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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
1
New biomarkers for clinical management of hepatitis C virus infected patients  
Alessandra Biasiolo, Andrea Martini, Patrizia Pontisso 
World J Clin Infect Dis 5(4):59-66. Published online Nov 25, 2015. doi: 10.5495/wjcid.v5.i4.59
2
Statins as antifungal agents  
László Galgóczy, Ildikó Nyilasi, Tamás Papp, Csaba Vágvölgyi 
World J Clin Infect Dis 1(1):4-10. Published online Dec 30, 2011. doi: 10.5495/wjcid.v1.i1.4
3
Interplay between rabies virus and the mammalian immune system  
Nicholas Johnson, Adam F Cunningham 
World J Clin Infect Dis 5(4):67-76. Published online Nov 25, 2015. doi: 10.5495/wjcid.v5.i4.67
4
Reverse genetics: Unlocking the secrets of negative sense RNA viral pathogens  
Kathryn Edenborough, Glenn A Marsh 
World J Clin Infect Dis 4(4):16-26. Published online Nov 25, 2014. doi: 10.5495/wjcid.v4.i4.16
5
Platelet indices in neonatal sepsis: A review  
Ramesh Bhat Y 
World J Clin Infect Dis 7(1):6-10. Published online Feb 25, 2017. doi: 10.5495/wjcid.v7.i1.6
6
Surface adhesion and host response as pathogenicity factors of Neisseria meningitidis  
Jose Uberos, M Molina-Oya, S Martinez-Serrano, L Fernández-López 
World J Clin Infect Dis 5(2):37-43. Published online May 25, 2015. doi: 10.5495/wjcid.v5.i2.37
7
Acinetobacter baumannii: An emerging pathogenic threat to public health  
Suresh G Joshi, Geetanjali M Litake 
World J Clin Infect Dis 3(3):25-36. Published online Aug 25, 2013. doi: 10.5495/wjcid.v3.i3.25
8
Disseminated cryptosporidiosis: Case report and literature review  
Shehla Khalil, Bijay R Mirdha, Jaishree Paul, Ashutosh Panda, Yogita Singh 
World J Clin Infect Dis 7(2):32-37. Published online May 25, 2017. doi: 10.5495/wjcid.v7.i2.32
9
Improvement in human immunodeficiency virus-1/acquired immune deficiency syndrome patients’ well-being following administration of “Phyto V7”  
Ruben Wernik, Jose L Priore, Walter F Goldman, Adriana del Carmen Elias, Gadi Borkow 
World J Clin Infect Dis 5(2):44-50. Published online May 25, 2015. doi: 10.5495/wjcid.v5.i2.44
10
Leptospirosis: A clinical review of evidence based diagnosis, treatment and prevention  
Alison B Lane, Michael M Dore 
World J Clin Infect Dis 6(4):61-66. Published online Nov 25, 2016. doi: 10.5495/wjcid.v6.i4.61
11
Management of periprosthetic infections  
Félix Vilchez-Cavazos, Gregorio Villarreal-Villarreal, Victor Peña-Martinez, Carlos Acosta-Olivo 
World J Clin Infect Dis 7(2):11-20. Published online May 25, 2017. doi: 10.5495/wjcid.v7.i2.11
12
Antioxidant enzyme profile of two clinical isolates of Entamoeba histolytica varying in sensitivity to antiamoebic drugs  
Lakshmi Rani Iyer, Neha Banyal, Shailendra Naik, Jaishree Paul 
World J Clin Infect Dis 7(2):21-31. Published online May 25, 2017. doi: 10.5495/wjcid.v7.i2.21
13
Clinical research in febrile neutropenia in cancer patients: Past achievements and perspectives for the future  
Jean Klastersky, Marianne Paesmans, Michel Aoun, Aspasia Georgala, Angela Loizidou, Yassine Lalami, Lissandra Dal Lago 
World J Clin Infect Dis 6(3):37-60. Published online Aug 25, 2016. doi: 10.5495/wjcid.v6.i3.37
14
Systems biology applications to study mechanisms of human immunodeficiency virus latency and reactivation  
Cory H White, Bastiaan Moesker, Angela Ciuffi, Nadejda Beliakova-Bethell 
World J Clin Infect Dis 6(2):6-21. Published online May 25, 2016. doi: 10.5495/wjcid.v6.i2.6
15
Treatment of methicillin-resistant Staphylococcus aureus infections: Importance of high vancomycin minumum inhibitory concentrations  
Alejandra Morales-Cartagena, Antonio Lalueza, Francisco López-Medrano, Rafael San Juan, José María Aguado 
World J Clin Infect Dis 5(2):14-29. Published online May 25, 2015. doi: 10.5495/wjcid.v5.i2.14
16
17
New tools, new tick-borne diseases?  
