Peripheral and mesenteric serum levels of CEA and cytokeratins, staging and histopathological variables in colorectal adenocarcinoma

Table 1 Descriptive measurements of the tumor markers and the histopathological variables and staging of the colorectal adenocarcinoma (mean ± SD)

Variables	CEA (M) ug/L	CEA (P) ug/L	TPA-M (M) U/L	TPA-M (P) U/L
TNM
I	14.96 ± 43.02	15.82 ± 52.37	178.91 ± 116.08	168.44 ± 137.84
II	3.71 ± 3.23	3.10 ± 2.63	148.56 ± 79.25	126.13 ± 82.13
III	11.33 ± 21.21	8.00 ± 16.71	214.94 ± 164.20	151.55 ± 131.75
IV	90.28 ± 190.14	90.69 ± 190.88	578.52 ± 812.53	511.02 ± 692.70
P	0.001	0.001	0.001	0.001
Cell differentiation
PD	22.06 ± 72.07	22.40 ± 72.24	227.35 ± 214.74	197.28 ± 234.32
MD	40.95 ± 116.87	40.52 ± 127.30	392.67 ± 695.62	338.50 ± 589.94
BD	11.40 ± 17.84	9.97 ± 14.84	111.67 ± 46.50	72.53 ± 43.22
P	0.816	0.632	0.212	0.164
Diameter (cm)
Up to 3.9	44.80 ± 155.57	53.88 ± 190.73	194.84 ± 139.81	193.03 ± 230.85
4.0 to 7.9	27.96 ± 86.94	27.18 ± 85.14	331.94 ± 645.83	294.35 ± 561.49
≥ 8.0	34.63 ± 89.26	31.51 ± 89.48	325.34 ± 314.19	248.44 ± 234.79
P	0.106	0.186	0.104	0.197
Macroscopic ulcerated
No	38.21 ± 103.39	36.82 ± 108.08	530.45 ± 997.46	457.95 ± 811.36
Yes	30.01 ± 96.84	30.26 ± 104.16	248.99 ± 257.75	214.44 ± 276.23
P	0.433	0.736	0.014	0.009
Vegetating
No	29.19 ± 103.53	30.94 ± 114.16	233.59 ± 229.94	217.40 ± 284.20
Yes	34.44 ± 93.07	32.51 ± 95.45	388.99 ± 706.77	319.81 ± 583.88
P	0.035	0.197	0.057	0.18
Infiltrative
No	15.71 ± 41.64	15.22 ± 45.76	281.19 ± 394.86	244.83 ± 376.19
Yes	47.00 ± 129.00	47.23 ± 137.53	341.94 ± 637.18	292.49 ± 532.86
P	0.132	0.07	0.415	0.321
Venous invasion
Present	48.41 ± 129.86	53.23 ± 158.57	347.10 ± 282.17	255.56 ± 477.84
Absent	28.09 ± 89.57	26.85 ± 88.36	304.68 ± 575.348	330.35 ± 391.40
P	0.034	0.029	0.163	0.094
Lymp. invasion
Present	49.76 ± 129.89	46.75 ± 125.35	447.89 ± 845.14	227.83 ± 286.49
Absent	23.02 ± 77.03	24.33 ± 92.70	245.69 ± 251.79	353.65 ± 691.80
P	0.095	0.15	0.137	0.527