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Editorial
An annual topic highlight: Alcohol and liver, 2011 
Natalia A Osna 
World J Gastroenterol 17(20):2455-2455. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2455
Topic Highlight
Epigenetic regulation in alcoholic liver disease 
Pranoti Mandrekar 
World J Gastroenterol 17(20):2456-2464. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2456
Histone modifications and alcohol-induced liver disease: Are altered nutrients the missing link? 
Akshata Moghe, Swati Joshi-Barve, Smita Ghare, Leila Gobejishvili, Irina Kirpich, Craig J McClain, Shirish Barve 
World J Gastroenterol 17(20):2465-2472. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2465
Targeting collagen expression in alcoholic liver disease 
Kyle J Thompson, Iain H McKillop, Laura W Schrum 
World J Gastroenterol 17(20):2473-2481. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2473
Fibronectin: Functional character and role in alcoholic liver disease 
Razia S Aziz-Seible, Carol A Casey 
World J Gastroenterol 17(20):2482-2499. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2482
Mechanisms of alcohol-mediated hepatotoxicity in human-immunodeficiency-virus-infected patients 
Gyongyi Szabo, Samir Zakhari 
World J Gastroenterol 17(20):2500-2506. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2500
Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis 
Natalia A Osna, Paul G Thomes, Terrence M Donohue Jr 
World J Gastroenterol 17(20):2507-2514. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2507
Animal models for studying hepatitis C and alcohol effects on liver 
David F Mercer 
World J Gastroenterol 17(20):2515-2519. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2515
Role of lipid rafts in liver health and disease 
Angela Dolganiuc 
World J Gastroenterol 17(20):2520-2535. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2520
microRNAs: Fad or future of liver disease 
Ashley M Lakner, Herbert L Bonkovsky, Laura W Schrum 
World J Gastroenterol 17(20):2536-2542. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2536
Hepatic stellate cells and innate immunity in alcoholic liver disease 
Yang-Gun Suh, Won-Il Jeong 
World J Gastroenterol 17(20):2543-2551. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2543
Role of MGST1 in reactive intermediate-induced injury 
Courtney S Schaffert 
World J Gastroenterol 17(20):2552-2557. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2552
Proteasome inhibitor treatment in alcoholic liver disease 
Fawzia Bardag-Gorce 
World J Gastroenterol 17(20):2558-2562. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2558
Original Article
siRNA targeting Livin decreases tumor in a xenograft model for colon cancer 
Bo-Young Oh, Ryung-Ah Lee, Kwang Ho Kim 
World J Gastroenterol 17(20):2563-2571. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2563
Brief Article
Differential protein expression during colonic adaptation in ultra-short bowel rats 
Hai-Ping Jiang, Tao Chen, Guang-Rong Yan, Dan Chen 
World J Gastroenterol 17(20):2572-2579. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2572
Case Report
Non-cirrhotic portal hypertension with large regenerative nodules: A diagnostic challenge 
Umberto Vespasiani Gentilucci, Paolo Gallo, Giuseppe Perrone, Riccardo Del Vescovo, Giovanni Galati, Sandro Spataro, Chiara Mazzarelli, Adriano Pellicelli, Antonella Afeltra, Antonio Picardi 
World J Gastroenterol 17(20):2580-2584. Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2580