Aránzazu Portillo, José A Oteo 
World J Clin Infect Dis 5(3):51-54. Published online Aug 25, 2015. doi: 10.5495/wjcid.v5.i3.51
18
Subversion of cellular stress responses by poxviruses  
Thiago Lima Leão, Flávio Guimarães da Fonseca 
World J Clin Infect Dis 4(4):27-40. Published online Nov 25, 2014. doi: 10.5495/wjcid.v4.i4.27
19
Pneumococcal disease in adult solid organ transplantation recipients  
Cristina Roca-Oporto, María Eugenia Pachón-Ibañez, Jerónimo Pachón, Elisa Cordero 
World J Clin Infect Dis 5(1):1-10. Published online Feb 25, 2015. doi: 10.5495/wjcid.v5.i1.1
20
Is it enough to eliminate hepatitis C virus to reverse the damage caused by the infection?  
Patricia Pérez-Matute, José A Oteo 
World J Clin Infect Dis 7(1):1-5. Published online Feb 25, 2017. doi: 10.5495/wjcid.v7.i1.1
21
Non chylous filarial ascites: A rare case report  
Kaivan S Shah, Prasad A Bhate, Dattatray Solanke, Vikas Pandey, Meghraj A Ingle, Shubhada V Kane, Prabha Sawant 
World J Clin Infect Dis 5(1):11-13. Published online Feb 25, 2015. doi: 10.5495/wjcid.v5.i1.11
22
Origin of de novo daptomycin non susceptible enterococci  
Theodoros Kelesidis 
World J Clin Infect Dis 5(2):30-36. Published online May 25, 2015. doi: 10.5495/wjcid.v5.i2.30
23
Healthcare seeking trends in acute respiratory infections among children of Pakistan  
Hana Mahmood, Samina Mohsin Khan, Saleem Abbasi, Yahya Sheraz 
World J Clin Infect Dis 7(3):38-45. Published online Aug 25, 2017. doi: 10.5495/wjcid.v7.i3.38
24
Autoimmune hepatitis in human immunodeficiency virus infection: Case report and literature review  
Ivan Noreña, Jairo A Morantes-Caballero, Andrés Garcés, Brian José Gómez, Gabriel Rodríguez, Carlos Saavedra, William Otero 
World J Clin Infect Dis 7(4):50-57. Published online Nov 25, 2017. doi: 10.5495/wjcid.v7.i4.50
25
Regulation of fim genes in uropathogenic Escherichia coli  
William R Schwan 
World J Clin Infect Dis 1(1):17-25. Published online Dec 30, 2011. doi: 10.5495/wjcid.v1.i1.17
26
Prosthetic joint infections-a clinico-microbiological perspective: Review article  
Pravin K Nair, Vivek G Bhat, Michelle S Vaz 
World J Clin Infect Dis 4(3):9-15. Published online Aug 25, 2014. doi: 10.5495/wjcid.v4.i3.9
27
Osmolyte transport in Staphylococcus aureus and the role in pathogenesis  
William R Schwan, Keith J Wetzel 
World J Clin Infect Dis 6(2):22-27. Published online May 25, 2016. doi: 10.5495/wjcid.v6.i2.22
28
Tuberculosis and hematopoietic stem cell transplant: Review of a difficult and often underestimated problem  
Guadalupe García-Elorriaga, Guillermo del Rey-Pineda 
World J Clin Infect Dis 3(4):70-78. Published online Nov 25, 2013. doi: 10.5495/wjcid.v3.i4.70
29
Challenges in management of recurrent and refractory Clostridium difficile infection  
Anne M Meehan, Raseen Tariq, Sahil Khanna 
World J Clin Infect Dis 6(3):28-36. Published online Aug 25, 2016. doi: 10.5495/wjcid.v6.i3.28
30
Transcribing virulence in Staphylococcus aureus  
Jennifer M Junecko, Agnieszka K Zielinska, Lara N Mrak, Douglas C Ryan, Justin W Graham, Mark S Smeltzer, Chia Y Lee 
World J Clin Infect Dis 2(4):63-76. Published online Aug 25, 2012. doi: 10.5495/wjcid.v2.i4.63
31
Is there an unrecognised role for Campylobacter infections in (chronic) inflammatory diseases?  
