Naoki Hashimoto graduate Kobe University on 1975. With a medical degree in Japan, upon PhD in 1984 at Hyogo Medical College. Over the last 10 years, he has focused his scientific interests on the topics related to “Reflux of duodenal contents induces esophageal carcinogenesis” from the point of experimental and clinical studies. With his expertise in biomedical imaging, surgical treatment and chemoradiotherapy for advanced esophageal cancer. He was received many academic honors including European Conference on General Thoracic Surgery(2012) and OESO(2013).Innovative, translational and longstanding research has been a pursuit in his academic career.