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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Possible convulsion and electroencephalographic abnormality in a patient taking long-term oral clarithromycin: A case report
Wataru Shiraishi, Department of Neurology, Kokura Memorial Hospital, Kitakyushu 802-8555, Fukuoka, Japan
Author contributions: Shiraishi W contributed to data collection, writing, and editing of the manuscript.
Informed consent statement: Informed consent was obtained from the patient for publication of this case.
Conflict-of-interest statement: All the authors declare no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wataru Shiraishi, MD, PhD, Deputy Director, Doctor, Department of Neurology, Kokura Memorial Hospital, 3-2-1 Asano, Kokurakita-ku, Kitakyushu 802-8555, Fukuoka, Japan. whitestone_db5@yahoo.co.jp
Received: September 10, 2022
Peer-review started: September 10, 2022
First decision: October 24, 2022
Revised: October 25, 2022
Accepted: October 31, 2022
Article in press: October 31, 2022
Published online: November 15, 2022
Peer-review started: September 10, 2022
First decision: October 24, 2022
Revised: October 25, 2022
Accepted: October 31, 2022
Article in press: October 31, 2022
Published online: November 15, 2022
Core Tip
Core Tip: Clarithromycin is a frequently used medication and has a long history of use. The rarity of reports of convulsions induced by clarithromycin suggests that the induction of convulsions by clarithromycin is a rare phenomenon or has been overlooked. Clarithromycin is a frequently prescribed drug but has many interactions. Therefore, we report this case as a cautionary statement for all neurologists. Also, the measurement of QT time may be a valuable method of assessing clarithromycin excess.