Joshi SG, Litake GM. Acinetobacter baumannii: An emerging pathogenic threat to public health. World J Clin Infect Dis 2013; 3(3): 25-36 [DOI: 10.5495/wjcid.v3.i3.25]
Corresponding Author of This Article
Suresh G Joshi, MD, PhD, Surgical and Nosocomial Infections Research Program, Drexel University College of Medicine, 245 North 15th Street, Suite 7150, Mail 413, Philadelphia, PA 19102, United States. suresh.joshi@drexelmed.edu
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Review
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World J Clin Infect Dis. Aug 25, 2013; 3(3): 25-36 Published online Aug 25, 2013. doi: 10.5495/wjcid.v3.i3.25
Acinetobacter baumannii: An emerging pathogenic threat to public health
Suresh G Joshi, Geetanjali M Litake
Suresh G Joshi, Surgical and Nosocomial Infections Research Program, Drexel University College of Medicine, Philadelphia, PA 19102, United States
Geetanjali M Litake, Department of Biotechnology, Modern College, University of Pune affiliate, Pune 411007, India
Author contributions: Both authors have approved the final version of this manuscript and contributed to analysis and interpretation of data; Joshi SG contributed to the conception and design of the manuscript, acquisition of data, drafting the manuscript for intellectual content and modified version; Litake GM contributed to developing rough draft of the manuscript.
Correspondence to: Suresh G Joshi, MD, PhD, Surgical and Nosocomial Infections Research Program, Drexel University College of Medicine, 245 North 15th Street, Suite 7150, Mail 413, Philadelphia, PA 19102, United States. suresh.joshi@drexelmed.edu
Telephone: +1-215-7628431 Fax: +1-215-7628389
Received: June 21, 2013 Revised: July 26, 2013 Accepted: August 4, 2013 Published online: August 25, 2013
Core Tip
Core tip:Acinetobacter, is Gram-negative cocco-bacilli, originally regarded as low virulence bacteria, adopted now with increasing incidences, and recognized as a significant healthcare-associated multidrug-resistant classical pathogen. Acinetobacter baumannii (A. baumannii) accounts for nearly 80% of reported Acinetobacter infections. A. baumannii resist desiccation, and survive for several months on animate and inanimate surfaces. It has excellent colonizing potential, and contact transmission is a big challenge intermittent as well as endemic outbreaks. Strong biofilm formation is a part of virulence pathogenesis strategies of this organisms, and elimination of the identified source often require multiple interventions. This review mainly discusses on relevant epidemiological features of A. baumannii.
