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Open-Access Journal
Editorial
Co-localization hypothesis: A mechanism for the intrapancreatic activation of digestive enzymes during the early phases of acute pancreatitis 
Gijs JD van Acker, George Perides, Michael L Steer 
World J Gastroenterol 12(13):1985-1990. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.1985
Review
Novel susceptibility genes in inflammatory bowel disease 
Colin Noble, Elaine Nimmo, Daniel Gaya, Richard K Russell, Jack Satsangi 
World J Gastroenterol 12(13):1991-1999. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.1991
Chemotherapy as a component of multimodal therapy for gastric carcinoma 
Yasuhiro Kodera, Michitaka Fujiwara, Masahiko Koike, Akimasa Nakao 
World J Gastroenterol 12(13):2000-2005. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2000
Esophageal Cancer
Expression of midkine and its clinical significance in esophageal squamous cell carcinoma 
Ying-Jia Ren, Qing-Yun Zhang 
World J Gastroenterol 12(13):2006-2010. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2006
Colorectal Cancer
Relationship between somatostatin receptor subtype expression and clinicopathology, Ki-67, Bcl-2 and p53 in colorectal cancer 
Cheng-Zhi Qiu, Chuan Wang, Zhong-Xin Huang, Shi-Ze Zhu, You-Yi Wu, Jian-Long Qiu 
World J Gastroenterol 12(13):2011-2015. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2011
Basic Research
Adeno-associated virus-mediated heme oxygenase-1 gene transfer suppresses the progression of micronodular cirrhosis in rats 
Tung-Yu Tsui, Chi-Keung Lau, Jian Ma, Gabriel Glockzin, Aiman Obed, Hans J Schlitt, Sheung-Tat Fan 
World J Gastroenterol 12(13):2016-2023. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2016
Rosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein 
Yuji Naito, Kazuhiro Katada, Tomohisa Takagi, Hisato Tsuboi, Masaaki Kuroda, Osamu Handa, Satoshi Kokura, Norimasa Yoshida, Hiroshi Ichikawa, Toshikazu Yoshikawa 
World J Gastroenterol 12(13):2024-2030. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2024
Usefulness of biopsying the major duodenal papilla to diagnose autoimmune pancreatitis: A prospective study using IgG4-immunostaining 
Terumi Kamisawa, Yuyang Tu, Hitoshi Nakajima, Naoto Egawa, Kouji Tsuruta, Atsutake Okamoto 
World J Gastroenterol 12(13):2031-2033. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2031
Effects of Aloe vera and sucralfate on gastric microcirculatory changes, cytokine levels and gastric ulcer healing in rats 
Kallaya Eamlamnam, Suthiluk Patumraj, Naruemon Visedopas, Duangporn Thong-Ngam 
World J Gastroenterol 12(13):2034-2039. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2034
Construction and evaluation of anti-gastrin immunogen based on P64K protein 
Xiang-Hua Xiong, Hong-Liang Zhao, Chong Xue, Wei Zhang, Bing-Fen Yang, Xue-Qin Yao, Zhi-Min Liu 
World J Gastroenterol 12(13):2040-2046. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2040
Effect of Chinese medicine Qinggan Huoxuefang on inducing HSC apoptosis in alcoholic liver fibrosis rats 
Guang Ji, Lei Wang, Shui-Hua Zhang, Jian-Wen Liu, Pei-Yong Zheng, Tao Liu 
World J Gastroenterol 12(13):2047-2052. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2047
Clinical Research
Changes in growth factor and cytokine expression in biliary obstructed rat liver and their relationship with delayed liver regeneration after partial hepatectomy 
Hironobu Makino, Hiroaki Shimizu, Hiroshi Ito, Fumio Kimura, Satoshi Ambiru, Akira Togawa, Masayuki Ohtsuka, Hiroyuki Yoshidome, Atsushi Kato, Hideyuki Yoshitomi, Shigeaki Sawada, Masaru Miyazaki 
World J Gastroenterol 12(13):2053-2059. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2053
Advanced gastrointestinal stromal tumor patients with complete response after treatment with imatinib mesylate 
Kun-Chun Chiang, Tsung-Wen Chen, Chun-Nan Yeh, Feng-Yuan Liu, Hsiang-Lin Lee, Yi-Yin Jan 
World J Gastroenterol 12(13):2060-2064. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2060
Rapid Communication
Oxidative damage, pro-inflammatory cytokines, TGF-α and c-myc in chronic HCV-related hepatitis and cirrhosis 
Fabio Farinati, Romilda Cardin, Marina Bortolami, Maria Guido, Massimo Rugge 
World J Gastroenterol 12(13):2065-2069. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2065
Prevention of de novo HBV infection by the presence of anti-HBs in transplanted patients receiving core antibody-positive livers 
Rafael Barcena, Gloria Moraleda, Javier Moreno, M Dolores Martín, Emilio de Vicente, Jesús Nuño, M Luisa Mateos, Santos del Campo 
World J Gastroenterol 12(13):2070-2074. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2070
