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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
1
Extracellular vesicles as mediators of vascular inflammation in kidney disease  
Alexandra Helmke, Sibylle von Vietinghoff 
World J Nephrol 5(2):125-138. Published online Mar 6, 2016. doi: 10.5527/wjn.v5.i2.125
2
Role of β2-microglobulin in uremic patients may be greater than originally suspected  
Aysegul Zumrutdal 
World J Nephrol 4(1):98-104. Published online Feb 6, 2015. doi: 10.5527/wjn.v4.i1.98
3
Stop chronic kidney disease progression: Time is approaching  
Usama Abdel Azim Sharaf El Din, Mona Mansour Salem, Dina Ossama Abdulazim 
World J Nephrol 5(3):258-273. Published online May 6, 2016. doi: 10.5527/wjn.v5.i3.258
4
Hepatorenal syndrome: Update on diagnosis and treatment  
Olga Baraldi, Chiara Valentini, Gabriele Donati, Giorgia Comai, Vania Cuna, Irene Capelli, Maria Laura Angelini, Maria Ilaria Moretti, Andrea Angeletti, Fabio Piscaglia, Gaetano La Manna 
World J Nephrol 4(5):511-520. Published online Nov 6, 2015. doi: 10.5527/wjn.v4.i5.511
5
6
Role of different imaging modalities of vascular calcification in predicting outcomes in chronic kidney disease  
Sinee Disthabanchong, Sarinya Boongird 
World J Nephrol 6(3):100-110. Published online May 6, 2017. doi: 10.5527/wjn.v6.i3.100
7
Why do young people with chronic kidney disease die early?  
Shankar Kumar, Richard Bogle, Debasish Banerjee 
World J Nephrol 3(4):143-155. Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.143
8
Tesevatinib ameliorates progression of polycystic kidney disease in rodent models of autosomal recessive polycystic kidney disease  
William E Sweeney, Philip Frost, Ellis D Avner 
World J Nephrol 6(4):188-200. Published online Jul 6, 2017. doi: 10.5527/wjn.v6.i4.188
9
Reclassification of membranoproliferative glomerulonephritis: Identification of a new GN: C3GN  
Maurizio Salvadori, Giuseppina Rosso 
World J Nephrol 5(4):308-320. Published online Jul 6, 2016. doi: 10.5527/wjn.v5.i4.308
10
Pharmacokinetic and pharmacodynamic considerations of antimicrobial drug therapy in cancer patients with kidney dysfunction  
Frieder Keller, Bernd Schröppel, Ulla Ludwig 
World J Nephrol 4(3):330-344. Published online Jul 6, 2015. doi: 10.5527/wjn.v4.i3.330
11
Pathogenesis of glomerular haematuria  
Claudia Yuste, Eduardo Gutierrez, Angel Manuel Sevillano, Alfonso Rubio-Navarro, Juan Manuel Amaro-Villalobos, Alberto Ortiz, Jesus Egido, Manuel Praga, Juan Antonio Moreno 
World J Nephrol 4(2):185-195. Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.185
12
Soy-based renoprotection  
Nancy J McGraw, Elaine S Krul, Elizabeth Grunz-Borgmann, Alan R Parrish 
World J Nephrol 5(3):233-257. Published online May 6, 2016. doi: 10.5527/wjn.v5.i3.233
13
Baroreflex dysfunction in chronic kidney disease  
Manpreet Kaur, Dinu S Chandran, Ashok Kumar Jaryal, Dipankar Bhowmik, Sanjay Kumar Agarwal, Kishore Kumar Deepak 
World J Nephrol 5(1):53-65. Published online Jan 6, 2016. doi: 10.5527/wjn.v5.i1.53
14
Epidemiology, clinical characteristics, and management of chronic kidney disease in human immunodeficiency virus-infected patients  
Minoru Ando, Naoki Yanagisawa 
World J Nephrol 4(3):388-395. Published online Jul 6, 2015. doi: 10.5527/wjn.v4.i3.388
15
Inflammation and nutrition in children with chronic kidney disease  
Juan Tu, Wai W Cheung, Robert H Mak 
World J Nephrol 5(3):274-282. Published online May 6, 2016. doi: 10.5527/wjn.v5.i3.274
16
Treatment of hypogonadotropic male hypogonadism: Case-based scenarios  
Lindsey E Crosnoe-Shipley, Osama O Elkelany, Cyrus D Rahnema, Edward D Kim 
World J Nephrol 4(2):245-253. Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.245
17
Management of nocturnal enuresis - myths and facts  
Rajiv Sinha, Sumantra Raut 
World J Nephrol 5(4):328-338. Published online Jul 6, 2016. doi: 10.5527/wjn.v5.i4.328
18
