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Welcome to the World Journal of Clinical Cases

World Journal of Clinical Cases (WJCC, World J Clin Cases) is a high-quality, online, open-access, single-blind peer-reviewed journal published by the Baishideng Publishing Group. WJCC accepts both solicited and unsolicited manuscripts. Articles published in WJCC are high-quality, clinical, influential research articles by established academic authors as well as new researchers. The paramount objective of WJCC is to showcase and promote distinguished research in the field of clinical medicine, to help advance development of this field. The types of articles published in WJCC include Editorial, Opinion Review, Frontier, Review, Minireview, Clinical Research, Systematic Review, Meta-analysis, Evidence-based Medicine, Field of Vision, Clinical Guidelines, Letter to the Editor, and Case Report. Submit here >>

2019 Published Issues
19 18 17 16 15 14 13 12 11 10 9 8 7 6 5 4 3 2 1
  • Dennis A Bloomfield, FACC, FACP, FRACP, FRCP (Hon), MD, MRCP, Professor, (E-mail: dbloomfield@rumcsi.org) Clinical Research, Richmond University Medical Center, New York, NY 10310, United States
  • Bao-Gan Peng, MD, PhD, Chief Doctor, Professor, (E-mail:pengbaogan@163.com) Department of Spinal Surgery, General Hospital of Armed Police Force, Beijing 100039, China
  • Sandro Vento, MD, Dean, Full Professor, (E-mail: svento@puthisastra.edu.kh) Faculty of Medicine, University of Puthisastra, Phnom Penh , Cambodia
The WJCC is now abstracted and indexed in PubMed, PubMed Central, Science Citation Index Expanded (SCIE, also known as SciSearch®), Journal Citation Reports/Science Edition, Current Contents®/Clinical Medicine, China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (CSTJ), and Superstar Journals Database.
Journal Metrics
The 2019 Edition of Journal Citation Reports cites the 2018 impact factor for WJCC as 1.153 (5-year impact factor: N/A), ranking WJCC as 99 among 160 journals in Medicine, General and Internal (quartile in category Q3).
2307-8960 (online)
DNA methylation detection methods used in colorectal cancer 
Yu-Xia Zhan, Guang-Hua Luo 
World J Clin Cases 7(19):2916-2929. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2916
Case Control Study
Expression and predictive value of miR-489 and miR-21 in melanoma metastasis 
Hao Mo, Jian Guan, Zhen-Chao Yuan, Xiang Lin, Zhen-Jie Wu, Bin Liu, Ju-Liang He 
World J Clin Cases 7(19):2930-2941. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2930
Observational Study
Association of stiff-person syndrome with autoimmune endocrine diseases 
Yi-Yin Lee, I-Wen Chen, Szu-Tah Chen, Chih-Ching Wang 
World J Clin Cases 7(19):2942-2952. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2942
Hyperthyroid heart disease in pregnancy: Retrospective analysis of a case series and review of the literature 
Dan Shan, Yi Bai, Qiu-He Chen, Yu-Xia Wu, Qian Chen, Ya-Yi Hu 
World J Clin Cases 7(19):2953-2962. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2953
Changes of serum inflammatory factors and miR-145 expression in patients with osteoarthritis before and after treatment and their clinical value 
Xiao-Zhen Wang, Wen-Xue Li 
World J Clin Cases 7(19):2963-2975. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2963
Prospective Study
Immediate muscle strengthening by an end-effector type gait robot with reduced real-time use of leg muscles: A case series and review of literature 
Chang Ho Hwang 
World J Clin Cases 7(19):2976-2985. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2976
Randomized Clinical Trial
Comparison of perceived pain and patients’ satisfaction with traditional local anesthesia and single tooth anesthesia: A randomized clinical trial 
Mohammad I Al-Obaida, Mehdiya Haider, Rawan Hashim, Wafa AlGheriri, Sree Lalita Celur, Samar A Al-Saleh, Ebtissam M Al-Madi 
World J Clin Cases 7(19):2986-2994. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2986
Systematic Review
Treatment of laryngopharyngeal reflux disease: A systematic review 
Jerome R Lechien, Francois Mouawad, Maria R Barillari, Andrea Nacci, Seyyedeh Maryam Khoddami, Necati Enver, Sampath Kumar Raghunandhan, Christian Calvo-Henriquez, Young-Gyu Eun, Sven Saussez 
World J Clin Cases 7(19):2995-3011. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2995
Case Report
Keratoconus in a patient with Alport syndrome: A case report 
Majid Moshirfar, David F Skanchy, Aaron T Gomez, Yasmyne C Ronquillo, Benjamin Buckner, Phillip C Hoopes 
World J Clin Cases 7(19):3012-3017. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3012
Successful multidisciplinary clinical approach and molecular characterization by whole transcriptome sequencing of a cardiac myxofibrosarcoma: A case report 
Maristella Saponara, Valentina Indio, Carmine Pizzi, Elena-Daniela Serban, Milena Urbini, Annalisa Astolfi, Pasquale Paolisso, Sofia Martin Suarez, Margherita Nannini, Davide Pacini, Valentina Agostini, Ornella Leone, Valentina Ambrosini, Giuseppe Tarantino, Stefano Fanti, Fabio Niro, Francesco Buia, Domenico Attinà, Maria Abbondanza Pantaleo 
World J Clin Cases 7(19):3018-3026. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3018