Rogier Louwen, John P Hays 
World J Clin Infect Dis 3(4):58-69. Published online Nov 25, 2013. doi: 10.5495/wjcid.v3.i4.58
32
Tuf mRNA rather than 16S rRNA is associated with culturable Staphylococcus aureus  
Anne JM Loonen, Petra FG Wolffs, Maikel de Bresser, Maurice Habraken, Cathrien A Bruggeman, Mirjam HA Hermans, Adriaan JC van den Brule 
World J Clin Infect Dis 5(4):86-93. Published online Nov 25, 2015. doi: 10.5495/wjcid.v5.i4.86
33
Epidemiological perspective of drug resistant extrapulmonary tuberculosis  
Pravin Kumar Singh, Amita Jain 
World J Clin Infect Dis 5(4):77-85. Published online Nov 25, 2015. doi: 10.5495/wjcid.v5.i4.77
34
Atypical manifestation of herpes esophagitis in an immunocompetent patient: Case report and literature review  
Fabiola C Rios de Choudens, Sajiv Sethi, Shuchi Pandya, Sowmya Nanjappa, John N Greene 
World J Clin Infect Dis 7(3):46-49. Published online Aug 25, 2017. doi: 10.5495/wjcid.v7.i3.46
35
National preparedness training and exercises for Ebola cases in the United Kingdom  
Andrew D Black, Hilary J Moulsdale, Mark R Evans, John L Simpson 
World J Clin Infect Dis 6(1):1-5. Published online Feb 25, 2016. doi: 10.5495/wjcid.v6.i1.1
36
How could we reduce antifungal use in the intensive care unit?  
Anahita Rouzé, Karim Jaffal, Saad Nseir 
World J Clin Infect Dis 5(4):55-58. Published online Nov 25, 2015. doi: 10.5495/wjcid.v5.i4.55
37
Unsuspected imported malaria in a case of sudden infant death  
Teresa Pusiol, Anna Maria Lavezzi, Ferdinando Radice, Graziella Alfonsi, Luigi Matturri 
World J Clin Infect Dis 4(2):5-8. Published online May 25, 2014. doi: 10.5495/wjcid.v4.i2.5
38
Fighting nosocomial infections with biocidal non-intrusive hard and soft surfaces  
Gadi Borkow, Alastair Monk 
World J Clin Infect Dis 2(4):77-90. Published online Aug 25, 2012. doi: 10.5495/wjcid.v2.i4.77
39
Extended role for insertion sequence elements in the antibiotic resistance of Bacteroides  
József Sóki 
World J Clin Infect Dis 3(1):1-12. Published online Feb 25, 2013. doi: 10.5495/wjcid.v3.i1.1
40
Primary lymphocutaneous nocardiosis associated with gardening: A case series  
Giorgio Tarchini, Frederick S Ross 
World J Clin Infect Dis 3(4):86-89. Published online Nov 25, 2013. doi: 10.5495/wjcid.v3.i4.86
41
Gastric mucormycosis: A case report  
Mpho Klaas Kgomo, Ali Ahmed Elnagar, Kgataki Mashoshoe, P Thomas, W G Van Hougenhouck-Tulleken 
World J Clin Infect Dis 8(1):1-3. Published online Feb 25, 2018. doi: 10.5495/wjcid.v8.i1.1
42
Can the detection of IgA anti-Mycoplasma pneumoniae added to IgM increase diagnostic accuracy in patients with infections of the lower respiratory airways?  