Nutcracker syndrome  
Kaan Gulleroglu, Basak Gulleroglu, Esra Baskin 
World J Nephrol 3(4):277-281. Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.277
19
Clinicopathological spectrum of snake bite-induced acute kidney injury from India  
Sanjay Vikrant, Ajay Jaryal, Anupam Parashar 
World J Nephrol 6(3):150-161. Published online May 6, 2017. doi: 10.5527/wjn.v6.i3.150
20
Fluid balance concepts in medicine: Principles and practice  
Maria-Eleni Roumelioti, Robert H Glew, Zeid J Khitan, Helbert Rondon-Berrios, Christos P Argyropoulos, Deepak Malhotra, Dominic S Raj, Emmanuel I Agaba, Mark Rohrscheib, Glen H Murata, Joseph I Shapiro, Antonios H Tzamaloukas 
World J Nephrol 7(1):1-28. Published online Jan 6, 2018. doi: 10.5527/wjn.v7.i1.1
21
Renal and perinephric abscesses in West China Hospital: 10-year retrospective-descriptive study  
Xiao-Qin Liu, Cheng-Cheng Wang, Yan-Bin Liu, Kai Liu 
World J Nephrol 5(1):108-114. Published online Jan 6, 2016. doi: 10.5527/wjn.v5.i1.108
22
Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms  
Jeffrey H William, John Danziger 
World J Nephrol 5(2):152-157. Published online Mar 6, 2016. doi: 10.5527/wjn.v5.i2.152
23
Primary and secondary hyperoxaluria: Understanding the enigma  
Bhavna Bhasin, Hatice Melda Ürekli, Mohamed G Atta 
World J Nephrol 4(2):235-244. Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.235
24
Peritoneal dialysis associated infections: An update on diagnosis and management  
Jacob A Akoh 
World J Nephrol 1(4):106-122. Published online Aug 6, 2012. doi: 10.5527/wjn.v1.i4.106
25
Renal dopaminergic system: Pathophysiological implications and clinical perspectives  
Marcelo Roberto Choi, Nicolás Martín Kouyoumdzian, Natalia Lucía Rukavina Mikusic, María Cecilia Kravetz, María Inés Rosón, Martín Rodríguez Fermepin, Belisario Enrique Fernández 
World J Nephrol 4(2):196-212. Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.196
26
Appropriate kidney stone size for ureteroscopic lithotripsy: When to switch to a percutaneous approach  
Ryoji Takazawa, Sachi Kitayama, Toshihiko Tsujii 
World J Nephrol 4(1):111-117. Published online Feb 6, 2015. doi: 10.5527/wjn.v4.i1.111
27
Nephropathy in dietary hyperoxaluria: A potentially preventable acute or chronic kidney disease  
Robert H Glew, Yijuan Sun, Bruce L Horowitz, Konstantin N Konstantinov, Marc Barry, Joanna R Fair, Larry Massie, Antonios H Tzamaloukas 
World J Nephrol 3(4):122-142. Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.122
28
Application of established pathophysiologic processes brings greater clarity to diagnosis and treatment of hyponatremia  
John K Maesaka, Louis J Imbriano, Nobuyuki Miyawaki 
World J Nephrol 6(2):59-71. Published online Mar 6, 2017. doi: 10.5527/wjn.v6.i2.59
29
30
Chronic kidney disease and erectile dysfunction  
Etsu Suzuki, Hiroaki Nishimatsu, Shigeyoshi Oba, Masao Takahashi, Yukio Homma 
World J Nephrol 3(4):220-229. Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.220
31
Bacteremia in hemodialysis patients  
Masashi Suzuki, Nobuhiko Satoh, Motonobu Nakamura, Shoko Horita, George Seki, Kyoji Moriya 
World J Nephrol 5(6):489-496. Published online Nov 6, 2016. doi: 10.5527/wjn.v5.i6.489
32
Update on immunoglobulin A nephropathy, Part I: Pathophysiology  
Maurizio Salvadori, Giuseppina Rosso 
World J Nephrol 4(4):455-467. Published online Sep 6, 2015. doi: 10.5527/wjn.v4.i4.455
33
Preeclampsia from a renal point of view: Insides into disease models, biomarkers and therapy  
Janina Müller-Deile, Mario Schiffer 
World J Nephrol 3(4):169-181. Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.169
34
Combined functional and anatomical diagnostic endpoints for assessing arteriovenous fistula dysfunction  
Ehsan Rajabi-Jaghargh, Rupak K Banerjee 
World J Nephrol 4(1):6-18. Published online Feb 6, 2015. doi: 10.5527/wjn.v4.i1.6
35
Renin-angiotensin system in the kidney: What is new?  
