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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
1
Molecular pathogenesis of glioblastoma multiforme: Nuances, obstacles, and implications for treatment  
Siddharth K Joshi, Nevena Lucic, Richard Zuniga 
World J Neurol 5(3):88-101. Published online Sep 28, 2015. doi: 10.5316/wjn.v5.i3.88
2
Targeting remyelination treatment for multiple sclerosis  
Maheen Nadeem, Lindsay Sklover, Jacob A Sloane 
World J Neurol 5(1):5-16. Published online Mar 28, 2015. doi: 10.5316/wjn.v5.i1.5
3
Clinical consequences of centipede bite: Is it neurotoxic?  
Ioannis N Mavridis, Maria Meliou, Efstratios-Stylianos Pyrgelis 
World J Neurol 6(2):23-29. Published online Jun 28, 2016. doi: 10.5316/wjn.v6.i2.23
4
Cerebral ageing-the role of insulin and insulin-like growth factor signalling: A review  
Georgia Romain, Jolanta Opacka-Juffry 
World J Neurol 4(3):12-22. Published online Sep 28, 2014. doi: 10.5316/wjn.v4.i3.12
5
Protein seeding in Alzheimer’s disease and Parkinson’s disease: Similarities and differences  
Tarek Ibrahim, JoAnne McLaurin 
World J Neurol 4(4):23-35. Published online Dec 28, 2014. doi: 10.5316/wjn.v4.i4.23
6
Disciplined sleep for healthy living: Role of noradrenaline  
Rachna Mehta, Abhishek Singh, Birendra Nath Mallick 
World J Neurol 7(1):6-23. Published online Mar 28, 2017. doi: 10.5316/wjn.v7.i1.6
7
Rituximab in neuromyelitis optica: A review of literature  
Ericka Wong, Vijay A Vishwanath, Ilya Kister 
World J Neurol 5(1):39-46. Published online Mar 28, 2015. doi: 10.5316/wjn.v5.i1.39
8
9
Pure motor stroke as the most frequent lacunar syndrome: A clinical update  
Adrià Arboix, María José Sánchez, Josep Lluís Martí-Vilalta 
World J Neurol 3(4):129-132. Published online Dec 28, 2013. doi: 10.5316/wjn.v3.i4.129
10
Medicine in the future - with subspecialists in medullary neurology and brain dentistry  
J Howard Jaster 
World J Neurol 5(4):107-112. Published online Dec 28, 2015. doi: 10.5316/wjn.v5.i4.107
11
Thrombolysis for mild stroke  
Hai-Chao Ji, Le-Tian Yang, Fu-Ling Yan 
World J Neurol 5(2):57-63. Published online Jun 28, 2015. doi: 10.5316/wjn.v5.i2.57
12
13
Coenzyme Q10 in neurodegenerative disorders: Potential benefit of CoQ10 supplementation for multiple system atrophy  
Hiroshi Takahashi, Kotaro Shimoda 
World J Neurol 4(1):1-6. Published online Mar 28, 2014. doi: 10.5316/wjn.v4.i1.1
14
Periodontal surgery in a stage II Parkinson’s disease patient: Report of a case with special considerations  
Ritika Arora, R K Sharma, Shikha Tewari, Himanshu Kapoor 
World J Neurol 7(2):24-27. Published online Jun 28, 2017. doi: 10.5316/wjn.v7.i2.24
15
Overview of botulinum toxin as a treatment for spasticity in stroke patients  
Hirotaka Isoyama, Naoyuki Takeuchi 
World J Neurol 3(4):133-137. Published online Dec 28, 2013. doi: 10.5316/wjn.v3.i4.133
16
Molecular diagnosis of autosomal recessive cerebellar ataxia in the whole exome/genome sequencing era  
Christina Votsi, Kyproula Christodoulou 
World J Neurol 3(4):115-128. Published online Dec 28, 2013. doi: 10.5316/wjn.v3.i4.115
17
Drinking during pregnancy: Potential role of endocannabinoid signaling in fetal alcohol effects  
Basalingappa L Hungund 
World J Neurol 7(1):1-5. Published online Mar 28, 2017. doi: 10.5316/wjn.v7.i1.1
18
Advances in the molecular diagnosis of Charcot-Marie-Tooth disease  
