Published online Jun 28, 2016. doi: 10.5316/wjn.v6.i2.23
Peer-review started: March 17, 2016
First decision: April 19, 2016
Revised: April 28, 2016
Accepted: May 31, 2016
Article in press: June 2, 2016
Published online: June 28, 2016
Core tip: Centipede bite commonly causes only local reactions, which usually resolve within a few days without sequelae. The patients in the majority of cases describe a painful but benign syndrome. Mild constitutional symptoms are relatively frequent, whereas severe systematic reactions, such as anaphylaxis, hypotension and even myocardial ischemia, are rare. According to the current literature, the centipede bite does not seem to be neurotoxic to humans. However, it commonly causes symptoms mediated by the nervous system. These include local and generalized symptoms, with the first dominated by sensory disturbances and the second by non-specific symptoms such as headache, anxiety and vagotonia.