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Frontier
Discovery and characterization of the first non-coding RNA that regulates gene expression, micF RNA: A historical perspective 
Nicholas Delihas 
World J Biol Chem 6(4):272-280. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.272
Review
Targeting amino acid metabolism in cancer growth and anti-tumor immune response 
Elitsa Ananieva 
World J Biol Chem 6(4):281-289. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.281
Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer 
Sherri Rennoll, Gregory Yochum 
World J Biol Chem 6(4):290-300. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.290
Crosstalk between mitochondria and peroxisomes 
Jean Demarquoy, Françoise Le Borgne 
World J Biol Chem 6(4):301-309. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.301
Modulation of the matrix redox signaling by mitochondrial Ca2+ 
Jaime Santo-Domingo, Andreas Wiederkehr, Umberto De Marchi 
World J Biol Chem 6(4):310-323. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.310
Signal transducer and activator of transcription 3 regulation by novel binding partners 
Tadashi Matsuda, Ryuta Muromoto, Yuichi Sekine, Sumihito Togi, Yuichi Kitai, Shigeyuki Kon, Kenji Oritani 
World J Biol Chem 6(4):324-332. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.324
Global histone post-translational modifications and cancer: Biomarkers for diagnosis, prognosis and treatment? 
Shafqat Ali Khan, Divya Reddy, Sanjay Gupta 
World J Biol Chem 6(4):333-345. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.333
Minireviews
Cyclin A2: At the crossroads of cell cycle and cell invasion 
Abdelhalim Loukil, Caroline T Cheung, Nawal Bendris, Bénédicte Lemmers, Marion Peter, Jean Marie Blanchard 
World J Biol Chem 6(4):346-350. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.346
Klotho in cardiovascular disease: Current and future perspectives 
Javier Donate-Correa, Ernesto Martín-Núñez, Carmen Mora-Fernández, Mercedes Muros-de-Fuentes, Nayra Pérez-Delgado, Juan F Navarro-González 
World J Biol Chem 6(4):351-357. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.351
Caldecrin: A pancreas-derived hypocalcemic factor, regulates osteoclast formation and function 
Mineko Tomomura, Akito Tomomura 
World J Biol Chem 6(4):358-365. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.358
Basic Study
Disruption of NAD+ binding site in glyceraldehyde 3-phosphate dehydrogenase affects its intranuclear interactions 
Manali Phadke, Natalia Krynetskaia, Anurag Mishra, Carlos Barrero, Salim Merali, Scott A Gothe, Evgeny Krynetskiy 
World J Biol Chem 6(4):366-378. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.366
Connective tissue growth factor differentially binds to members of the cystine knot superfamily and potentiates platelet-derived growth factor-B signaling in rabbit corneal fibroblast cells 
Liya Pi, Pei-Yu Chung, Sriniwas Sriram, Masmudur M Rahman, Wen-Yuan Song, Edward W Scott, Bryon E Petersen, Gregory S Schultz 
World J Biol Chem 6(4):379-388. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.379
DNA microarray unravels rapid changes in transcriptome of MK-801 treated rat brain 
Yuka Kobayashi, Sofya P Kulikova, Junko Shibato, Randeep Rakwal, Hiroyuki Satoh, Didier Pinault, Yoshinori Masuo 
World J Biol Chem 6(4):389-408. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.389
JAK3 inhibitor VI is a mutant specific inhibitor for epidermal growth factor receptor with the gatekeeper mutation T790M 
Naoyuki Nishiya, Yasumitsu Sakamoto, Yusuke Oku, Takamasa Nonaka, Yoshimasa Uehara 
World J Biol Chem 6(4):409-418. Published online Nov 26, 2015. doi: 10.4331/wjbc.v6.i4.409