World Journal of Gastroenterology - Baishideng Publishing Group

Advanced Search

BPG is committed to discovery and dissemination of knowledge

JOURNAL HOME

Number of total visits: 77940263

Number of visits today: 212089

Number of downloads: 37736972

PUBLISHING PARTNER

INDEXING/ABSTRACTING

MEMBERSHIP

BPG JOURNAL LIST

Open-Access Journal

Other Issues: Previous | Next | Latest | Archive | Download full issue 44 (106)

Contents Volume 31 Issue 44 November 28, 2025

Editorial

Redefining therapeutic thresholds and global guidelines: Toward precision management of intermediate-sized rectal neuroendocrine tumors

Dan Hu, Jiang Yu, Meng-Xue Wang, Hao-Ling Zhang

World J Gastroenterol 31(44):114263. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.114263

Abstract (149) | Core Tip (137) | Full Article (HTML) (618) | Tables (1-1) (127) | Full Article (PDF)-398K (135) | Full Article with Cover (PDF)-726K (172) | Full Article (XML)-75K (58) | Audio-222K (14) | Received: 09/14/2025 | Revised: 10/10/2025 | Accepted: 10/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (3) | Timeline of Article Publication (4) | Cite | (61) | (51) | (0) | (0) | (0) | (21) | (1110) | (2) | Open

Review

Neuroimmune interactions in inflammatory bowel disease: Role of intestinal macrophages and the cholinergic pathway

Lie Zheng, Sheng-Lei Duan

World J Gastroenterol 31(44):109440. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.109440

Abstract (124) | Core Tip (124) | Full Article (HTML) (1081) | Figures (1-3) (90) | Full Article (PDF)-1729K (150) | Full Article with Cover (PDF)-2056K (228) | Full Article (XML)-231K (53) | Audio-209K (18) | Received: 05/10/2025 | Revised: 08/07/2025 | Accepted: 10/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (692) | Timeline of Article Publication (2) | Cite | (62) | (54) | (0) | (0) | (0) | (2) | (1602) | (4) | Open

Role of artificial intelligence in the detection and characterization of gastrointestinal premalignant and early malignant lesions

Noelle El Asmar, Mariam Baydoun, Jamil Mrad, Kassem Barada

World J Gastroenterol 31(44):111160. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.111160

Abstract (159) | Core Tip (174) | Full Article (HTML) (1207) | Figures (1-3) (85) | Tables (1-9) (85) | Full Article (PDF)-927K (255) | Full Article with Cover (PDF)-1252K (288) | Full Article (XML)-654K (50) | Audio-804K (20) | Received: 06/24/2025 | Revised: 07/20/2025 | Accepted: 10/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (379) | Timeline of Article Publication (1) | Cite | (57) | (68) | (0) | (0) | (0) | (1970) | (2) | Open

Application of traditional Chinese medicine integrated therapy based on Tuina and herbal medicine in pediatric diarrhea

Yu Zhu, Hai-Cheng Dong, Yao Zhang, Xiao-Ai Wang, Jun-Yi Chen, Jing-Jing Wang

World J Gastroenterol 31(44):113017. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.113017

Abstract (145) | Core Tip (155) | Full Article (HTML) (1251) | Figures (1-2) (87) | Tables (1-2) (116) | Full Article (PDF)-792K (220) | Full Article with Cover (PDF)-1119K (147) | Full Article (XML)-237K (59) | Audio-247K (54) | Received: 08/19/2025 | Revised: 09/18/2025 | Accepted: 10/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (222) | Timeline of Article Publication (4) | Cite | (61) | (112) | (0) | (0) | (0) | (24) | (1880) | (3) | Open

Advances in the study of the relationship between neurotransmitters and gastric cancer

You-Zhao Liu, Wen-Xuan Liu, Wen-Hong Deng

World J Gastroenterol 31(44):113793. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.113793

Abstract (154) | Core Tip (142) | Full Article (HTML) (893) | Figures (1-3) (118) | Tables (1-1) (106) | Full Article (PDF)-2218K (213) | Full Article with Cover (PDF)-2546K (96) | Full Article (XML)-323K (72) | Audio-561K (23) | Supplementary Material-666K (51) | Received: 09/03/2025 | Revised: 09/20/2025 | Accepted: 10/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1361) | Timeline of Article Publication (5) | Cite | (62) | (74) | (0) | (0) | (0) | (31) | (1498) | (3) | Open

Case Control Study

Diagnostic performance of serum origin recognition complex subunit 1 protein for hepatitis B virus-related hepatocellular carcinoma