Paschalis Nicolaou, Kyproula Christodoulou 
World J Neurol 3(3):42-55. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.42
19
Variation in experimental autoimmune encephalomyelitis scores in a mouse model of multiple sclerosis  
Chisen Takeuchi, Kanato Yamagata, Takako Takemiya 
World J Neurol 3(3):56-61. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.56
20
Mavridis’ atrophy in Parkinson’s disease-five years later: Future perspectives  
Ioannis N Mavridis, Efstratios-Stylianos Pyrgelis 
World J Neurol 5(1):1-4. Published online Mar 28, 2015. doi: 10.5316/wjn.v5.i1.1
21
Prevalence, clinical features and treatment of depression in Parkinson’s disease: An update  
Omar ME Abdel-Salam 
World J Neurol 5(1):17-38. Published online Mar 28, 2015. doi: 10.5316/wjn.v5.i1.17
22
Predictors of future stroke in adults 60-64 years living in the community  
Nicolas Cherbuin, Leeanne Carey, Moyra Mortby, Kaarin J Anstey 
World J Neurol 6(1):14-22. Published online Mar 28, 2016. doi: 10.5316/wjn.v6.i1.14
23
Secondary prevention of ischaemic stroke  
Irene Volonghi, Alessandro Padovani, Elisabetta Del Zotto, Alessia Giossi, Paolo Costa, Andrea Morotti, Loris Poli, Alessandro Pezzini 
World J Neurol 3(4):97-114. Published online Dec 28, 2013. doi: 10.5316/wjn.v3.i4.97
24
Involvement of leak K+ channels in neurological disorders  
Hiroki Toyoda 
World J Neurol 5(1):52-56. Published online Mar 28, 2015. doi: 10.5316/wjn.v5.i1.52
25
26
Neuritin: A therapeutic candidate for promoting axonal regeneration  
Tadayuki Shimada, Hiroko Sugiura, Kanato Yamagata 
World J Neurol 3(4):138-143. Published online Dec 28, 2013. doi: 10.5316/wjn.v3.i4.138
27
Resolution of idiopathic intracranial hypertension after sustained lowering of cerebrospinal fluid pressure  
Peter C Gates 
World J Neurol 5(1):47-51. Published online Mar 28, 2015. doi: 10.5316/wjn.v5.i1.47
28
Human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis: Clinical presentation and pathophysiology  
Jean-Pierre Louboutin 
World J Neurol 5(3):68-73. Published online Sep 28, 2015. doi: 10.5316/wjn.v5.i3.68
29
Relevance of long QT syndrome in clinical neurology  
Marcus M Unger, Klaus Fassbender 
World J Neurol 3(3):25-28. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.25
30
Challenge of the translational neuroscience  
Rodrigo Ramos-Zúñiga 
World J Neurol 5(4):102-106. Published online Dec 28, 2015. doi: 10.5316/wjn.v5.i4.102
31
Time windows for postnatal changes in morphology and membrane excitability of genioglossal and oculomotor motoneurons  
Livia Carrascal, JoséLuis Nieto-González, Ricardo Pardillo-Díaz, Rosario Pásaro, Germán Barrionuevo, Blas Torres, William E Cameron, Pedro Núñez-Abades 
World J Neurol 5(4):113-131. Published online Dec 28, 2015. doi: 10.5316/wjn.v5.i4.113
32
33
Hypertensive brain stem encephalopathy with pontine hemorrhage: A case report  
Zhong-He Zhou, Fang Qu, Hui-Sheng Chen 
World J Neurol 3(3):83-86. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.83
34
Low grade spinal malignant triton tumor with mature skeletal muscle differentiation  
Ming Zhang, Michael Weaver, Jasvir S Khurana, Abir L Mukherjee 
World J Neurol 3(3):75-78. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.75
35
Cannabinoids: Do they have the potential to treat the symptoms of multiple sclerosis?  