Laparoscopic hysterectomy as optimal approach for 5400 grams uterus with associated polycythemia: A case report 
Antonio Macciò, Giacomo Chiappe, Fabrizio Lavra, Elisabetta Sanna, Romualdo Nieddu, Clelia Madeddu 
World J Clin Cases 7(19):3027-3032. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3027
Malignant sweat gland tumor of breast arising in pre-existing benign tumor: A case report 
Jin Kyung An, Jeong Joo Woo, Young Ok Hong 
World J Clin Cases 7(19):3033-3038. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3033
Bronchobiliary fistula after ramucirumab treatment for advanced gastric cancer: A case report 
Hong-Beum Kim, Yong Sub Na, Hee-Jeong Lee, Sang-Gon Park 
World J Clin Cases 7(19):3039-3046. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3039
Severe heterotopic ossification in a seronegative spondyloarthritis patient after cervical Bryan disc arthroplasty: A case report 
Chih-Wei Huang, Chien-Lun Tang, Hung-Chuan Pan, Chung-Yuh Tzeng, Hsi-Kai Tsou 
World J Clin Cases 7(19):3047-3054. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3047
Underlying IgM heavy chain amyloidosis in treatment-refractory IgA nephropathy: A case report 
Hai-Ting Wu, Yu-Bing Wen, Wei Ye, Bing-Yan Liu, Kai-Ni Shen, Rui-Tong Gao, Ming-Xi Li 
World J Clin Cases 7(19):3055-3061. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3055
Diagnosis of myocardial infarction with nonobstructive coronary arteries in a young man in the setting of acute myocardial infarction after endoscopic retrograde cholangiopancreatography: A case report 
Dong Li, Yan Li, Xuan Wang, Yang Wu, Xiao-Yun Cui, Ji-Qiang Hu, Bin Li, Qian Lin 
World J Clin Cases 7(19):3062-3068. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3062
Hemophagocytic lymphohistiocytosis complicated by polyserositis: A case report 
Ping Zhu, Qing Ye, Ting-Hong Li, Tao Han, Feng-Mei Wang 
World J Clin Cases 7(19):3069-3073. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3069
Hair regrowth following fecal microbiota transplantation in an elderly patient with alopecia areata: A case report and review of the literature 
Wen-Rui Xie, Xiao-Ya Yang, Harry Hua-Xiang Xia, Li-Hao Wu, Xing-Xiang He 
World J Clin Cases 7(19):3074-3081. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3074
How should congenital absence of cruciate ligaments be treated? A case report and literature review 
Ran Lu, Dong-Ping Zhu, Neng Chen, He Sun, Ze-Hui Li, Xue-Wei Cao 
World J Clin Cases 7(19):3082-3089. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3082
Kaposi’s sarcoma manifested as lower gastrointestinal bleeding in a HIV/HBV-co-infected liver cirrhosis patient: A case report 
Qi-Hui Zhou, Yong-Zheng Guo, Xia-Hong Dai, Biao Zhu 
World J Clin Cases 7(19):3090-3097. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3090
Primary renal synovial sarcoma: A case report 
Huai-Jie Cai, Nan Cao, Wei Wang, Fan-Lei Kong, Xi-Xi Sun, Bin Huang 
World J Clin Cases 7(19):3098-3103. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3098
Type I neurofibromatosis with spindle cell sarcoma: A case report 
Yu Zhang, Jiao-Jiao Chao, Xiu-Feng Liu, Shu-Kui Qin 
World J Clin Cases 7(19):3104-3110. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3104
Primary hypoparathyroidism accompanied by rhabdomyolysis induced by infection: A case report 
Li-Na Ding, Yi Wang, Jun Tian, Li-Fang Ye, Shi Chen, Shi-Min Wu, Wen-Bin Shang 
World J Clin Cases 7(19):3111-3119. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3111
Effects of combined rTMS and visual feedback on the rehabilitation of supernumerary phantom limbs in a patient with spinal cord injury: A case report 
Yin-Shan Lu, Pei Tong, Tie-Cheng Guo, Xin-Hua Ding, Song Zhang, Xiu-Juan Zhang 
World J Clin Cases 7(19):3120-3125. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3120
Clear cell sarcoma of soft tissue in pleural cavity: A case report 
Yang-Tian Chen, Zhi Yang, Huan Li, Chen-Hui Ni 
World J Clin Cases 7(19):3126-3131. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3126
Primary hyperparathyroidism in a woman with multiple tumors: A case report 
Can-Can Hui, Xue Zhang, Jian-Ran Sun, Da-Tong Deng 
World J Clin Cases 7(19):3132-3137. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3132
Gastric adenocarcinoma mimicking a submucosal tumor: A case report 
Xiao-Li Cheng, Hua Liu 
World J Clin Cases 7(19):3138-3144. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3138
Hypereosinophilia, mastectomy, and nephrotic syndrome in a male patient: A case report 
Jian Wu, Peng Li, Yu Chen, Xiang-Hong Yang, Meng-Yun Lei, Li Zhao 
World J Clin Cases 7(19):3145-3152. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3145
Flapless immediate implant placement into fresh molar extraction socket using platelet-rich fibrin: A case report 
Xiao-Lin Sun, Mahmoud Mudalal, Man-Lin Qi, Yue Sun, Liu-Yi Du, Zhan-Qi Wang, Yan-Min Zhou 
World J Clin Cases 7(19):3153-3159. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3153
Advanced primary amelanotic malignant melanoma of the esophagus: A case report 
Ruo-Xi Zhang, Ya-Ying Li, Chang-Jie Liu, Wei-Na Wang, Ying Cao, Yong-Hua Bai, Ti-Jiang Zhang 
World J Clin Cases 7(19):3160-3167. Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3160