Yan-Fei Feng, Tu-Mei Su, Bo-Bin Hu, Hang Wang, Qing-Mei Li, Qian-Bing Yin, Long Huang, Hong-Qian Liang, Ao-Li Ren, Ming-Hua Su, Jian-Ning Jiang

World J Gastroenterol 31(44):112481. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.112481

Abstract (126) | Core Tip (132) | Full Article (HTML) (473) | Figures (1-6) (99) | Tables (1-5) (87) | Full Article (PDF)-1405K (81) | Full Article with Cover (PDF)-1734K (97) | Full Article (XML)-120K (51) | Audio-325K (18) | Received: 07/28/2025 | Revised: 09/13/2025 | Accepted: 10/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (2314) | Timeline of Article Publication (5) | Cite | (70) | (62) | (0) | (0) | (0) | (22) | (1) | (888) | (2) | Open

Retrospective Cohort Study

Retreatment hepatitis B surface antigen clearance prediction model identifies pegylated interferon alpha candidates in chronic hepatitis B

Yan-Chao Fu, Jun Li, Jia-Yin Wang, Yi-Wen Zhang, Fei Yan, Jing Chen, Qin Du, Chao Yang, Jing Liang, Qing Ye, Hui-Ling Xiang

World J Gastroenterol 31(44):112719. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.112719

Abstract (155) | Core Tip (136) | Full Article (HTML) (696) | Figures (1-5) (122) | Tables (1-2) (90) | Full Article (PDF)-1197K (114) | Full Article with Cover (PDF)-1526K (88) | Full Article (XML)-106K (53) | Audio-1375K (33) | Supplementary Material-116K (56) | Received: 08/04/2025 | Revised: 09/14/2025 | Accepted: 10/24/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (223) | Timeline of Article Publication (0) | Cite | (54) | (64) | (0) | (0) | (0) | (19) | (1163) | (2) | Open

Retrospective Study

DNA polymerase epsilon-mutant colorectal cancers: Insights into non-exonuclease domain mutation variants, microsatellite instability status, and co-mutation profiles

Ismail Taskiran, Seda Orenay-Boyacioglu, Olcay Boyacioglu, Ibrahim Halil Erdogdu, Nil Culhaci, Ibrahim Meteoglu

World J Gastroenterol 31(44):112524. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.112524

Abstract (133) | Core Tip (124) | Full Article (HTML) (746) | Figures (1-2) (80) | Tables (1-5) (104) | Full Article (PDF)-680K (113) | Full Article with Cover (PDF)-1008K (104) | Full Article (XML)-142K (57) | Audio-258K (16) | Received: 07/29/2025 | Revised: 09/13/2025 | Accepted: 10/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1236) | Timeline of Article Publication (2) | Cite | (58) | (113) | (0) | (0) | (0) | (20) | (1) | (1204) | (4) | Open

Risk factors with nomogram construction for moderate to severe pain after endoscopic full-thickness resection

Guo-Yao Sun, Teng-Jiao Gao, Yong Sun, Wen Jia, Zhuo Yang

World J Gastroenterol 31(44):112576. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.112576

Abstract (140) | Core Tip (146) | Full Article (HTML) (474) | Figures (1-2) (79) | Tables (1-2) (78) | Full Article (PDF)-701K (90) | Full Article with Cover (PDF)-1030K (112) | Full Article (XML)-71K (56) | Audio-1620K (10) | Received: 07/30/2025 | Revised: 09/06/2025 | Accepted: 10/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (370) | Timeline of Article Publication (0) | Cite | (54) | (53) | (0) | (0) | (0) | (889) | (1) | Open

Clinical Trials Study

Influence of an internet-based proactive follow-up management model on the prognosis of nonalcoholic fatty liver disease

Sui-Yi Liu, Guo-Feng Gao, Xiao-Yu Wang, Jiao Yu

World J Gastroenterol 31(44):111731. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.111731

Abstract (125) | Core Tip (163) | Full Article (HTML) (499) | Tables (1-10) (84) | Full Article (PDF)-461K (98) | Full Article with Cover (PDF)-788K (73) | Full Article (XML)-94K (53) | Audio-1398K (11) | Received: 07/29/2025 | Revised: 09/14/2025 | Accepted: 10/28/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (309) | Timeline of Article Publication (0) | Cite | (60) | (67) | (0) | (0) | (0) | (807) | (2) | Open

Randomized Controlled Trial

Covering the biopsy hole check valve with “enzymolysis gauze” reduces bacterial contamination in the endoscopy room

Hu-Bin Xia, Ying-Dong Hou, Yuan Zhang, Ai-Yu Yu, Qi Ding, Wen-Li Ruan, Yi-Shen Mao, Shu-Jiong Feng, Cong Ding, Yi-Feng Zhou

