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Open-Access Journal
Editorial
Gastroesophageal reflux disease and morbid obesity: To sleeve or not to sleeve? 
Fabrizio Rebecchi, Marco E Allaix, Marco G Patti, Francisco Schlottmann, Mario Morino 
World J Gastroenterol 23(13):2269-2275. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2269
Review
Advanced pancreatic ductal adenocarcinoma - Complexities of treatment and emerging therapeutic options 
Chandra Diwakarla, Katherine Hannan, Nadine Hein, Desmond Yip 
World J Gastroenterol 23(13):2276-2285. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2276
Minireviews
Indoleamine 2,3-dioxygenase: As a potential prognostic marker and immunotherapeutic target for hepatocellular carcinoma 
Kashif Asghar, Asim Farooq, Bilal Zulfiqar, Muhammad Usman Rashid 
World J Gastroenterol 23(13):2286-2293. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2286
Basic Study
Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice 
Takuhito Sezaki, Yuki Hirata, Teruki Hagiwara, Yuki I Kawamura, Tadashi Okamura, Rieko Takanashi, Kenta Nakano, Miwa Tamura-Nakano, Linda C Burkly, Taeko Dohi 
World J Gastroenterol 23(13):2294-2307. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2294
CMA down-regulates p53 expression through degradation of HMGB1 protein to inhibit irradiation-triggered apoptosis in hepatocellular carcinoma 
Jing-Hua Wu, Jia-Pei Guo, Jun Shi, Hui Wang, Lei-Lei Li, Bin Guo, Dian-Xing Liu, Qing Cao, Zhi-Yong Yuan 
World J Gastroenterol 23(13):2308-2317. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2308
Cullin 4A is associated with epithelial to mesenchymal transition and poor prognosis in perihilar cholangiocarcinoma 
Tong-Jun Zhang, Dong Xue, Cheng-De Zhang, Ze-Dong Zhang, Qing-Ran Liu, Jian-Qiang Wang 
World J Gastroenterol 23(13):2318-2329. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2318
Notch signaling mediated by TGF-β/Smad pathway in concanavalin A-induced liver fibrosis in rats 
Yi Wang, Ruo-Wu Shen, Bing Han, Zhen Li, Le Xiong, Feng-Yu Zhang, Bei-Bei Cong, Bei Zhang 
World J Gastroenterol 23(13):2330-2336. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2330
MicroRNA-145 exerts tumor-suppressive and chemo-resistance lowering effects by targeting CD44 in gastric cancer 
Jian-Feng Zeng, Xiao-Qiu Ma, Lin-Pei Wang, Wei Wang 
World J Gastroenterol 23(13):2337-2345. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2337
Case Control Study
Predictors for difficult cecal insertion in colonoscopy: The impact of obesity indices 
Soo Yun Moon, Byung Chang Kim, Dae Kyung Sohn, Kyung Su Han, Bun Kim, Chang Won Hong, Bum Joon Park, Kum Hei Ryu, Ji Hyung Nam 
World J Gastroenterol 23(13):2346-2354. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2346
Retrospective Cohort Study
Impact of interferon-free antivirus therapy on lipid profiles in patients with chronic hepatitis C genotype 1b 
Daisuke Endo, Kenichi Satoh, Noritomo Shimada, Atsushi Hokari, Yoshio Aizawa 
World J Gastroenterol 23(13):2355-2364. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2355
Retrospective Study
Transition after pediatric liver transplantation - Perceptions of adults, adolescents and parents 
Norman Junge, Katarina Migal, Imeke Goldschmidt, Ulrich Baumann 
World J Gastroenterol 23(13):2365-2375. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2365
Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery 
