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Contents Volume 18 Issue 7 July 26, 2026
Editorial
Mesenchymal stem cell secretome and exosomes as potential advanced therapy medicinal products for treating a failing heart
Syed Mohammad Habib, Mohammad Fateh Martini, Yacoub Nail Hamdan Abu-Hamdan, Omran Mohammed Marwan Shrebaty, Khawaja Husnain Haider 
World J Stem Cells 18(7):113871. Published online Jul 26, 2026. doi: 10.4252/wjsc.113871
Human umbilical cord mesenchymal stem cells in irritable bowel syndrome: Mechanistic and translational insights
Eric Michael Kunz, Joseph Patrick Carroll, Russell James Schoeller III, Brandon Lucke-Wold 
World J Stem Cells 18(7):117946. Published online Jul 26, 2026. doi: 10.4252/wjsc.117946
Opinion Review
Enhancing mesenchymal stem cell function with epiregulin in tissue engineering: From tissue regeneration to gut microbiota modulation
Andrei A Dudun, Garina A Bonartseva, Anton P Bonartsev 
World J Stem Cells 18(7):119865. Published online Jul 26, 2026. doi: 10.4252/wjsc.119865
Bone marrow niche adaptation, leukemic stem cell persistence, and therapeutic resistance in FLT3-mutated leukemia
Huai-Bin Zhang, Hui-Hui Jiang, Jian-Chuan Deng, Nan Zhang 
World J Stem Cells 18(7):119893. Published online Jul 26, 2026. doi: 10.4252/wjsc.119893
Review
Mesenchymal stem cell-derived extracellular vesicles as next generation drug delivery platforms
Sara Akhtar Khan, Saurabh Kumar Jha, Prachi Tiwari, Jagriti Narang, Vinamre Gupta, Sachin Kumar Singh, Kushi Anand, Ramya Lakshmi Rajendran, Prakash Gangadaran, Suhel Parvez 
World J Stem Cells 18(7):120363. Published online Jul 26, 2026. doi: 10.4252/wjsc.120363
Stem cell-based strategies for hearing restoration: Current advances and future perspectives
Yan-Ji Qu, Jia-Yu Wang, Zhe Wang, Wei Yao, Zhong-Fang Xia 
World J Stem Cells 18(7):122823. Published online Jul 26, 2026. doi: 10.4252/wjsc.122823
Minireviews
Effects of microenvironmental engineering on the stemness of human umbilical cord mesenchymal stem cells
Cun-Min Zhou, Cheng-Yuan Bao, Fei-Fei Ma, Meng Li, Xiao-Qin Ha 
World J Stem Cells 18(7):120910. Published online Jul 26, 2026. doi: 10.4252/wjsc.120910
Retrospective Study
Clinical significance of mesenchymal stem cells exosomal microRNAs in predicting prognosis and inflammatory response of esophageal cancer
Jin-Lin Wang, Ya-Xuan Niu, Han-Xiao Li, Fa-Cai Cui, Xiao Chen 
World J Stem Cells 18(7):119714. Published online Jul 26, 2026. doi: 10.4252/wjsc.119714
Circulating stem/progenitor cell biomarkers and prognosis in critically ill patients with gastrointestinal bleeding
Bin Xie, Jin Zhang, Yan-Hua Wen, Hui-Feng Zhao 
World J Stem Cells 18(7):119749. Published online Jul 26, 2026. doi: 10.4252/wjsc.119749
Basic Study
miR-140-3p in exosomes derived from bone-marrow mesenchymal stem cells inhibits pyrotoisosis by targeting PTEN under high-glucose condition
Yue Wu, Wen-Hui Yin, Hong-Jing Wang, Hui Cai 
World J Stem Cells 18(7):118557. Published online Jul 26, 2026. doi: 10.4252/wjsc.118557
Exosomal miR-181d-5p promotes spinal cord injury repair by driving microglial polarization from M1 to M2 phenotype
Wei Wang, Bin Wang, Hua Yin 
World J Stem Cells 18(7):119260. Published online Jul 26, 2026. doi: 10.4252/wjsc.119260
Regulatory T cell-derived exosomes regulate β-catenin expression to promote the stem cell-like properties of hepatocellular carcinoma
Yi-Jun Tu, Yun-Qi Liu, Hong-Yang Cai, Yan-Yan Pan, Chang Liu 
World J Stem Cells 18(7):119892. Published online Jul 26, 2026. doi: 10.4252/wjsc.119892
Platelet-derived mitochondria transfer accelerates fracture healing by promoting osteogenic differentiation and metabolic reprogramming of adipose-derived stem cells
Zhu Pan, Rui Zhang, Gai-Mei Du, Ji-Hai Yi, Jin Bao, Cai-Dong Liu 
World J Stem Cells 18(7):119895. Published online Jul 26, 2026. doi: 10.4252/wjsc.119895
Integrated patient induced pluripotent stem cell models and Gaa-/- mice reveal central nervous system neural pathology in infantile-onset Pompe disease
Yi-Chang Jiao, Dan-Dan Zhao, Hai-Yan Zhang, Fu-Chen Liu 
World J Stem Cells 18(7):120578. Published online Jul 26, 2026. doi: 10.4252/wjsc.120578
Systematic Reviews
Efficacy and safety of cell-based regenerative therapies for fistula-related diseases: An umbrella review of systematic reviews
Yun-Long Duan, Yong-Hao Wen, Si-Ai Chen, Ru Nie, Ming-Quan Pang, Man-Jun Deng, Zhi-Xin Wang, Hai-Ning Fan 
World J Stem Cells 18(7):122048. Published online Jul 26, 2026. doi: 10.4252/wjsc.122048
Correspondence
Letter to the Editor: Sclerostin knockdown in human umbilical cord mesenchymal stem cells confers superior therapeutic efficacy against steroid-induced osteonecrosis
Wei Zhang, Wen-Hui Chu 
World J Stem Cells 18(7):115076. Published online Jul 26, 2026. doi: 10.4252/wjsc.115076
Letter to the Editor: Cell source dictates the effect - a critical consideration for exosome-based cancer therapies
Feng-Juan Lyu 
World J Stem Cells 18(7):116082. Published online Jul 26, 2026. doi: 10.4252/wjsc.116082
Letter to the Editor: Extracellular vesicles in diabetic bladder dysfunction - a promising cell-free therapeutic avenue from amniotic fluid stem cells
Zhuo-Yin Liang, Hai-Sheng Hu 
World J Stem Cells 18(7):117525. Published online Jul 26, 2026. doi: 10.4252/wjsc.117525
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