Fernanda M Ferrão, Lucienne S Lara, Jennifer Lowe 
World J Nephrol 3(3):64-76. Published online Aug 6, 2014. doi: 10.5527/wjn.v3.i3.64
36
Diabetes mellitus increases the prevalence of anemia in patients with chronic kidney disease: A nested case-control study  
Charalampos Loutradis, Alexandra Skodra, Panagiotis Georgianos, Panagiota Tolika, Dimitris Alexandrou, Afroditi Avdelidou, Pantelis A Sarafidis 
World J Nephrol 5(4):358-366. Published online Jul 6, 2016. doi: 10.5527/wjn.v5.i4.358
37
Constitutive renal Rel/nuclear factor-κB expression in Lewis polycystic kidney disease rats  
Michelle H T Ta, Kristina G Schwensen, David Liuwantara, David L Huso, Terry Watnick, Gopala K Rangan 
World J Nephrol 5(4):339-357. Published online Jul 6, 2016. doi: 10.5527/wjn.v5.i4.339
38
Hypertonicity: Clinical entities, manifestations and treatment  
Helbert Rondon-Berrios, Christos Argyropoulos, Todd S Ing, Dominic S Raj, Deepak Malhotra, Emmanuel I Agaba, Mark Rohrscheib, Zeid J Khitan, Glen H Murata, Joseph I Shapiro, Antonios H Tzamaloukas 
World J Nephrol 6(1):1-13. Published online Jan 6, 2017. doi: 10.5527/wjn.v6.i1.1
39
Use of percutaneous nephrostomy and ureteral stenting in management of ureteral obstruction  
Linda Hsu, Hanhan Li, Daniel Pucheril, Moritz Hansen, Raymond Littleton, James Peabody, Jesse Sammon 
World J Nephrol 5(2):172-181. Published online Mar 6, 2016. doi: 10.5527/wjn.v5.i2.172
40
Biomarkers in chronic kidney disease, from kidney function to kidney damage  
Salvador Lopez-Giacoman, Magdalena Madero 
World J Nephrol 4(1):57-73. Published online Feb 6, 2015. doi: 10.5527/wjn.v4.i1.57
41
42
Causal relationship between hypoalbuminemia and acute kidney injury  
Christian J Wiedermann, Wolfgang Wiedermann, Michael Joannidis 
World J Nephrol 6(4):176-187. Published online Jul 6, 2017. doi: 10.5527/wjn.v6.i4.176
43
Vascular calcification: When should we interfere in chronic kidney disease patients and how?  
Usama Abdel Azim Sharaf El Din, Mona Mansour Salem, Dina Ossama Abdulazim 
World J Nephrol 5(5):398-417. Published online Sep 6, 2016. doi: 10.5527/wjn.v5.i5.398
44
Complement involvement in kidney diseases: From physiopathology to therapeutical targeting  
Maurizio Salvadori, Giuseppina Rosso, Elisabetta Bertoni 
World J Nephrol 4(2):169-184. Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.169
45
Update on hemolytic uremic syndrome: Diagnostic and therapeutic recommendations  
Maurizio Salvadori, Elisabetta Bertoni 
World J Nephrol 2(3):56-76. Published online Aug 6, 2013. doi: 10.5527/wjn.v2.i3.56
46
Role of calcium in polycystic kidney disease: From signaling to pathology  
Alessandra Mangolini, Lucia de Stephanis, Gianluca Aguiari 
World J Nephrol 5(1):76-83. Published online Jan 6, 2016. doi: 10.5527/wjn.v5.i1.76
47
Secondary amyloidosis in autoinflammatory diseases and the role of inflammation in renal damage  
Roberto Scarpioni, Marco Ricardi, Vittorio Albertazzi 
World J Nephrol 5(1):66-75. Published online Jan 6, 2016. doi: 10.5527/wjn.v5.i1.66
48
What is the optimal level of vitamin D in non-dialysis chronic kidney disease population?  
Pablo Molina, José L Górriz, Mariola D Molina, Sandra Beltrán, Belén Vizcaíno, Verónica Escudero, Julia Kanter, Ana I Ávila, Jordi Bover, Elvira Fernández, Javier Nieto, Secundino Cigarrán, Enrique Gruss, Gema Fernández-Juárez, Alberto Martínez-Castelao, Juan F Navarro-González, Ramón Romero, Luis M Pallardó 
World J Nephrol 5(5):471-481. Published online Sep 6, 2016. doi: 10.5527/wjn.v5.i5.471
49
Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus  
Junichi Fujii, Toshihiro Kurahashi, Tasuku Konno, Takujiro Homma, Yoshihito Iuchi 
World J Nephrol 4(2):213-222. Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.213
50
Obesity in kidney disease: A heavyweight opponent  
Raphael Jose Ferreira Felizardo, Marina Burgos da Silva, Cristhiane Favero Aguiar, Niels Olsen Saraiva Câmara 
World J Nephrol 3(3):50-63. Published online Aug 6, 2014. doi: 10.5527/wjn.v3.i3.50