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Editorial
Interaction of major genes predisposing to hepatocellular carcinoma with genes encoding signal transduction pathways influences tumor phenotype and prognosis 
Francesco Feo, Maddalena Frau, Rosa Maria Pascale 
World J Gastroenterol 14(43):6601-6615. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6601
Renal elimination of organic anions in cholestasis 
Adriana Mónica Torres 
World J Gastroenterol 14(43):6616-6621. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6616
Diagnosis and clinical implications of pancreatobiliary reflux 
Terumi Kamisawa, Hajime Anjiki, Naoto Egawa, Masanao Kurata, Goro Honda, Kouji Tsuruta 
World J Gastroenterol 14(43):6622-6626. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6622
Review
Is pegylated interferon superior to interferon, with ribavarin, in chronic hepatitis C genotypes 2/3? 
Ijaz S Jamall, Shafaq Yusuf, Maimoona Azhar, Selene Jamall 
World J Gastroenterol 14(43):6627-6631. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6627
Azoxymethane-induced rat aberrant crypt foci: Relevance in studying chemoprevention of colon cancer 
Jayadev Raju 
World J Gastroenterol 14(43):6632-6635. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6632
Genetic determination of irritable bowel syndrome 
Cristina Hotoleanu, Radu Popp, Adrian Pavel Trifa, Laurentiu Nedelcu, Dan L Dumitrascu 
World J Gastroenterol 14(43):6636-6640. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6636
Topic Highlight
How expensive is inflammatory bowel disease? A critical analysis 
Selwyn Odes 
World J Gastroenterol 14(43):6641-6647. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6641
Clinical Research
Distinguishing between parenchymal and anastomotic leakage at duct-to-mucosa pancreatic reconstruction in pancreaticoduodenectomy 
Justin H Nguyen 
World J Gastroenterol 14(43):6648-6654. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6648
Basic Research
Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet 
Hideto Kawaratani, Tatsuhiro Tsujimoto, Toshiyuki Kitazawa, Mitsuteru Kitade, Hitoshi Yoshiji, Masahito Uemura, Hiroshi Fukui 
World J Gastroenterol 14(43):6655-6661. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6655
Gene expression profiling: Canonical molecular changes and clinicopathological features in sporadic colorectal cancers 
Jin Cheon Kim, Seon Young Kim, Seon Ae Roh, Dong-Hyung Cho, Dae Dong Kim, Jeong Hyun Kim, Yong Sung Kim 
World J Gastroenterol 14(43):6662-6672. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6662
Activation of canonical Wnt signaling pathway promotes proliferation and self-renewal of rat hepatic oval cell line WB-F344 in vitro 
Ying Zhang, Xin-Min Li, Fu-Kui Zhang, Bao-En Wang 
World J Gastroenterol 14(43):6673-6680. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6673
Portal venous arterialization resulting in increased portal inflow and portal vein wall thickness in rats 
Wen-Gang Li, Yong-Liang Chen, Jing-Xi Chen, Lei Qu, Bin-Dang Xue, Zhi-Hai Peng, Zhi-Qiang Huang 
World J Gastroenterol 14(43):6681-6688. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6681
Rapid Communication
Co-infection of hepatitis B and hepatitis C virus in human immunodeficiency virus-infected patients in New York City, United States 
Jong Hun Kim, George Psevdos Jr, Jin Suh, Victoria Lee Sharp 
World J Gastroenterol 14(43):6689-6693. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6689
Barium meal follow through with pneumocolon: Screening test for chronic bowel pain 
Sandeep Nijhawan, Saket Kumpawat, P Mallikarjun, RP Bansal, Dinesh Singla, Prachis Ashdhir, Amit Mathur, Ramesh Roop Rai 
World J Gastroenterol 14(43):6694-6698. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6694
