Welcome to World Journal of Gastroenterology


The World Journal of Gastroenterology (WJG) is an academic journal that publishes review articles and articles describing original research (basic or clinical) in the fields of gastroenterology, hepatology, gastrointestinal surgery, and gastrointestinal endoscopy. With the aim of advancing knowledge in each of these fields, the WJG gives topical priority to related major diseases and their clinical management; frequently published disease topics are gastric cancer, colorectal cancer, hepatocellular carcinoma, pancreatic cancer, inflammatory bowel disease, irritable bowel syndrome, hepatitis C, hepatitis B, nonalcoholic fatty liver disease, and liver transplantation. All articles published in the WJG comply with the Code of Conduct of the Committee on Publication Ethics (COPE) and the requirements of Academic Rules and Norms. No restrictions are imposed on numbers of words, figures (color, B/W), tables or references for any articles published in the WJG, allowing authors to tell a whole story. TheWJG readership audience is global, representing 168 countries and regions, with an average number of 30,000 visits to the online journal per day. For details, please see http://www.wjgnet.com/1007-9327/VisitStatistics.aspx.


We encourage gastroenterologists and hepatologistsworldwide to submit manuscripts to the WJG describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.


The usual times related to all publication processes of the WJG are as follows: from manuscript receipt to peer review: 2-4 weeks; from initial manuscript acceptance, with revisions, to return of the revised manuscript from the authors: 4-5 weeks; from return of the revised manuscript from the authors to final acceptance: 1-2 weeks; from final acceptance to an article in press: 2 days; from article in press designation to formal release of the electronic version and all online documentation: 2-9 weeks. The WJG’s acceptance rate: 35%. Submit here >>

Published Issues
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Geoffrey Burnstock, DSc, FAA, FRCS(Hon), FRS, PhD, Professor; Hugh Freeman, FRCP(C), MD, MSc, Professor; Damian Garcia-Olmo, MD, PhD, Doctor, Professor, Surgeon; Stephen Strom, PhD, Professor; Andrzej Tarnawski, DSc, MD, PhD, Professor


Science Citation Index Expanded(Web of Science), Current Contents/Clinical Medicine, Journal Citation Reports, Index Medicus, MEDLINE, PubMed, and PubMed Central.

Impact Factor

2.369/2014, 2.671/5 year (Data from the 2014 edition of Journal Citation Reports®).


1007-9327 (print) and 2219-2840 (online)