Amilcare Parisi, Daniel Reim, Felice Borghi, Ninh T Nguyen, Feng Qi, Andrea Coratti, Fabio Cianchi, Maurizio Cesari, Francesca Bazzocchi, Orhan Alimoglu, Johan Gagnière, Graziano Pernazza, Simone D’Imporzano, Yan-Bing Zhou, Juan-Santiago Azagra, Olivier Facy, Steven T Brower, Zhi-Wei Jiang, Lu Zang, Arda Isik, Alessandro Gemini, Stefano Trastulli, Alexander Novotny, Alessandra Marano, Tong Liu, Mario Annecchiarico, Benedetta Badii, Giacomo Arcuri, Andrea Avanzolini, Metin Leblebici, Denis Pezet, Shou-Gen Cao, Martine Goergen, Shu Zhang, Giorgio Palazzini, Vito D’Andrea, Jacopo Desiderio 
World J Gastroenterol 23(13):2376-2384. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2376
Clinical implication of FDG uptake of bone marrow on PET/CT in gastric cancer patients with surgical resection 
Jeong Won Lee, Moon-Soo Lee, Il Kwon Chung, Myoung Won Son, Young Sin Cho, Sang Mi Lee 
World J Gastroenterol 23(13):2385-2395. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2385
Observational Study
Safety and efficacy of tenofovir in chronic hepatitis B-related decompensated cirrhosis 
Soon Kyu Lee, Myeong Jun Song, Seok Hyun Kim, Byung Seok Lee, Tae Hee Lee, Young Woo Kang, Suk Bae Kim, Il Han Song, Hee Bok Chae, Soon Young Ko, Jae Dong Lee 
World J Gastroenterol 23(13):2396-2403. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2396
Can mean platelet volume play a role in evaluating the severity of acute pancreatitis? 
Jing-Jing Lei, Li Zhou, Qi Liu, Can Xiong, Chun-Fang Xu 
World J Gastroenterol 23(13):2404-2413. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2404
Prospective Study
Proposed criteria to differentiate heterogeneous eosinophilic gastrointestinal disorders of the esophagus, including eosinophilic esophageal myositis 
Hiroki Sato, Nao Nakajima, Kazuya Takahashi, Go Hasegawa, Ken-ichi Mizuno, Satoru Hashimoto, Satoshi Ikarashi, Kazunao Hayashi, Yutaka Honda, Junji Yokoyama, Yuichi Sato, Shuji Terai 
World J Gastroenterol 23(13):2414-2423. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2414
Therapeutic experience of 289 elderly patients with biliary diseases 
Zong-Ming Zhang, Zhuo Liu, Li-Min Liu, Chong Zhang, Hong-Wei Yu, Bai-Jiang Wan, Hai Deng, Ming-Wen Zhu, Zi-Xu Liu, Wen-Ping Wei, Meng-Meng Song, Yue Zhao 
World J Gastroenterol 23(13):2424-2434. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2424
Meta-Analysis
What is the quantitative risk of gastric cancer in the first-degree relatives of patients? A meta-analysis 
Mohammad Yaghoobi, Julia McNabb-Baltar, Raheleh Bijarchi, Richard H Hunt 
World J Gastroenterol 23(13):2435-2442. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2435
Case Report
Hepatic angiosarcoma with clinical and histological features of Kasabach-Merritt syndrome 
Sanya Wadhwa, Tae Hun Kim, Leah Lin, Gary Kanel, Takeshi Saito 
World J Gastroenterol 23(13):2443-2447. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2443
Letters To The Editor
Tumor biopsy and patient enrollment in clinical trials for advanced hepatocellular carcinoma 
Lorenza Rimassa, Maria Reig, Giovanni Abbadessa, Markus Peck-Radosavljevic, William Harris, Vittorina Zagonel, Davide Pastorelli, Elena Rota Caremoli, Camillo Porta, Nevena Damjanov, Hitendra Patel, Bruno Daniele, Maria Lamar, Brian Schwartz, Terri Goldberg, Armando Santoro, Jordi Bruix 
World J Gastroenterol 23(13):2448-2452. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2448