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Editorial
A candidate targeting molecule of insulin-like growth factor-I receptor for gastrointestinal cancers 
Yasushi Adachi, Hiroyuki Yamamoto, Hirokazu Ohashi, Takao Endo, David P Carbone, Kohzoh Imai, Yasuhisa Shinomura 
World J Gastroenterol 16(46):5779-5789. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5779
Pathobiology of the neutrophil-intestinal epithelial cell interaction: Role in carcinogenesis 
Paul M Hofman 
World J Gastroenterol 16(46):5790-5800. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5790
Topic Highlight
Leptin in hepatocellular carcinoma 
Shen-Nien Wang, King Teh Lee, Chen-Guo Ker 
World J Gastroenterol 16(46):5801-5809. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5801
Observation
Reproductive changes associated with celiac disease 
Hugh James Freeman 
World J Gastroenterol 16(46):5810-5814. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5810
Original Article
Toll-like receptor 9 gene mutations and polymorphisms in Japanese ulcerative colitis patients 
Kaori Fuse, Kyoko Katakura, Natsumi Sakamoto, Hiromasa Ohira 
World J Gastroenterol 16(46):5815-5821. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5815
Retrorectal tumors in adults: Magnetic resonance imaging findings 
Bo-Lin Yang, Yun-Fei Gu, Wan-Jin Shao, Hong-Jin Chen, Gui-Dong Sun, Hei-Ying Jin, Xin Zhu 
World J Gastroenterol 16(46):5822-5829. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5822
Brief Article
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases 
Johannes W Rey, Andrea Noetel, Aline Hardt, Ali Canbay, Hakan Alakus, Axel zur Hausen, Hans Peter Dienes, Uta Drebber, Margarete Odenthal 
World J Gastroenterol 16(46):5830-5837. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5830
Translation and validation of the Greek chronic liver disease questionnaire 
Zoi Kollia, Evridiki Patelarou, Victoria Vivilaki, Eleni Kollia, Florentia Kefou, Ioannis Elefsiniotis, Spyros P Dourakis, Hero Brokalaki 
World J Gastroenterol 16(46):5838-5844. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5838
Serum immune-activation potency and response to anti-TNF-α therapy in Crohn's disease 
Hanne Rintamäki, Taina Sipponen, Harri M Salo, Outi Vaarala, Kaija-Leena Kolho 
World J Gastroenterol 16(46):5845-5851. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5845
Nitric oxide activation of a potassium channel (BKCa) in feline lower esophageal sphincter 
Marie-Claude L’Heureux, Ahmad Muinuddin, Herbert Y Gaisano, Nicholas E Diamant 
World J Gastroenterol 16(46):5852-5860. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5852
Effects of meal size and proximal-distal segmentation on gastric activity 
Madileine F Américo, Marjorie V Ietsugu, Fernando G Romeiro, Luciana A Corá, Ricardo B Oliveira, José Ricardo A Miranda 
World J Gastroenterol 16(46):5861-5868. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5861
PPIs are not associated with a lower incidence of portal-hypertension-related bleeding in cirrhosis 
Mauricio Garcia-Saenz-de-Sicilia, Francisco Sanchez-Avila, Norberto C Chavez-Tapia, Gustavo Lopez-Arce, Sandra Garcia-Osogobio, Roberto Ruiz-Cordero, Felix I Tellez-Avila 
World J Gastroenterol 16(46):5869-5873. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5869
Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry 
Jin-Lian Chen, Hui-Qing Tang, Jun-Duo Hu, Jing Fan, Jing Hong, Jian-Zhong Gu 
World J Gastroenterol 16(46):5874-5880. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5874
Impact of KRAS mutation and PTEN expression on cetuximab-treated colorectal cancer 
Fang-Hua Li, Lin Shen, Zhuang-Hua Li, Hui-Yan Luo, Miao-Zhen Qiu, Hui-Zhong Zhang, Yu-Hong Li, Rui-Hua Xu 
World J Gastroenterol 16(46):5881-5888. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5881
Irinotecan-involved regimens for advanced gastric cancer: A pooled-analysis of clinical trials 
Dan-Ling Wang, Dong-Ying Gu, Hua-Ying Huang, Zhi Xu, Jin-Fei Chen 
World J Gastroenterol 16(46):5889-5894. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5889
Hepatic blood inflow occlusion without hemihepatic artery control in treatment of hepatocellular carcinoma 
Shan Jin, Chao-Liu Dai 
World J Gastroenterol 16(46):5895-5900. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5895
Human papillomavirus DNA and P16INK4A expression in concurrent esophageal and gastric cardia cancers 
Guang-Cheng Ding, Jing-Li Ren, Fu-Bao Chang, Ji-Lin Li, Ling Yuan, Xin Song, Sheng-Li Zhou, Tao Guo, Zong-Min Fan, Yi Zeng, Li-Dong Wang 
World J Gastroenterol 16(46):5901-5906. Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5901