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Contents Volume 22  Issue 7  February 21, 2016
Pharmacological cyclin dependent kinase inhibitors: Implications for colorectal cancer  
Archana Balakrishnan, Arpita Vyas, Kaivalya Deshpande, Dinesh Vyas
World J Gastroenterol 22(7):2159-2164. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2159
Topic Highlight
Diagnostic imaging and radiation exposure in inflammatory bowel disease  
Nekisa Zakeri, Richard CG Pollok
World J Gastroenterol 22(7):2165-2178. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2165
Diet therapy for inflammatory bowel diseases: The established and the new  
Franziska Durchschein, Wolfgang Petritsch, Heinz F Hammer
World J Gastroenterol 22(7):2179-2194. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2179
Role of regulatory T cell in the pathogenesis of inflammatory bowel disease  
Akiko Yamada, Rieko Arakaki, Masako Saito, Takaaki Tsunematsu, Yasusei Kudo, Naozumi Ishimaru
World J Gastroenterol 22(7):2195-2205. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2195
miRNAs as new molecular insights into inflammatory bowel disease: Crucial regulators in autoimmunity and inflammation  
Xiao-Min Xu, Hong-Jie Zhang
World J Gastroenterol 22(7):2206-2218. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2206
Gut microbiota role in irritable bowel syndrome: New therapeutic strategies  
Eleonora Distrutti, Lorenzo Monaldi, Patrizia Ricci, Stefano Fiorucci
World J Gastroenterol 22(7):2219-2241. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2219
Inflammation in irritable bowel syndrome: Myth or new treatment target?  
Emanuele Sinagra, Giancarlo Pompei, Giovanni Tomasello, Francesco Cappello, Gaetano Cristian Morreale, Georgios Amvrosiadis, Francesca Rossi, Attilio Ignazio Lo Monte, Aroldo Gabriele Rizzo, Dario Raimondo
World J Gastroenterol 22(7):2242-2255. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2242
Management of pancreatic fluid collections: A comprehensive review of the literature  
Amy Tyberg, Kunal Karia, Moemen Gabr, Amit Desai, Rushabh Doshi, Monica Gaidhane, Reem Z Sharaiha, Michel Kahaleh
World J Gastroenterol 22(7):2256-2270. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2256
Hepatitis E virus: An ancient hidden enemy in Latin America  
Nora A Fierro, Mauricio Realpe, Tzintli Meraz-Medina, Sonia Roman, Arturo Panduro
World J Gastroenterol 22(7):2271-2283. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2271
Genomic characterization of esophageal squamous cell carcinoma: Insights from next-generation sequencing  
Yasushi Sasaki, Miyuki Tamura, Ryota Koyama, Takafumi Nakagaki, Yasushi Adachi, Takashi Tokino
World J Gastroenterol 22(7):2284-2293. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2284
Role of Tim-3 in hepatitis B virus infection: An overview  
Yuan Liu, Li-Fen Gao, Xiao-Hong Liang, Chun-Hong Ma
World J Gastroenterol 22(7):2294-2303. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2294
Chronic pancreatitis: A diagnostic dilemma  
Sinead N Duggan, Hazel M Ní Chonchubhair, Oladapo Lawal, Donal B O’Connor, Kevin C Conlon
World J Gastroenterol 22(7):2304-2313. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2304
Basic Study
Mutation analysis of 13 driver genes of colorectal cancer-related pathways in Taiwanese patients  
Yuli Christine Chang, Jan-Gowth Chang, Ta-Chih Liu, Chien-Yu Lin, Shu-Fen Yang, Cheng-Mao Ho, William Tzu-Liang Chen, Ya-Sian Chang
World J Gastroenterol 22(7):2314-2325. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2314
Choledochojejunostomy with an innovative magnetic compressive anastomosis: How to determine optimal pressure?  
Fei Xue, Hong-Chang Guo, Jian-Peng Li, Jian-Wen Lu, Hao-Hua Wang, Feng Ma, Ya-Xiong Liu, Yi Lv
World J Gastroenterol 22(7):2326-2335. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2326
Retrospective Study
Recurrent colorectal cancer after endoscopic resection when additional surgery was recommended  
Yukiko Takatsu, Yosuke Fukunaga, Shunsuke Hamasaki, Atsushi Ogura, Jun Nagata, Toshiya Nagasaki, Takashi Akiyoshi, Tsuyoshi Konishi, Yoshiya Fujimoto, Satoshi Nagayama, Masashi Ueno
World J Gastroenterol 22(7):2336-2341. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2336
Risk factors of biliary intervention by imaging after living donor liver transplantation  
Soon Kyu Lee, Jong Young Choi, Dong Myung Yeo, Young Joon Lee, Seung Kew Yoon, Si Hyun Bae, Jeong Won Jang, Hee Yeon Kim, Dong Goo Kim, Young Kyoung You
World J Gastroenterol 22(7):2342-2348. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2342
Using typical endoscopic features to diagnose esophageal squamous papilloma  
Ming-Wun Wong, Ming-Joug Bair, Shou-Chuan Shih, Cheng-Hsin Chu, Horng-Yuan Wang, Tsang-En Wang, Chen-Wang Chang, Ming-Jen Chen
World J Gastroenterol 22(7):2349-2356. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2349
Clinical Trials Study
Effects of endoplasmic reticulum stress on the expression of inflammatory cytokines in patients with ulcerative colitis  
Nan Li, Xue-Ming Wang, Li-Jun Jiang, Meng Zhang, Na Li, Zhen-Zhen Wei, Nan Zheng, Ya-Jiao Zhao
World J Gastroenterol 22(7):2357-2365. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2357
Observational Study
Endoscopic dilation of complete oesophageal obstructions with a combined antegrade-retrograde rendezvous technique  
Reto Bertolini, Christa Meyenberger, Paul Martin Putora, Franziska Albrecht, Martina Anja Broglie, Sandro J Stoeckli, Michael Christian Sulz
World J Gastroenterol 22(7):2366-2372. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2366
CD24 genetic variants contribute to overall survival in patients with gastric cancer  
Zhi-Fang Jia, Li-Zhong Wang, Xue-Yuan Cao, Chuan Wang, Dong-Hui Cao, Xing Wu, Li-Li You, Mei-Shan Jin, Yin-Ping Wang, Bao-Sen Zhou, Jing Jiang
World J Gastroenterol 22(7):2373-2382. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2373
Case Report
Rare type of pancreatitis as the first presentation of anti-neutrophil cytoplasmic antibody-related vasculitis  
Tomoya Iida, Takeya Adachi, Tetsuya Tabeya, Suguru Nakagaki, Takashi Yabana, Akira Goto, Yoshihiro Kondo, Kiyoshi Kasai
World J Gastroenterol 22(7):2383-2390. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2383
Cystic micropapillary neoplasm of peribiliary glands with concomitant perihilar cholangiocarcinoma  
Tsuneyuki Uchida, Yusuke Yamamoto, Takaaki Ito, Yukiyasu Okamura, Teiichi Sugiura, Katsuhiko Uesaka, Yasuni Nakanuma
World J Gastroenterol 22(7):2391-2397. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2391
Laparoscopic resection of adult colon duplication causing intussusception  
Kennoki Kyo, Masaki Azuma, Kazuya Okamoto, Motohiro Nishiyama, Takahiro Shimamura, Atsushi Maema, Motoaki Shirakawa, Toshio Nakamura, Kenji Koda, Hidetaro Yokoyama
World J Gastroenterol 22(7):2398-2402. Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2398