Kgomo MK, Elnagar AA, Mashoshoe K, Thomas P, Van Hougenhouck-Tulleken WG. Gastric mucormycosis: A case report. World J Clin Infect Dis 2018; 8(1): 1-3 [DOI: 10.5495/wjcid.v8.i1.1]
Corresponding Author of This Article
Mpho Klaas Kgomo, Professor, Department of Gastroenterology, University of Pretoria, Bophelo Street, Gezina, Pretoria 0001, Gauteng Province, South Africa. mpho.kgomo@up.ac.za
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Infect Dis. Feb 25, 2018; 8(1): 1-3 Published online Feb 25, 2018. doi: 10.5495/wjcid.v8.i1.1
Gastric mucormycosis: A case report
Mpho Klaas Kgomo, Ali Ahmed Elnagar, Kgataki Mashoshoe, P Thomas, W G Van Hougenhouck-Tulleken
Mpho Klaas Kgomo, Ali Ahmed Elnagar, Kgataki Mashoshoe, P Thomas, W G Van Hougenhouck-Tulleken, Department of Gastroenterology, University of Pretoria, Pretoria 0001, Gauteng Province, South Africa
Author contributions: Kgomo MK was involved in the write-up and submission of the case report, patient care and interpretation of the literature; Elnagar AA, Mashoshoe K, Thomas P and Van Hougenhouck-Tulleken WG was involved in the collection of data, patient care and interpretation of test results.
Informed consent statement: The patient involved in this study gave her written informed consent authorizing use and disclosure of her protected health information.
Conflict-of-interest statement: Dr. Kgomo has nothing to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Mpho Klaas Kgomo, Professor, Department of Gastroenterology, University of Pretoria, Bophelo Street, Gezina, Pretoria 0001, Gauteng Province, South Africa. mpho.kgomo@up.ac.za
Telephone: +27-12-3542246 Fax: +27-12-3220696
Received: September 14, 2017 Peer-review started: September 16, 2017 First decision: October 23, 2017 Revised: November 9, 2017 Accepted: November 27, 2017 Article in press: November 27, 2017 Published online: February 25, 2018
ARTICLE HIGHLIGHTS
Case characteristics
We present a 38 years old female seen in our hospital with a 2 wk history of productive cough dyspnoea and lethargy.
Clinical diagnosis
On clinical examination she had oral thrush, more than 1 cm cervical and axillary lymphadenopathy, pallor with an ejection systolic murmur, hypotension, tachycardia and respiratory failure.
Differential diagnosis
Differential diagnosis of human immunodeficiency virus infection with candidiasis, TB pneumonia and gastrointestinal bleed was made.
Laboratory diagnosis
She was found to have severe anemia, acquired immune deficiency syndrome with pneumonia, esophageal candidiasis and gastric mucormycosis and gastric bleed.
Imaging diagnosis
CXR showed multi-lobar pneumonia and gastroscopy showed gastric plaques as shown in Figure 1.
Pathological diagnosis
Gastric biopsy showed fungal hyphae consistent with mucormycosis as shown in Figure 2.
Treatment
She was started on anti-tuberculosis treatment, fluconazole broad spectrum antibiotics followed a few days later by amphotericin B.
Related reports
She failed to respond to fluconazole and only responded to amphotericin B.
Term explanation
Mucormycosis is an invasive fungal infection seen only in patients with reduced immune system.
Experiences and lessons
Mucormycosis infect the stomach and can co-exist with candida.
