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Contents Volume 17 Issue 9 September 26, 2025

Review

Neural crest-derived mesenchymal stem cells: Fates and perspectives

Wen-Peng Song, Deng-Sheng Xia, Si-Jia Chen, Yi-Lin He

World J Stem Cells 17(9):107689. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.107689

Abstract (145) | Core Tip (154) | Full Article (HTML) (716) | Figures (1-1) (88) | Tables (1-4) (209) | Full Article (PDF)-1659K (169) | Full Article with Cover (PDF)-2004K (92) | Full Article (XML)-359K (45) | Audio-1644K (47) | Received: 03/27/2025 | Revised: 04/25/2025 | Accepted: 08/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (18) | Timeline of Article Publication (0) | Cite | (53) | (54) | (0) | (0) | (0) | (10) | (1319) | (5) | Open

Stem cell-based cartilage regeneration: Biological strategies, engineering innovations, and clinical translation

Bo Cong, Feng-Hua Zhang, Hai-Guang Zhang

World J Stem Cells 17(9):108523. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108523

Abstract (170) | Core Tip (126) | Full Article (HTML) (1130) | Figures (1-2) (92) | Tables (1-2) (121) | Full Article (PDF)-1838K (147) | Full Article with Cover (PDF)-2183K (103) | Full Article (XML)-213K (56) | Audio-882K (84) | Received: 04/16/2025 | Revised: 05/27/2025 | Accepted: 07/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (3) | Timeline of Article Publication (0) | Cite | (49) | (59) | (0) | (0) | (0) | (1) | (1) | (1649) | (9) | Open

HOX and MEINOX in cellular plasticity, fibrosis, and cancer

Mustafa Keleş, Aysen Gunel-Ozcan

World J Stem Cells 17(9):109102. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109102

Abstract (114) | Core Tip (128) | Full Article (HTML) (578) | Figures (1-4) (117) | Tables (1-8) (130) | Full Article (PDF)-3940K (137) | Full Article with Cover (PDF)-4285K (76) | Full Article (XML)-505K (67) | Audio-281K (40) | Received: 04/29/2025 | Revised: 06/16/2025 | Accepted: 08/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (305) | Timeline of Article Publication (0) | Cite | (47) | (48) | (0) | (0) | (0) | (1105) | Open

Minireviews

Dual role and clinical application of extracellular vesicles in acute respiratory distress syndrome: Mechanism analysis and translational challenges

Yi-Fu Tie, Han Liu, Tong Zhang, Tian-Wei Meng, Qun Liang

World J Stem Cells 17(9):108657. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108657

Abstract (127) | Core Tip (110) | Full Article (HTML) (396) | Figures (1-2) (107) | Tables (1-1) (106) | Full Article (PDF)-3728K (87) | Full Article with Cover (PDF)-4070K (53) | Full Article (XML)-167K (43) | Audio-534K (40) | Received: 04/19/2025 | Revised: 05/14/2025 | Accepted: 08/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (86) | Timeline of Article Publication (0) | Cite | (43) | (46) | (0) | (0) | (0) | (792) | (2) | Open

Post-translational modifications in osteogenic differentiation of oral-derived stem cells: Mechanisms and clinical implications

Zhuo-Jin Shi, Wei Liu

World J Stem Cells 17(9):109662. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109662

Abstract (133) | Core Tip (115) | Full Article (HTML) (441) | Figures (1-1) (121) | Tables (1-3) (125) | Full Article (PDF)-742K (114) | Full Article with Cover (PDF)-1086K (80) | Full Article (XML)-226K (50) | Audio-1379K (47) | Received: 05/17/2025 | Revised: 06/22/2025 | Accepted: 08/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (4) | Timeline of Article Publication (11) | Cite | (46) | (46) | (0) | (0) | (0) | (931) | (2) | Open

Retrospective Study

Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer

Tao Lin, Si-Cong Jiang, Xian-Ming He, Wen-Zhen Xu, Cai-Jin Jin, You-Dan Guo

World J Stem Cells 17(9):106381. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.106381

Abstract (137) | Core Tip (132) | Full Article (HTML) (428) | Figures (1-2) (86) | Tables (1-2) (99) | Full Article (PDF)-815K (84) | Full Article with Cover (PDF)-1161K (56) | Full Article (XML)-114K (57) | Audio-84K (47) | Received: 03/20/2025 | Revised: 05/16/2025 | Accepted: 08/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (0) | Timeline of Article Publication (1) | Cite | (46) | (44) | (0) | (0) | (0) | (810) | (1) | Open

Randomized Controlled Trial

Combined mesenchymal and neural stem cell therapy enhances neurological recovery in cerebral infarction

Ting Yang, Hui Yu, Dong Han, Zheng Xie

World J Stem Cells 17(9):110663. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.110663

Abstract (134) | Core Tip (161) | Full Article (HTML) (643) | Figures (1-1) (83) | Tables (1-4) (85) | Full Article (PDF)-920K (103) | Full Article with Cover (PDF)-1266K (69) | Full Article (XML)-90K (44) | Audio-593K (38) | Received: 06/13/2025 | Revised: 07/22/2025 | Accepted: 09/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (226) | Timeline of Article Publication (1) | Cite | (47) | (41) | (0) | (0) | (0) | (1027) | (3) | Open

