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Editorials
Molecular biology of Barrett’s esophagus and esophageal cancer: role of p53 
Alan G. Casson 
World J Gastroenterol 4(4):277-279. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.277
A review of reflux esophagitis around the world 
Edwin J. Zarling 
World J Gastroenterol 4(4):280-284. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.280
Therapy of acute severe pancreatitis awaits further improvement 
Xian-Zhong Wu 
World J Gastroenterol 4(4):285-286. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.285
Original Articles
Apoptosis and its relationship with cell proliferation, p53, Waf1p21, bcl-2 and c-myc in esophageal carcinogenesis studied with a high-risk population in northern China 
Li-Dong Wang, Qi Zhou, Jun-Ping Wei, Wan-Cai Yang, Xin Zhao, Li-Xia Wang, Jian-Xiang Zou, Shan-Shan Gao, Yong-Xin Li, C.S. Yang 
World J Gastroenterol 4(4):287-293. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.287
Expression of alpha fetoprotein messenger RNA in BEL-7404 human hepatoma cells and effect of L-4-oxalysine on the expression 
Xing-Wang Wang, Bin Xu 
World J Gastroenterol 4(4):294-297. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.294
Anal cancer in Chinese: human papillomavirus infection and altered expression of p53 
Mao-De Lai, Min-Jie Luo, Jian-Er Yao, Pei-Hui Chen 
World J Gastroenterol 4(4):298-302. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.298
Radioimmunoimaging of colorectal cancer using 99mTc-labeled monoclonal antibody 
Jin-Yue Hu, Jian-Zhi Su, Zhi-Ming Pi, Jian-Gao Zhu, Guo-Hua Zhou, Qu-Bing Sun 
World J Gastroenterol 4(4):303-306. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.303
Modification of ricin and its hepatotoxicity and activity against hepatocellular cancer in mice 
Wen-Xue Wang, Ju-Ying Dong, Si-Yuan Zhou, Wen-Li Li, Ying Zhao 
World J Gastroenterol 4(4):307-310. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.307
Effect of cytokines on liver necrosis 
Yan-Yan Yu, Chong-Wen Si, Xiu-Lin Tian, Qun He, Hai-Peng Xue 
World J Gastroenterol 4(4):311-313. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.311
Phase tissue intercellular adhesion molecule-1 expression in nude mice human liver cancer metastasis model 
Jing-Jing Sun, Xin-Da Zhou, Yin-Kun Liu, Ge Zhou 
World J Gastroenterol 4(4):314-316. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.314
Reversing effect of Tanshinone on malignant phenotypes of human hepatocarcinoma cell line 
Shu-Lan Yuan, Ren-Min Huang, Xiu-Jie Wang, Yi Song, Guang-Qi Huang 
World J Gastroenterol 4(4):317-319. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.317
HBx-DNA probe preparation and its application in study of hepatocarcinogenesis 
Feng-Guang Gao, Wen-Sheng Sun, Ying-Lin Cao, Li-Ning Zhang, Jing Song, Hua-Fen Li, Shi-Kun Yan 
World J Gastroenterol 4(4):320-322. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.320
Expression and kinetic changes of alkaline phosphatase and its isoenzymes in experimental rat hepatoma 
Ming-Bing Xiao, Deng-Fu Yao, Hong Zhang, Hui Qiang, Jie-Fei Huang, Qun Wei, Feng Jiang 
World J Gastroenterol 4(4):323-325. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.323
Orientated thermotherapy of ferromagnetic thermoseed in hepatic tumors 
Yue-Chun Geng, Xiang-Xiang Wang, Yun Ma, Yan Hu, Ren-Li Zhang 
World J Gastroenterol 4(4):326-328. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.326
Effect of endotoxin on fibronectin synthesis of rat primary cultured hepatocytes 
Jin-Bin Jia, De-Wu Han, Rui-Ling Xu, Fei Gao, Long-Feng Zhao, Yuan-Chang Zhao, Jin-Pin Yan, Xue-Hui Ma 
World J Gastroenterol 4(4):329-331. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.329
Comparative studies on epithelial lesions at gastric cardia and pyloric antrum in subjects from a high incidence area for esophageal cancer in Henan, China 
Shan-Shan Gao, Qi Zhou, Yong-Xin Li, Yong-Min Bai, Zuo-Yu Zheng, Jian-Xiang Zou, Gang Liu, Zong-Min Fan, Yi-Jun Qi, Xin Zhao, Li-Dong Wang 
World J Gastroenterol 4(4):332-333. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.332
Two novel gastric cancer-associated genes identified by differential display 
Han You, Bing Xiao, Da-Xiang Cui, Yong-Quan Shi, Dai-Ming Fan 
World J Gastroenterol 4(4):334-336. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.334
Changes of lipid metabolism in plasma, liver and bile during cholesterol gallstone formation in rabbit model 
Ji-Chun Zhao, Lu-Jia Xiao, Hong Zhu, Ye Shu, Nan-Sheng Cheng 
World J Gastroenterol 4(4):337-339. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.337
Copper-chelating therapeutic effect in Wilson disease with different clinical phenotypes and polymorphisms of ATP7B gene 
Ming-Shan Ren, Wen-Bin Hu, Zhi Zhang, Shuang-Wu Ju, Yu-Xin Fan, Gong-Qiang Wang, Ren-Min Yang 
World J Gastroenterol 4(4):340-342. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.340
Role and pitfalls of hepatic helical multi-phase CT scanning in differential diagnosis of small hemangioma and small hepatocellular carcinoma 
Fu-Hua Yan, Meng-Su Zeng, Kang-Rong Zhou 
World J Gastroenterol 4(4):343-347. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.343
Combined Traditional and Modera Medicine
Effects of Fuzheng Huayu 319 recipe on liver fibrosis in chronic hepatitis B 
Ping Liu, Cheng Liu, Lie-Ming Xu, Yi-Yang Hu, Hui-Ming Xue, Cheng-Hai Liu, Zhi-Qing Zhang 
World J Gastroenterol 4(4):348-353. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.348
Effects of Dangshen on isolated gastric muscle strips in rats 
Tian-Zhen Zheng, Wei Li, Song-Yi Qu, Yong-Ming Ma, Yong-Hui Ding, Yu-Ling Wei 
World J Gastroenterol 4(4):354-356. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.354
Traditional Chinese medicine "Qing Yi Tang" alleviates oxygen free radical injury in acute necrotizing pancreatits 
Zhan-Liang Li, Cheng-Tang Wu, Lian-Rong Lu, Xiao-Feng Zhu, De-Xin Xiong 
World J Gastroenterol 4(4):357-359. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.357
Review
Traditional Chinese medicine for primary liver cancer 
Zuo-Qing Li 
World J Gastroenterol 4(4):360-364. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.360
Brief Reports
Changes of p53 protein blood level in esophageal cancer patients and normal subjects from a high incidence area in Henan, China 
Guo-Qiang Yu, Qi Zhou, Ivan Ding, Shan-Shan Gao, Zuo-Yu Zheng, Jian-Xiang Zou, Yong-Xin Li, Li-Dong Wang 
World J Gastroenterol 4(4):365-366. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.365
Functional dyspepsia of ulcer-dysmotility type: clinical incidence and therapeutic strategy 
Xiao-Zhong Wang, Gu-Zhen Lin 
World J Gastroenterol 4(4):367-368. Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.367