World J Gastroenterol 31(44):113650. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.113650

Abstract (142) | Core Tip (120) | Full Article (HTML) (459) | Figures (1-4) (88) | Tables (1-1) (77) | Full Article (PDF)-3332K (80) | Full Article with Cover (PDF)-3660K (65) | Full Article (XML)-91K (50) | Audio-1073K (15) | Received: 08/30/2025 | Revised: 10/10/2025 | Accepted: 10/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (147) | Timeline of Article Publication (0) | Cite | (59) | (57) | (0) | (0) | (0) | (819) | (1) | Open

Basic Study

Dexmedetomidine enhances anastomotic healing partly via the Wnt/β-catenin pathway in a rat model of colon surgery

Ying Chen, Chun-Tian Li, Jie-Bo Wang, Wen-Lu Tang, Yu Zhao, Ye Chen, Lian-Ming Liao, Liang-Cheng Zhang, Tian-Hua Lin, Zhi-Fang Cao

World J Gastroenterol 31(44):112833. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.112833

Abstract (126) | Core Tip (116) | Full Article (HTML) (552) | Figures (1-8) (88) | Tables (1-1) (87) | Full Article (PDF)-39135K (106) | Full Article with Cover (PDF)-39463K (69) | Full Article (XML)-121K (72) | Audio-293K (18) | Received: 08/06/2025 | Revised: 09/28/2025 | Accepted: 10/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (42) | Timeline of Article Publication (1) | Cite | (76) | (69) | (0) | (0) | (0) | (21) | (974) | Open

Case Report

Very-early-stage gastric amphicrine carcinoma with mixed histology: A case report and review of literature

Cai-Zhi Gao, Yuan Meng, Jin-Zhu Du, Xu Zhu

World J Gastroenterol 31(44):112187. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.112187

Abstract (135) | Core Tip (115) | Full Article (HTML) (706) | Figures (1-6) (111) | Tables (1-1) (98) | Full Article (PDF)-30241K (121) | Full Article with Cover (PDF)-30570K (108) | Full Article (XML)-86K (52) | Audio-1338K (20) | Received: 07/29/2025 | Revised: 09/10/2025 | Accepted: 10/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (4701) | Timeline of Article Publication (5) | Cite | (57) | (63) | (0) | (0) | (0) | (29) | (1196) | (1) | Open

Letter to the Editor

Prudence is never excessive: Caution warranted in 5-aminosalicylic acid derivatives withdrawal for ulcerative colitis

Antonietta Gerarda Gravina, Raffaele Pellegrino, Alessandro Federico

World J Gastroenterol 31(44):113253. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.113253

Abstract (132) | Core Tip (120) | Full Article (HTML) (617) | Full Article (PDF)-392K (88) | Full Article with Cover (PDF)-722K (173) | Full Article (XML)-48K (57) | Audio-244K (17) | Received: 08/19/2025 | Revised: 10/02/2025 | Accepted: 10/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (428) | Timeline of Article Publication (0) | Cite | (54) | (51) | (0) | (0) | (0) | (935) | Open

Risk elements and diagnostic indicators for asymptomatic immune checkpoint inhibitor-associated myocarditis in esophageal cancer

Tushar Bhadra, Brandon Lucke-Wold

World J Gastroenterol 31(44):113689. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.113689

Abstract (144) | Core Tip (123) | Full Article (HTML) (458) | Full Article (PDF)-379K (85) | Full Article with Cover (PDF)-708K (53) | Full Article (XML)-39K (47) | Audio-6486K (32) | Received: 08/31/2025 | Revised: 09/25/2025 | Accepted: 10/16/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (184) | Timeline of Article Publication (0) | Cite | (68) | (66) | (0) | (0) | (0) | (24) | (643) | Open

Peroxiredoxin 1 inhibits tumorigenesis by activating the NLR family pyrin domain containing 3/gasdermin D pathway: Advanced therapies targeting heterogeneous cell death mechanisms

Anna Smirnova, Daria Eygel, Irina Kondrasheva, Denis S Baranovskii, Ilya D Klabukov

World J Gastroenterol 31(44):114404. Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.114404

Abstract (153) | Core Tip (150) | Full Article (HTML) (447) | Full Article (PDF)-361K (72) | Full Article with Cover (PDF)-691K (77) | Full Article (XML)-39K (62) | Audio-62K (13) | Received: 09/17/2025 | Revised: 09/30/2025 | Accepted: 10/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (7) | Timeline of Article Publication (0) | Cite | (52) | (56) | (0) | (0) | (0) | (658) | Open

Write to the Help Desk

Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.