Zubair Ahmed 
World J Neurol 3(4):87-96. Published online Dec 28, 2013. doi: 10.5316/wjn.v3.i4.87
36
Thickness-based correlations of cortical areas involved in senses, speech and cognitive processes  
Ioannis Mavridis, Konstantinos Lontos, Sophia Anagnostopoulou 
World J Neurol 3(3):67-74. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.67
37
Hashimoto’s encephalopathy presenting as acute cognitive decline in an elderly male  
Madan Raj Aryal, Smith Giri, Naba Raj Mainali, Karen Smith 
World J Neurol 3(1):1-3. Published online Mar 28, 2013. doi: 10.5316/wjn.v3.i1.1
38
Atypical neurological symptoms associated with CGG expansions of the FMR1 gene  
Esteban Peña, Marcos Llanero 
World J Neurol 3(4):148-151. Published online Dec 28, 2013. doi: 10.5316/wjn.v3.i4.148
39
Variation in risk factors of dementia among four elderly patient cohorts  
Baqar Husaini, Van Cain, Meggan Novotny, Zahid Samad, Robert Levine, Majaz Moonis 
World J Neurol 4(2):7-11. Published online Jun 28, 2014. doi: 10.5316/wjn.v4.i2.7
40
A common genetic mechanism underlying susceptibility to posttraumatic stress disorder  
Zhen He, Li Cui, Bei He, Sherry A Ferguson, Merle G Paule 
World J Neurol 3(3):14-24. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.14
41
Antiplatelet strategy for acute ischemic stroke: A mini review  
Zhong-He Zhou, Hui-Sheng Chen 
World J Neurol 3(4):144-147. Published online Dec 28, 2013. doi: 10.5316/wjn.v3.i4.144
42
Complete recovery of severe tetraparesis after excision of large C1-osteochondroma  
Essam A Elgamal 
World J Neurol 3(3):79-82. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.79
43
Depression in adults with epilepsy: Relationship to psychobiological variables  
Sherifa Ahmad Hamed, Nabil Abdel-Hakim Metwaly, Mahmoud Mohamad Hassan, Khalid Ahmad Mohamed, Mohamad Abdel-Rahman Ahmad, Ahmad Abdel-Magid Soliman, Abdel-Rahman Mohamed Elsaied 
World J Neurol 2(1):1-10. Published online Feb 28, 2012. doi: 10.5316/wjn.v2.i1.1
44
What is the purpose of launching World Journal of Neurology?  
Vincenzo Solfrizzi 
World J Neurol 1(1):1-3. Published online Dec 28, 2011. doi: 10.5316/wjn.v1.i1.1
45
Anterior communicating artery aneurysm associated with duplicated hypoplastic right A1 segment  
Ioannis N Mavridis, Sophia Anagnostopoulou 
World J Neurol 3(2):10-13. Published online Jun 28, 2013. doi: 10.5316/wjn.v3.i2.10
46
Human obturator nerve: Gross anatomy  
Sophia Anagnostopoulou, Ioannis Mavridis 
World J Neurol 3(3):62-66. Published online Sep 28, 2013. doi: 10.5316/wjn.v3.i3.62
47
Nucleus accumbens stereotactic surgery: Achieving accuracy through area M  
Ioannis N Mavridis 
World J Neurol 3(2):7-9. Published online Jun 28, 2013. doi: 10.5316/wjn.v3.i2.7
48
Anatomizing the “King of Neurosciences”  
Ioannis N Mavridis 
World J Neurol 3(2):4-6. Published online Jun 28, 2013. doi: 10.5316/wjn.v3.i2.4