Peripheral and mesenteric serum levels of CEA and cytokeratins, staging and histopathological variables in colorectal adenocarcinoma 
Ivan Gregório Ivankovics, Luis César Fernandes, Sarhan Sydeney Saad, Delcio Matos 
World J Gastroenterol 14(43):6699-6703. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6699
Endoscopic and histopathological evaluation of acute gastric injury in high-dose acetaminophen and nonsteroidal anti-inflammatory drug ingestion with suicidal intent 
Aliye Soylu, Can Dolapcioglu, Kemal Dolay, Aydin Ciltas, Nurgul Yasar, Mustafa Kalayci, Halil Alis, Nurten Sever 
World J Gastroenterol 14(43):6704-6710. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6704
Non-traumatic splenic rupture: Report of seven cases and review of the literature 
Ercan Gedik, Sadullah Girgin, Mustafa Aldemir, Celalettin Keles, Mehmet Cudi Tuncer, Ayfer Aktas 
World J Gastroenterol 14(43):6711-6716. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6711
Helicobacter pylori infection and expression of DNA mismatch repair proteins 
Vahid Mirzaee, Mahsa Molaei, Hamid Mohaghegh Shalmani, Mohammad Reza Zali 
World J Gastroenterol 14(43):6717-6721. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6717
Colonoscopic perforation: A report from World Gastroenterology Organization endoscopy training center in Thailand 
Varut Lohsiriwat, Sasithorn Sujarittanakarn, Thawatchai Akaraviputh, Narong Lertakyamanee, Darin Lohsiriwat, Udom Kachinthorn 
World J Gastroenterol 14(43):6722-6725. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6722
A novel device for endoscopic submucosal dissection, the Fork knife 
Hyun Gun Kim, Joo Young Cho, Gene Hyun Bok, Won Young Cho, Wan Jung Kim, Su Jin Hong, Bong Min Ko, Jin Oh Kim, Joon Seong Lee, Moon Sung Lee, Chan Sup Shim 
World J Gastroenterol 14(43):6726-6732. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6726
XRCC1 genetic polymorphism Arg399Gln and gastric cancer risk: A meta-analysis 
Jian Geng, You-Wei Zhang, Gui-Chun Huang, Long-Bang Chen 
World J Gastroenterol 14(43):6733-6737. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6733
Value of ultrasound examination in differential diagnosis of pancreatic lymphoma and pancreatic cancer 
Li Qiu, Yan Luo, Yu-Lan Peng 
World J Gastroenterol 14(43):6738-6742. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6738
Non-thermal ablation of rabbit liver VX2 tumor by pulsed high intensity focused ultrasound with ultrasound contrast agent: Pathological characteristics 
Cheng-Wen Zhou, Fa-Qi Li, Yan Qin, Chun-Mei Liu, Xiao-Lin Zheng, Zhi-Biao Wang 
World J Gastroenterol 14(43):6743-6747. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6743
Case Report
An unusual presentation of primary sclerosing cholangitis 
Franklin Whitney Goldwire, William E Norris, Jonathan M Koff, Zachary D Goodman, Milton T Smith 
World J Gastroenterol 14(43):6748-6749. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6748
Concomitant gastric adenocarcinoma and stromal tumor in a woman with polymyalgia rheumatica 
Panteleimon Kountourakis, Niki Arnogiannaki, Ilias Stavrinides, Nikiforos Apostolikas, Gerasimos Rigatos 
World J Gastroenterol 14(43):6750-6752. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6750
Pneumatosis cystoides intestinalis associated with massive free air mimicking perforated diffuse peritonitis 
Yoichi Sakurai, Masahiro Hikichi, Jun Isogaki, Shinpei Furuta, Risaburo Sunagawa, Kazuki Inaba, Yoshiyuki Komori, Ichiro Uyama 
World J Gastroenterol 14(43):6753-6756. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6753
Gastric outlet obstruction caused by heterotopic pancreas: A case report and a quick review 
Li-Xin Jiang, Jie Xu, Xue-Wen Wang, Fu-Run Zhou, Wei Gao, Guo-Hua Yu, Zhong-Chuan Lv, Hai-Tao Zheng 
World J Gastroenterol 14(43):6757-6759. Published online Nov 21, 2008. doi: 10.3748/wjg.14.6757