Massimo De Paschale, Teresa Cerulli, Debora Cagnin, Alessia Paganini, Maria Teresa Manco, Luisa Belvisi, Cristina Morazzoni, Laura Marinoni, Carlo Agrappi, Paola Mirri, Pierangelo Clerici 
World J Clin Infect Dis 6(4):67-72. Published online Nov 25, 2016. doi: 10.5495/wjcid.v6.i4.67
43
Physiological functions and clinical implications of fibrinogen-like 2: A review  
Genyan Yang, W Craig Hooper 
World J Clin Infect Dis 3(3):37-46. Published online Aug 25, 2013. doi: 10.5495/wjcid.v3.i3.37
44
Role of chemokines and cytokines in the neuropathogenesis of African trypanosomiasis  
Willias Masocha 
World J Clin Infect Dis 3(4):79-85. Published online Nov 25, 2013. doi: 10.5495/wjcid.v3.i4.79
45
Medical errors, infection-control breaches and the use of adulterated and misbranded medical devices  
Lawrence F Muscarella 
World J Clin Infect Dis 2(2):13-27. Published online Apr 25, 2012. doi: 10.5495/wjcid.v2.i2.13
46
Sub-acute endocarditis by Corynebacterium straitum: An often ignored pathogen  
Vratika Agarwal, Valay Parikh, Mayur Lakhani, Chitradeep De, Apurva Motivala, Neville Mobarakai 
World J Clin Infect Dis 4(1):1-4. Published online Feb 25, 2014. doi: 10.5495/wjcid.v4.i1.1
47
Pharmacodynamics for predicting therapeutic outcome and countering resistance spread: The cefditoren case  
Francisco Soriano, María-José Giménez, Lorenzo Aguilar 
World J Clin Infect Dis 2(3):28-38. Published online Jun 25, 2012. doi: 10.5495/wjcid.v2.i3.28
48
Liver biopsy for visceral leishmaniasis diagnosis in pregnancy: report of 2 cases  
Talles Bazeia Lima, Clarissa Ribeiro Villar, Maria Aparecida Marchesan Rodrigues, Júlio Pinheiro Baima, Fábio da Silva Yamashiro, Letícia Campos Franzoni, Carlos Antonio Caramori, Giovanni Faria Silva, Fernando Gomes Romeiro, Lígia Yukie Sassaki 
World J Clin Infect Dis 3(2):20-24. Published online May 25, 2013. doi: 10.5495/wjcid.v3.i2.20
49
Natural contamination of human hands with enteric parasites in Indian Subcontinent  
M Khalid Ijaz, Kaisar A Talukder, Mohammad Aslam, Rashidul Haque, Sandipan Ganguly, Ishrat J Azmi, Md Shawkat Hossain, Avik Kumar Mukherjee, Dibyendu Raj, Ijaz Ahmed, Jabeen Kamal, Joseph R Rubino, Alam Nur-E-Kamal 
World J Clin Infect Dis 3(2):13-19. Published online May 25, 2013. doi: 10.5495/wjcid.v3.i2.13
50
Microbial translocation, residual viremia and immune senescence in the pathogenesis of HIV-1 infection  
Alessandra Fantauzzi, Francesca Falasca, Gabriella d’Ettorre, Eugenio Nelson Cavallari, Ombretta Turriziani, Vincenzo Vullo, Ivano Mezzaroma 
World J Clin Infect Dis 3(4):47-57. Published online Nov 25, 2013. doi: 10.5495/wjcid.v3.i4.47