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Topic Highlight
Molecular mechanisms of triggering, amplifying and targeting RANK signaling in osteoclasts 
Yukiko Kuroda, Koichi Matsuo 
World J Orthop 3(11):167-174. Published online Nov 18, 2012. doi: 10.5312/wjo.v3.i11.167
New roles of osteoblasts involved in osteoclast differentiation 
Teruhito Yamashita, Naoyuki Takahashi, Nobuyuki Udagawa 
World J Orthop 3(11):175-181. Published online Nov 18, 2012. doi: 10.5312/wjo.v3.i11.175
Review
Management of postoperative spinal infections 
Vishal Hegde, Dennis S Meredith, Christopher K Kepler, Russel C Huang 
World J Orthop 3(11):182-189. Published online Nov 18, 2012. doi: 10.5312/wjo.v3.i11.182
Energy metabolism and the skeleton: Reciprocal interplay 
Patrizia D Amelio, Anna Panico, Elena Spertino, Giovanni Carlo Isaia 
World J Orthop 3(11):190-198. Published online Nov 18, 2012. doi: 10.5312/wjo.v3.i11.190