Basic Study

Quercetin pretreated umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease via IL-10 /Janus kinase 2/STAT3 signaling

Meng-Yue Shi, Lian Liu, Fu-Yuan Yang

World J Stem Cells 17(9):105896. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.105896

Abstract (122) | Core Tip (114) | Full Article (HTML) (502) | Figures (1-7) (100) | Tables (1-4) (103) | Full Article (PDF)-16218K (83) | Full Article with Cover (PDF)-16564K (65) | Full Article (XML)-136K (55) | Audio-233K (59) | Received: 02/09/2025 | Revised: 04/07/2025 | Accepted: 08/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (7) | Timeline of Article Publication (2) | Cite | (52) | (59) | (0) | (0) | (0) | (15) | (908) | Open

Bone marrow mesenchymal stem cell-derived exosomal lactate dehydrogenase A promotes tendon-bone healing via histone lactylation-mediated cartilage regeneration

Ting Zhang, Qing Huang, Kai-Feng Gan

World J Stem Cells 17(9):106282. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.106282

Abstract (132) | Core Tip (136) | Full Article (HTML) (417) | Figures (1-5) (98) | Tables (1-2) (97) | Full Article (PDF)-6246K (100) | Full Article with Cover (PDF)-6589K (86) | Full Article (XML)-107K (44) | Audio-68K (81) | Supplementary Material-303K (47) | Received: 02/26/2025 | Revised: 03/27/2025 | Accepted: 09/05/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (2) | Timeline of Article Publication (2) | Cite | (51) | (44) | (0) | (0) | (0) | (1) | (842) | (4) | Open

Wumei Pills enhance intestinal stem cell - mediated repair in chemotherapy-induced mucositis via Lactobacillus reuteri - dependent modulation of the gut microbiota

Dong-Xue Lu, Zi-Xuan Wang, Xi-Min Liu, Hua Wu, Li-Jiang Ji, Jing Yan

World J Stem Cells 17(9):107025. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.107025

Abstract (133) | Core Tip (132) | Full Article (HTML) (474) | Figures (1-7) (103) | Tables (1-1) (92) | Full Article (PDF)-8376K (100) | Full Article with Cover (PDF)-8721K (65) | Full Article (XML)-113K (46) | Audio-528K (44) | Received: 03/15/2025 | Revised: 05/10/2025 | Accepted: 08/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (2) | Timeline of Article Publication (0) | Cite | (45) | (63) | (0) | (0) | (0) | (23) | (880) | (2) | Open

Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging

Hyunjun Ahn, Ho-Seong Han, Kye-Ho Lee

World J Stem Cells 17(9):108049. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108049

Abstract (155) | Core Tip (146) | Full Article (HTML) (1017) | Figures (1-4) (104) | Tables (1-1) (128) | Full Article (PDF)-12509K (137) | Full Article with Cover (PDF)-12853K (79) | Full Article (XML)-114K (47) | Audio-822K (65) | Supplementary Material-463K (43) | Received: 04/09/2025 | Revised: 06/12/2025 | Accepted: 08/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (17) | Timeline of Article Publication (4) | Cite | (42) | (45) | (0) | (0) | (0) | (1512) | Open

Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms

Xing Jiang, Zhi-Min Lu, Qing-Lu Wang, Ying Luo, Jie Zhang

World J Stem Cells 17(9):109330. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109330

Abstract (122) | Core Tip (114) | Full Article (HTML) (432) | Figures (1-5) (88) | Tables (1-1) (87) | Full Article (PDF)-5590K (96) | Full Article with Cover (PDF)-5933K (59) | Full Article (XML)-169K (55) | Audio-1583K (43) | Received: 05/08/2025 | Revised: 06/18/2025 | Accepted: 08/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (86) | Timeline of Article Publication (0) | Cite | (47) | (57) | (0) | (0) | (0) | (9) | (1) | (817) | (3) | Open

Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment

Qiong-Hua Chen, Jing-Yang Zheng, Yu-Qin Zhu, Jun-Yao Zhang, Chun-Yan Lin, Xue-E Zhuang, Jing Cheng, Xiao-Yi Huang

World J Stem Cells 17(9):109715. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109715

Abstract (128) | Core Tip (117) | Full Article (HTML) (375) | Figures (1-6) (88) | Full Article (PDF)-4940K (81) | Full Article with Cover (PDF)-5285K (71) | Full Article (XML)-77K (57) | Audio-1018K (41) | Received: 05/19/2025 | Revised: 06/17/2025 | Accepted: 08/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (52) | Timeline of Article Publication (0) | Cite | (55) | (44) | (0) | (0) | (0) | (12) | (672) | Open

Letter to the Editor

Human umbilical cord mesenchymal stromal cell-derived extracellular vesicles alleviate radiation induced pulmonary fibrosis

Jing-Jing Wang, Hong-Jie Xu

World J Stem Cells 17(9):111341. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.111341

Abstract (149) | Core Tip (111) | Full Article (HTML) (448) | Full Article (PDF)-402K (103) | Full Article with Cover (PDF)-749K (66) | Full Article (XML)-69K (63) | Audio-884K (64) | Received: 07/03/2025 | Revised: 07/21/2025 | Accepted: 09/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (46) | Timeline of Article Publication (2) | Cite | (44) | (55) | (0) | (0) | (0) | (14) | (680) | Open

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