Health-related quality of life evaluated by tumor node metastasis staging system in patients with hepatocellular carcinoma

doi:10.3748/wjg.v18.i21.2689

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Jun 7, 2012 (publication date) through Apr 19, 2024

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Times Cited (27)

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2012; 18(21): 2689-2694
Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2689

Table 1 Patient characteristics n (%)

Factors		P value
Age (yr), median (range)	52 (28–75)	0.3509
Sex		< 0.001
Male	133 (95.0)
Female	7 (5.0)
Level of education		< 0.0001
Primary school	20 (14.0)
Secondary school	56 (40.0)
Commercial or vocational school	64 (46.0)
Tumor, node, metastasis stage
I	49 (35.0)	0.0023
II	35 (25.0)
IIIA	29 (20.7)
IIIB	27(19.3)
IIIC	0
IV	0
Etiology
Hepatitis B	135 (96.5)
Hepatitis C	2 (1.4)
Alcoholic	2 (1.4)
Cryptogenic	1 (0.7)
Child-Pugh class
A	84 (60.0)
B	29 (20.7)
C	27 (19.3)

Table 2 Functional assessment of cancer therapy-hepatobiliary mean scores (n =140)

FACT-Hep subscales	mean ± SD	Sum of scores	F	P value
PWB	16.47 ± 4.27	276.86	16.99	0.000
SFWB	14.52 ± 3.35	37.08	1.71	0.184
EWB	12.74 ± 3.39	131.33	7.11	0.001
FWB	17.57 ± 3.93	165.32	5.84	0.004
HepCS	41.46 ± 9.52	754.79	5.72	0.004

PWB: Physical well-being; SFWB: Social and family well-being; EWB: Emotional well-being; FWB: Functional well-being; HepCS: Hepatobiliary cancer subscale; FACT-Hep: Functional assessment of cancer therapy-hepatobiliary.

Table 3 Functional assessment of cancer therapy-hepatobiliary subscale results by tumor node metastasis stage of hepatocellular carcinoma and by Child-Pugh class (mean ± SD)

	n	PWB	SFWB	EWB	FWB	HepCS
TNM stage
I	49	21 ± 2.15^d^f	15.81 ± 3.68	15.11 ± 2.79^d^f	19.96 ± 3.20^d^f	48.52 ± 8.36^d^f
II	35	19.07 ± 3.41^b^f	14.69 ± 2.82	13.38 ± 3.01^b	19.24 ± 2.21^b	45.45 ± 10.01^b
IIIA	29	16.29 ± 2.24^b^d	14.66 ± 3.3	13.06 ± 3.08^b	18.37 ± 3.98^b	41.29 ± 7.05^b
IIIB	27	12.41 ± 2.88^b^d^f	13.61 ± 3.32^a	10.84 ± 3.15^b^d^f	14.69 ± 3.39^b^d	35.35 ± 7.44^b^d
Child-Pugh class
A	73	19.56 ± 2.79	15.29 ± 3.34	14.12 ± 2.89	19.58 ± 3.26^j	46.12 ± 8.79^j
B	40	16.65 ± 2.79^h	14.25 ± 3.08	11.8 ± 3.05	16.48 ± 2.98^h	38.88 ± 6.61^h
C	27	10.52 ± 2.41^h	12.85 ± 3.21^h	10.41 ± 3.49^h^j	13.78 ± 3.48^h^j	32.7 ± 7.38^h^j

^aP < 0.05,

^bP < 0.01 vs Stage I;

^dP < 0.01 vs Stage II;

^fP < 0.01 vs Stage IIIA;

^hP < 0.01 vs Child A;

^jP < 0.01 vs Child B. PWB: Physical well-being; SFWB: Social and family well-being; EWB: Emotional well-being; FWB: Functional well-being; HepCS: Hepatobiliary cancer subscale.

Citation: Qiao CX, Zhai XF, Ling CQ, Lang QB, Dong HJ, Liu Q, Li MD. Health-related quality of life evaluated by tumor node metastasis staging system in patients with hepatocellular carcinoma. World J Gastroenterol 2012; 18(21): 2689-2694
URL: https://www.wjgnet.com/1007-9327/full/v18/i21/2689.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i21.2689