Energy metabolism and the skeleton: Reciprocal interplay

Figure 1 Schematic representation of the relationship between fat tissue, brain, gut, and bone mediated by leptin and serotonin.

Figure 2 Schematic representation of the interaction between bone and glucose tolerance mediated by insulin and undercarboxylated osteocalcin.

Figure 3 Schematic representation of the multiple interactions between pancreatic β-cells, adipocytes, muscle cells, and bone mediated by undercarboxylated osteocalcin.