Published online Feb 6, 2015. doi: 10.5527/wjn.v4.i1.57
Peer-review started: July 30, 2014
First decision: September 16, 2014
Revised: October 28, 2014
Accepted: November 7, 2014
Article in press: November 10, 2014
Published online: February 6, 2015
Core tip: Until more accurate equations are developed the chronic kidney disease (CKD) epidemiology collaboration appears to be superior to other glomerular filtration rate (GFR) estimating equations. In circumstances where CKD requires confirmation estimated GFR based on the combined creatinine-cystatin C equation is recommended. The recent advances in molecular biology have resulted in promising biomarkers for CKD detection and prognosis; however more research is needed before applying them into clinical practice.