Prognosis following transcatheter arterial embolization for 121 patients with unresectable hepatocellular carcinoma with or without a history of treatment 
Atsushi Hiraoka, Teru Kumagi, Masashi Hirooka, Takahide Uehara, Kiyotaka Kurose, Hidehito Iuchi, Yoichi Hiasa, Bunzo Matsuura, Kojiro Michitaka, Seishi Kumano, Hiroaki Tanaka, Yoshimasa Yamashita, Norio Horiike, Teruhito Mochizuki, Morikazu Onji 
World J Gastroenterol 12(13):2075-2079. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2075
Cryptogenic cirrhosis in the region where obesity is not prevalent 
Hideyuki Kojima, Shinya Sakurai, Masahiko Matsumura, Norie Umemoto, Masahito Uemura, Hiroyo Morimoto, Yasuhiro Tamagawa, Hiroshi Fukui 
World J Gastroenterol 12(13):2080-2085. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2080
Safety advantage of endocut mode over endoscopic sphincterotomy for choledocholithiasis 
Hirotada Akiho, Yorinobu Sumida, Kazuya Akahoshi, Atsuhiko Murata, Jiro Ouchi, Yasuaki Motomura, Taisuke Toyomasu, Mitsuhide Kimura, Masaru Kubokawa, Masahiro Matsumoto, Shingo Endo, Kazuhiko Nakamura 
World J Gastroenterol 12(13):2086-2088. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2086
Reduction of virus burden-induced splenectomy in patients with liver cirrhosis related to hepatitis C virus infection 
Tetsuro Sekiguchi, Takeaki Nagamine, Hitoshi Takagi, Masatomo Mori 
World J Gastroenterol 12(13):2089-2094. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2089
Local regulator adrenomedullin contributes to the circulatory disturbance in cirrhotic rats 
Shinya Sakurai, Hideyuki Kojima, Masahito Uemura, Hiroyasu Satoh, Hiroshi Fukui 
World J Gastroenterol 12(13):2095-2102. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2095
Endoprosthesis implantation at the pharyngo-esophageal level: Problems, limitations and challenges 
Efthimios Eleftheriadis, Katerina Kotzampassi 
World J Gastroenterol 12(13):2103-2108. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2103
Circadian variation in expression of G1 phase cyclins D1 and E and cyclin-dependent kinase inhibitors p16 and p21 in human bowel mucosa 
John Griniatsos, Othon P Michail, Stamatios Theocharis, Antonios Arvelakis, Ioannis Papaconstantinou, Evangelos Felekouras, Emmanouel Pikoulis, Ioannis Karavokyros, Chris Bakoyiannis, George Marinos, John Bramis, Panayiotis O Michail 
World J Gastroenterol 12(13):2109-2114. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2109
Portal vein thrombosis: Prevalence, patient characteristics and lifetime risk: A population study based on 23 796 consecutive autopsies 
Mats Ögren, David Bergqvist, Martin Björck, Stefan Acosta, Henry Eriksson, Nils H Sternby 
World J Gastroenterol 12(13):2115-2119. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2115
Effects of hypobaric hypoxia on adenine nucleotide pools, adenine nucleotide transporter activity and protein expression in rat liver 
Cong-Yang Li, Jun-Ze Liu, Li-Ping Wu, Bing Li, Li-Fen Chen 
World J Gastroenterol 12(13):2120-2124. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2120
Case Report
Liver cell adenoma: A case report with clonal analysis and literature review 
Li Gong, Qin Su, Wei Zhang, Ai-Ning Li, Shao-Jun Zhu, Ying-Ming Feng 
World J Gastroenterol 12(13):2125-2129. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2125
Adult intussusception caused by cystic lymphangioma of the colon: A rare case report 
Tae Oh Kim, Jung Hyun Lee, Gwang Ha Kim, Jeong Heo, Dae Hwan Kang, Geun Am Song, Mong Cho 
World J Gastroenterol 12(13):2130-2132. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2130
Spontaneous rupture of splenic hamartoma in a patient with hepatitis C virus-related cirrhosis and portal hypertension: A case report and review of the literature 
Yasuji Seyama, Nobutaka Tanaka, Yoshio Suzuki, Motoki Nagai, Takatoshi Furuya, Yukihiro Nomura, Jimpei Ishii, Masakazu Nobori 
World J Gastroenterol 12(13):2133-2135. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2133
A case of primary biliary cirrhosis complicated by Behçet’s disease and palmoplantar pustulosis 
Haruyo Iwadate, Hiromasa Ohira, Hironobu Saito, Atsushi Takahashi, Tsuyoshi Rai, Junko Takiguchi, Tomomi Sasajima, Hiroko Kobayashi, Hiroshi Watanabe, Yukio Sato 
World J Gastroenterol 12(13):2136-2138. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2136
Chest wall metastasis from unknown primary site of hepatocellular carcinoma 
Yil Sik Hyun, Ho Soon Choi, Joong Ho Bae, Dae Won Jun, Hang Lak Lee, Oh Young Lee, Byung Chul Yoon, Min Ho Lee, Dong Hoo Lee, Choon Shuk Kee, Jung Ho Kang, Moon Hyang Park 
World J Gastroenterol 12(13):2139-2142. Published online Apr 7, 2006. doi: 10.3748/wjg.v12.i13.2139