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Open-Access Journal
Editorial
Adjuvant treatment in biliary tract cancer: To treat or not to treat? 
Stefano Cereda, Carmen Belli, Michele Reni 
World J Gastroenterol 18(21):2591-2596. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2591
Field of Vision
Motor vehicle accidents: How should cirrhotic patients be managed? 
Takumi Kawaguchi, Eitaro Taniguchi, Michio Sata 
World J Gastroenterol 18(21):2597-2599. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2597
Topic Highlight
Pregnancy related issues in inflammatory bowel disease: Evidence base and patients' perspective 
Christian P Selinger, Rupert WL Leong, Simon Lal 
World J Gastroenterol 18(21):2600-2608. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2600
Review
Leaky gut and the liver: A role for bacterial translocation in nonalcoholic steatohepatitis 
Yaron Ilan 
World J Gastroenterol 18(21):2609-2618. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2609
Original Article
Juvenile ferric iron prevents microbiota dysbiosis and colitis in adult rodents 
Chourouk Ettreiki, Pascale Gadonna-Widehem, Irène Mangin, Moïse Coëffier, Carine Delayre-Orthez, Pauline M Anton 
World J Gastroenterol 18(21):2619-2629. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2619
High dose glargine alters the expression profiles of microRNAs in pancreatic cancer cells 
Wei-Guang Li, Yao-Zong Yuan, Min-Min Qiao, Yong-Ping Zhang 
World J Gastroenterol 18(21):2630-2639. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2630
Suppression of colorectal cancer metastasis by nigericin through inhibition of epithelial-mesenchymal transition 
Hou-Min Zhou, Tao-Tao Dong, Lin-Lin Wang, Bo Feng, Hong-Chao Zhao, Xiu-Ke Fan, Min-Hua Zheng 
World J Gastroenterol 18(21):2640-2648. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2640
Brief Article
Association between autoimmune pancreatitis and systemic autoimmune diseases 
Viktória Terzin, Imre Földesi, László Kovács, Gyula Pokorny, Tibor Wittmann, László Czakó 
World J Gastroenterol 18(21):2649-2653. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2649
Clinical course of sub-centimeter-sized nodules detected during surveillance for hepatocellular carcinoma 
Yang Won Min, Geum-Youn Gwak, Min Woo Lee, Moon Seok Choi, Joon Hyoek Lee, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo 
World J Gastroenterol 18(21):2654-2660. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2654
Family history influences the early onset of hepatocellular carcinoma 
Chung-Hwa Park, Seung-Hee Jeong, Hyeon-Woo Yim, Jin Dong Kim, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon 
World J Gastroenterol 18(21):2661-2667. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2661
Risk modification of colorectal cancer susceptibility by interleukin-8 -251T>A polymorphism in Malaysians 
Mohd Aminudin Mustapha, Siti Nurfatimah Mohd Shahpudin, Ahmad Aizat Abdul Aziz, Ravindran Ankathil 
World J Gastroenterol 18(21):2668-2673. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2668
Eradication of Helicobacter pylori increases childhood growth and serum acylated ghrelin levels 
Yao-Jong Yang, Bor-Shyang Sheu, Hsiao-Bai Yang, Cheng-Chan Lu, Ching-Chun Chuang 
World J Gastroenterol 18(21):2674-2681. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2674
Colorectal cancer screening: Comparison of transferrin and immuno fecal occult blood test 
Ji-Gui Chen, Juan Cai, Huan-Lei Wu, Hua Xu, Yu-Xing Zhang, Chao Chen, Qian Wang, Jun Xu, Xiang-Lin Yuan 
World J Gastroenterol 18(21):2682-2688. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2682
Health-related quality of life evaluated by tumor node metastasis staging system in patients with hepatocellular carcinoma 
Cui-Xia Qiao, Xiao-Feng Zhai, Chang-Quan Ling, Qing-Bo Lang, Hui-Juan Dong, Qun Liu, Mou-Duo Li 
World J Gastroenterol 18(21):2689-2694. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2689
Effect of intensive vs conventional insulin therapy on perioperative nutritional substrates metabolism in patients undergoing gastrectomy 
Han-Cheng Liu, Yan-Bing Zhou, Dong Chen, Zhao-Jian Niu, Yang Yu 
World J Gastroenterol 18(21):2695-2703. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2695
GABA stimulates human hepatocellular carcinoma growth through overexpressed GABAA receptor theta subunit 
Yue-Hui Li, Yan Liu, Yan-Dong Li, Yan-Hong Liu, Feng Li, Qiang Ju, Ping-Li Xie, Guan-Cheng Li 
World J Gastroenterol 18(21):2704-2711. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2704
Phosphatase and tensin homolog expression related to cetuximab effects in colorectal cancer patients: A meta-analysis 
Yue Shen, Jian Yang, Zhi Xu, Dong-Ying Gu, Jin-Fei Chen 
World J Gastroenterol 18(21):2712-2718. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2712
Aberrant methylation and downregulation of sall3 in human hepatocellular carcinoma 
Xue-Xi Yang, Jing-Zhe Sun, Fen-Xia Li, Ying-Song Wu, Hong-Yan Du, Wei Zhu, Xiang-Hong Li, Ming Li 
World J Gastroenterol 18(21):2719-2726. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2719
Case Report
A pediatric non-protein losing Menetrier's disease successfully treated with octreotide long acting release 
Giovanni Di Nardo, Salvatore Oliva, Marina Aloi, Federica Ferrari, Simone Frediani, Adriana Marcheggiano, Salvatore Cucchiara 
World J Gastroenterol 18(21):2727-2729. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2727
Infliximab stopped severe gastrointestinal bleeding in Crohn's disease 
Satimai Aniwan, Surasak Eakpongpaisit, Boonlert Imraporn, Surachai Amornsawadwatana, Rungsun Rerknimitr 
World J Gastroenterol 18(21):2730-2734. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2730
Letters To The Editor
Dual therapy for third-line Helicobacter pylori eradication and urea breath test prediction 
Toshihiro Nishizawa, Hidekazu Suzuki, Takama Maekawa, Naohiko Harada, Tatsuya Toyokawa, Toshio Kuwai, Masanori Ohara, Takahiro Suzuki, Masahiro Kawanishi, Kenji Noguchi, Toshiyuki Yoshio, Shinji Katsushima, Hideo Tsuruta, Eiji Masuda, Munehiro Tanaka, Shunsuke Katayama, Norio Kawamura, Yuko Nishizawa, Toshifumi Hibi, Masahiko Takahashi 
World J Gastroenterol 18(21):2735-2738. Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2735