconstruction using stents as salvage therapy for disruption of esophago-gastric anastomosis 
Taro Oshikiri, Yoshinobu Yamamoto, Ikuya Miki, Masahiro Tsuda, Tetsu Nakamura, Yasuhiro Fujino, Masahiro Tominaga, Yoshihiro Kakeji 
World J Gastroenterol 21(28):8723-8729. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8723
Hepatic inflammatory pseudotumor presenting in an 8-year-old boy: A case report and review of literature 
Hussa Al-Hussaini, Haya Azouz, Ahmed Abu-Zaid 
World J Gastroenterol 21(28):8730-8738. Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8730