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Open-Access Journal
Editorial
Management of acute pancreatitis in Japan: Analysis of nationwide epidemiological survey 
Shin Hamada, Atsushi Masamune, Tooru Shimosegawa 
World J Gastroenterol 22(28):6335-6344. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6335
Topic Highlight
Mechanisms of resistance to anti-epidermal growth factor receptor inhibitors in metastatic colorectal cancer 
Vincenzo Sforza, Erika Martinelli, Fortunato Ciardiello, Valentina Gambardella, Stefania Napolitano, Giulia Martini, Carminia della Corte, Claudia Cardone, Marianna L Ferrara, Alfonso Reginelli, Giuseppina Liguori, Giulio Belli, Teresa Troiani 
World J Gastroenterol 22(28):6345-6361. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6345
Immunotherapy in human colorectal cancer: Challenges and prospective 
Xuan Sun, Jian Suo, Jun Yan 
World J Gastroenterol 22(28):6362-6372. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6362
Immunological battlefield in gastric cancer and role of immunotherapies 
Minyu Wang, Rita A Busuttil, Sharon Pattison, Paul J Neeson, Alex Boussioutas 
World J Gastroenterol 22(28):6373-6384. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6373
Hepatitis C virus: Promising discoveries and new treatments 
Juliana Cristina Santiago Bastos, Marina Aiello Padilla, Leonardo Cardia Caserta, Noelle Miotto, Aline Gonzalez Vigani, Clarice Weis Arns 
World J Gastroenterol 22(28):6393-6401. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6393
Personality traits and emotional patterns in irritable bowel syndrome 
Maria Rosaria A Muscatello, Antonio Bruno, Carmela Mento, Gianluca Pandolfo, Rocco A Zoccali 
World J Gastroenterol 22(28):6402-6415. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6402
Metabolic complications in liver transplant recipients 
Miguel Jiménez-Pérez, Rocío González-Grande, Edith Omonte Guzmán, Víctor Amo Trillo, Juan Miguel Rodrigo López 
World J Gastroenterol 22(28):6416-6423. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6416
Re-evaluation of classical prognostic factors in resectable ductal adenocarcinoma of the pancreas 
Daniel Åkerberg, Daniel Ansari, Roland Andersson 
World J Gastroenterol 22(28):6424-6433. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6424
Review
Pathophysiological role of guanylate-binding proteins in gastrointestinal diseases 
Nathalie Britzen-Laurent, Christian Herrmann, Elisabeth Naschberger, Roland S Croner, Michael Stürzl 
World J Gastroenterol 22(28):6434-6443. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6434
Management of psoriasis patients with hepatitis B or hepatitis C virus infection 
Claudio Bonifati, Viviana Lora, Dario Graceffa, Lorenzo Nosotti 
World J Gastroenterol 22(28):6444-6455. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6444
Enhanced recovery pathways in pancreatic surgery: State of the art 
Nicolò Pecorelli, Sara Nobile, Stefano Partelli, Luca Cardinali, Stefano Crippa, Gianpaolo Balzano, Luigi Beretta, Massimo Falconi 
World J Gastroenterol 22(28):6456-6468. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6456
Specific CD8+ T cell response immunotherapy for hepatocellular carcinoma and viral hepatitis 
Elia Moreno-Cubero, Juan-Ramón Larrubia 
World J Gastroenterol 22(28):6469-6483. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6469
Prevention and management of hepatitis B virus reactivation in patients with hematological malignancies treated with anticancer therapy 
Man Fai Law, Rita Ho, Carmen KM Cheung, Lydia HP Tam, Karen Ma, Kent CY So, Bonaventure Ip, Jacqueline So, Jennifer Lai, Joyce Ng, Tommy HC Tam 
World J Gastroenterol 22(28):6484-6500. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6484
Minireviews
Polyethylene glycols: An effective strategy for limiting liver ischemia reperfusion injury 
Gianfranco Pasut, Arnau Panisello, Emma Folch-Puy, Alexandre Lopez, Carlos Castro-Benítez, Maria Calvo, Teresa Carbonell, Agustín García-Gil, René Adam, Joan Roselló-Catafau 
World J Gastroenterol 22(28):6501-6508. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6501
Basic Study
c-Jun N-terminal kinase-mediated Rubicon expression enhances hepatocyte lipoapoptosis and promotes hepatocyte ballooning 
Akiko Suzuki, Keisuke Kakisaka, Yuji Suzuki, Ting Wang, Yasuhiro Takikawa 
World J Gastroenterol 22(28):6509-6519. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6509
Case Control Study
TCF7L2 rs7903146 polymorphism is associated with gastric cancer: A case-control study in the Venezuelan population 
Keila Torres, Luis Labrador, Elvis Valderrama, Miguel Angel Chiurillo 
World J Gastroenterol 22(28):6520-6526. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6520
Observational Study
Trends and predictions for gastric cancer mortality in Brazil 
Angela Carolina Brandão de Souza Giusti, Pétala Tuani Candido de Oliveira Salvador, Juliano dos Santos, Karina Cardoso Meira, Amanda Rodrigues Camacho, Raphael Mendonça Guimarães, Dyego LB Souza 
World J Gastroenterol 22(28):6527-6538. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6527
Prospective Study
Can optical diagnosis of small colon polyps be accurate? Comparing standard scope without narrow banding to high definition scope with narrow banding 
Hassan Ashktorab, Firoozeh Etaati, Farahnaz Rezaeean, Mehdi Nouraie, Mansour Paydar, Hassan Hassanzadeh Namin, Andrew Sanderson, Rehana Begum, Kawtar Alkhalloufi, Hassan Brim, Adeyinka O Laiyemo 
World J Gastroenterol 22(28):6539-6546. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6539
Systematic Reviews
Epidemiology of functional gastrointestinal disorders in infants and toddlers: A systematic review 
Ana Paula Ferreira-Maia, Alicia Matijasevich, Yuan-Pang Wang 
World J Gastroenterol 22(28):6547-6558. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6547
Case Report
Systemic mastocytosis: A rare cause of non-cirrhotic portal hypertension 
Cláudio Martins, Cristina Teixeira, Suzane Ribeiro, Daniel Trabulo, Cláudia Cardoso, João Mangualde, Ricardo Freire, Élia Gamito, Ana Luísa Alves, Isabelle Cremers, Cecília Alves, Anabela Neves, Ana Paula Oliveira 
World J Gastroenterol 22(28):6559-6564. Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6559